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Cernos Gel is a medicine used in the treatment of male hypogonadism caused due to low testosterone levels. It is only prescribed to men with known medical conditions. It helps in restoring the level of testosterone in the male body.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)
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Cernos Gel image
Cernos Gel image
Cernos Gel image
Cernos Gel image
Cernos Gel image
Cernos Gel image

Product introduction

Cernos Gel is injected directly into the skin or muscles under the medical supervision of a doctor. The dose and how often you take the injection depends on what you are using it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.


The most common side effects of this medicine include acne, breast enlargement in male, voice change, and injection site reactions (pain, swelling, redness). If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.  Some side effects may mean you should stop taking this medicine shortness of breath, frequent or persistent erections, and low sperm count.


Before taking this medicine, tell your doctor if you have ever had high blood pressure, heart attack, and stroke. Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Your doctor might perform regular blood tests to keep track of testosterone, and prostate-specific antigen (PSA) levels.

Uses of Cernos Gel

  • Treatment of Male hypogonadism

Benefits of Cernos Gel

Treatment of Male hypogonadism
Male hypogonadism is a condition in which the body does not produce enough testosterone (male sex hormone). Cernos Gel injections help improve the level of testosterone in your body. This helps in maintaining better sex life, improve overall physical appearance, gives good mood and boost overall confidence. Cernos Gel also helps in muscle building and development of bones. This treatment has few side effects so it is advisable to always take the injection under a doctor’s supervision only. You should continue taking it as long as it is prescribed even if you feel better.

Side effects of Cernos Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cernos
  • Application site reactions (burning, irritation, itching and redness)
  • Altered laboratory test values
  • Change in blood pressure
  • Increased red blood cells
  • Headache

How to use Cernos Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Cernos Gel works

Cernos Gel is similar to the natural male hormone, testosterone. It works by replenishing the deficient testosterone levels in adult men. Lack of testosterone may cause various health problems including impotence, infertility, low sex drive, tiredness, depressive mood and bone loss.

All substitutes for Cernos Gel

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Cernos Gel for the treatment of low testosterone levels.
  • It should be applied once a day, preferably in the morning.
  • Apply it as a thin layer onto clean, dry, healthy, unbroken skin over the shoulders or upper arms.
  • Cover the application area after it's dry, otherwise it can rub off on people.
  • Do not apply the gel to the genitals as this may cause irritation.
  • Your doctor may get your blood tests done regularly to monitor red blood cells, liver function, testosterone, and prostate specific antigen (PSA) levels while taking Cernos Gel.
  • Inform your doctor if you experience symptoms such as frequent or persistent erections, irritability, nervousness or weight gain after starting treatment with this medicine.
  • Your doctor will administer this injection into a muscle or skin.
  • Your doctor may monitor you for 30 minutes after your shot to make sure you do not develop breathing problems or get a severe allergic reaction due to the medicine.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

UNSAFE
Cernos Gel is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Cernos Gel is not indicated for use in women.
Breast feeding

Breast feeding

UNSAFE
Cernos Gel is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Cernos Gel is not indicated for use in women.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking Cernos with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Warfarin (Oral Route)

Your doctor may monitor the clotting characteristics of your blood and/or adjust the dose of Warfarin accordingly. Testosterone may increase the effect of Warfarin.

Frequently asked questions

Cernos Gel contains a synthetic form of testosterone (a male sex hormone). It is used in the treatment of male hypogonadism (a condition in which the body does not produce enough testosterone).
Apply this medicine, onto clean, dry intact skin (preferably over abdomen or shoulders) once a day at the same time each day. Rub the gel in gently with one finger until dry, and then cover the area with loose clothing (e.g. T-shirt, shorts, pants). After finishing, wash your hands with soap and water. The dose of this medicine is decided by your doctor and make sure to follow it.
This medicine, may be transferred from you to the other person from close skin to skin contact. It might result in increase the testosterone levels in the other person. The prolonged or repeated exposure may cause few side effects (excess hair growth, deep voice, menstrual irregularities in women). To prevent this, cover the application site with the loose clothing once the gel has dried and always wash your hands with soap and water after applying it.
The most common side effect of using Cernos Gel is skin reactions at the site of application such as burning or prickling sensation, dryness, rash, redness or itchiness. Other common side effects include acne, abnormal lab test values, and prostatic disorders (such as enlarged prostate, BPH, and elevated PSA). If any of these side effect bother you, please consult with your doctor.
No, Cernos Gel should not be used for increasing muscle mass and physical ability in healthy individuals, as this may cause harmful effects when used inappropriately. Also, in healthy individuals, if Cernos Gel is given externally, it may cause hormonal imbalance.
Cernos Gel should not be given to men with breast cancer, prostate cancer and kidney disease. It should be avoided in patients who had or presently have liver cancer and in those who have increased levels of calcium in blood. It should not be used by females, children below 18 years, and elderly patients more than 65 years of age.
Cernos Gel may decrease blood glucose levels, and therefore, the dose of antidiabetic medicines should be reduced. Consult your doctor for advice.
You should get blood tests done more frequently for checking your bleeding time (time taken to stop bleeding) when you are taking warfarin along with Cernos Gel, especially when starting and stopping Cernos Gel. Talk to your doctor for advice.
While some of the effects of Cernos Gel may start showing effects after 3 weeks, some may take longer. For example, effect on sexual interest appears after 3 weeks, while changes in erections/ejaculations may take up to 6 months.
The major health risks associated with the use of Cernos Gel in men are heart attack, stroke, and prostatic carcinoma.

Fact Box

Chemical Class

Androgen derivative

Habit Forming

No

Therapeutic Class

SEX STIMULANTS REJUVENATORS

Action Class

Androgens

References

  1. Snyder PJ. Androgens. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1195-206.
  2. Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 719-22.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1335-37.
  4. Testosterone buccal system. Milan, Italy: Mipharm S.p.A; 1953 [revised Oct. 2016]. [Accessed 17 Jun. 2019] (online) Available from:
  5. Testosterone. Malvern, Pennsylvania: Auxilium Pharmaceuticals, Inc.; 2009. [Accessed 03 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
  7. Testosterone gel [Prescribing Information]. North Chicago, IL: AbbVie Inc.; 2013. [Accessed 20 Feb. 2024] (online) Available from:
  8. Testosterone gel. Prescribing Information. Malvern, USA: Endo USA; 2025. [Accessed 11 Sep. 2025] (online) Available from:
  9. Testosterone. Prescribing Information. Malvern, PA: Endo USA; 2025. [Accessed 10 Nov. 2025] (online) Available from:
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User feedback

Once A Day
86%
Twice A Day
7%
Twice A Week
3%
Alternate Day
2%
Thrice A Day
1%
Male hypogonadism
80%
Others
20%
Poor
39%
Average
34%
Excellent
28%
No Side Effect
59%
Increased red blood cells
11%
Dizziness
5%
Leg pain
5%
High blood pressure
3%
With or without food
59%
With food
28%
Empty stomach
14%
Expensive
46%
Average
40%
Not Expensive
15%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Cernos Gel. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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