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Cipzen-D Tablet is a combination of two medicines. It is used to reduce pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis. It is also used to relieve muscle pain, back pain, toothache, or pain in the ear and throat.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 07 Apr 2026 | 03:01 PM (IST)
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General Information

Contains

Diclofenac (50mg)+ Serratiopeptidase (10mg)

Marketer

Cipla Ltd

Storage

Store below 25°C
The content is shown in English
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Cipzen-D Tablet image
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Cipzen-D Tablet image
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Cipzen-D Tablet image

Product introduction

Cipzen-D Tablet can be taken with or without food. The dose will depend on what you are taking it for and how well it helps your symptoms. You should take it as advised by your doctor. Do not take more or use it for a longer duration than recommended by the doctor.

The most common side effects of this medicine include nausea, vomiting, heartburn, stomach pain, indigestion, diarrhea, and loss of appetite. If any of these side effects bother you or get worse, you should speak to your doctor. Your doctor may be able to suggest ways of preventing or reducing the side effects.

Before taking it, you should let your doctor know if you have a history of ulcer or bleeding in your stomach, high blood pressure, or have any trouble with your heart, kidneys, or liver. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Pregnant or breastfeeding women should consult their doctor before starting treatment. You should also avoid drinking alcohol while you are taking this medicine, as alcohol can cause excessive drowsiness.

Uses of Cipzen-D Tablet

Benefits of Cipzen-D Tablet

Pain relief
Cipzen-D Tablet is a combination of medicines that is used for short term relief of pain, inflammation and swelling. It inhibits release of those chemical messengers in the brain that tell us that we have pain. It effectively relieves back pain, earache, throat pain, toothache, periods pain and pain due to arthritis too.
Take Cipzen-D Tablet as prescribed by the doctor to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Cipzen-D Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cipzen-D
  • Nausea
  • Vomiting
  • Heartburn
  • Stomach pain
  • Indigestion
  • Diarrhea
  • Loss of appetite

How to use Cipzen-D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cipzen-D Tablet may be taken with or without food.

How Cipzen-D Tablet works

Cipzen-D Tablet is a combination of two medicines: Diclofenac and Serratiopeptidase. Diclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers in the brain that cause pain and inflammation (redness and swelling). Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation and promotes healing.

All substitutes for Cipzen-D Tablet

For information purposes only. Consult a doctor before taking any medicine.

Lyser D Tablet

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₹16.87/tablet
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Emanzen-D Tablet

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₹21.8/tablet
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SN 15 Plus Tablet

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₹10/tablet
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Tolpa D Tablet

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₹14.3/tablet
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Seradic Tablet

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₹13.5/tablet
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Quick tips

  • This combination medicine helps relieve pain and inflammation.
  • Take it with food to avoid getting an upset stomach.
  • Take it as per the dose and duration prescribed by your doctor.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how Cipzen-D Tablet affects you.
  • Avoid consuming alcohol when taking this medicine as it may cause excessive drowsiness and increase the risk of liver damage.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cipzen-D Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Cipzen-D Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Cipzen-D Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Cipzen-D Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Cipzen-D Tablet may cause headaches, blurred vision, dizziness or drowsiness in some patients. This may affect your ability to drive.
Kidney

Kidney

CAUTION
Cipzen-D Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Cipzen-D Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Regular monitoring of liver function tests is recommended in patients with liver disease if this medicine is to be taken for a long time.

Frequently asked questions

Cipzen-D Tablet is a combination of two medicines: Diclofenac and Serratiopeptidase. This medication helps in relieving pain and inflammation. It works by lowering the levels of chemical substances in the body that cause pain and inflammation.
Yes, Cipzen-D Tablet is safe for most of the patients. However, in some patients it may cause common unwanted side effects like nausea, vomiting, stomach pain, heartburn and diarrhea. Inform your doctor as soon as possible if you experience any persistent problem due to the medication.
Cipzen-D Tablet is usually used for short term and can be discontinued when the pain is relieved. However, Cipzen-D Tablet should be continued if your physician has advised you to do so.
Yes, the use of Cipzen-D Tablet can cause nausea and vomiting. Taking it with milk, food or with antacids can prevent nausea. Avoid taking fatty or fried foods along with this medicine. In case of vomiting, drink plenty of water or other fluids by taking small frequent sips. Talk to your doctor if vomiting persists and you notice signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Do not take any other medicines without speaking to a doctor.
Yes, the use of Cipzen-D Tablet can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for some time and resume once you feel better.
The use of Cipzen-D Tablet is considered to be harmful in patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with a history of heart failure, high blood pressure, and liver or kidney disease.
Cipzen-D Tablet can be taken with Vitamin B-complex preparations. While Cipzen-D Tablet helps to relieve pain, Vitamin B-complex can help to correct the vitamin deficiency that might be causing the symptoms.
No, Cipzen-D Tablet preferably should not be taken for stomach pain without consulting a physician. This drug can increase stomach acid secretion which may aggravate an unknown underlying condition.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Diclofenac. Rouse Boulevard, Philadelphia: Iroko Pharmaceuticals; 1998 [revised Oct. 2013]. [Accessed 02 Apr. 2019] (online) Available from:
  2. Bhagat S, Agarwal M, Roy V. Serratiopeptidase: A systematic review of the existing evidence. Int J Surg. 2013;11(3):209-17. [Accessed 02 Apr. 2019] (online) Available from:
  3. Diclofenac. Daventry, Northamptonshire: Dexcel Pharma Ltd.; 1996 [revised 20 Dec. 2017]. [Accessed 02 Apr. 2019] (online) Available from:
  4. PubChem. Serratiopeptidase. [Accessed 02 Apr. 2019] (online) Available from:
  5. Diclofenac Potassium and Serratiopeptidase. Panchkula, Haryana: GNova Biotech Pvt. Lytd.; [Accessed 12 Jan. 2026] (online). Available from:
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User feedback

Twice A Day
69%
Once A Day
19%
Thrice A Day
10%
Alternate Day
1%
Four Times A Day
1%
Pain relief
81%
Others
10%
Dental pain
6%
Swelling
2%
Rheumatoid arthritis
1%
Average
46%
Excellent
33%
Poor
21%
Stomach pain
26%
Heartburn
21%
Nausea
16%
No Side Effect
11%
Indigestion
11%
With food
79%
With or without food
18%
Empty stomach
3%
Expensive
48%
Average
43%
Not Expensive
9%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Cipzen-D Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's â„ž and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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