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CEFUP 500MG/250MG INJECTION

Injection
MRP: Rs. 20.40 for 1 vial(s) (1 injection each)
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Composition for CEFUP

Cefotaxime(500 mg),Sulbactam(250 mg)

food interaction for CEFUP

alcohol interaction for CEFUP

pregnancy interaction for CEFUP

lactation interaction for CEFUP

food
alcohol
pregnancy
lactation
There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Cefup 500mg/250mg injection is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
PROBABLY SAFE
Unknown. Human and animal studies are not available. Please consult your doctor.

SALT INFORMATION for CEFUP

Cefotaxime(500 mg)

Uses

Cefotaxime is used in the treatment of bacterial infections and typhoid fever.

How it works

Cefotaxime is an antibiotic. It kills the bacteria by attacking their cell wall. Specifically, it prevents the synthesis of a substance in the cell wall called peptidoglycan, which provides the cell wall with the strength required for survival of bacteria in human body.

Common side effects

Vomiting, Nausea, Infection, Acne, Acne-like rash, Facial swelling, Allergic reaction, Blisters on skin, Chills, Difficulty in swalloing, Shortness of breath, Skin rash, Fever, Hoarseness of voice, Injection site bleeding, Black and bloody stools, Skin swelling, Skin redness, Sore throat, Stomach pain, Stomach cramp, Tongue swelling, Throat swelling, Itching, Urticaria
Sulbactam(250 mg)

Uses

Sulbactam is used in the treatment of bacterial infections.

How it works

Sulbactam belongs to group of medicines called betalactamase Inhibitor with very weak action against bacteria.  Beta-lactamase inhibitors are available only in fixed combinations with specific penicillins (beta-lactam antibiotics) such as amoxicillin, ampicillin, piperacillin, and ticarcillin. It works by preventing destruction of beta-lactam antibiotics from chemicals released from bacteria and extends their spectrum of activity.

Common side effects

Vomiting, Nausea, Diarrhoea, Abdominal pain, Jaundice, Abnormal liver function tests, Allergic reaction, Hives, Redness of skin, Ankle swelling, Limb swelling, Difficulty in swalloing, Shortness of breath, Facial swelling, Skin swelling, Tongue swelling, Throat swelling, Injection site bruising, Injection site bleeding, Stomach cramp, Wheezing

SUBSTITUTES for CEFUP

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Top Physicians

  • Dr. Prabhat Kumar Jha
    MBBS, MD
    4.7
  • Dr. Ashutosh Shukla
    MBBS, MD, Diploma, Fellowship
    4.6
  • Dr. R. S. Rawat
    MBBS, MD
    4.5
  • Dr. R. R. Dutta
    MBBS, MD
    4.4
  • Dr. Kartavya Shah
    MBBS, DNB
    4.2

Expert advice for CEFUP

  • Cefotaxime is usually given by a doctor or a nurse as an injection directly into the vein or muscle.
  • Do not drive or operate machinery as you may feel sleepy or dizzy while being treated with cefotaxime.
  • Tell your doctor if you are taking cefotaxime and undergoing urine glucose test or Coombs test, as it may affect the result.
  • Do not start or continue cefotaxime if you have a kidney problem or diabetes.
  • Avoid taking cefotaximeI if you are on a controlled sodium diet because drug contain sodium.
  • Do not start or continue cefotaxime if you experience a widespread rash with blisters and peeling skin (these may be signs of Stevens-Johnson syndrome) or severe skin reaction to drugs (toxic epidermal necrolysis) or severe diarrhea (pseudomembranous colitis).
  • Do not take cefotaxime if you are pregnant or planning to become pregnant or breastfeeding.

Frequently asked questions for CEFUP

Cefotaxime

Q.Is cefotaxime a sulfa, penicillin or broad spectrum antibiotic?
Cefotaxime does not contain sulfa and is not a penicillin drug. It is a third generation, broad spectrum cephalosporin antibiotic

Q.Is cefotaxime compatible with potassium and TPN?
Yes, cefotaxime can be given with potassium and TPN (total parenteral nutrition)

Q.Is cefotaxime ototoxic (toxic to the ear)?
No, cefotaxime is not an ototoxic drug when given alone, but when given along with aminoglycoside antibiotics (gentamicin, tobramycin), it may increase ototoxicity

Q.Is cefotaxime bacteriostatic or bactericidal?
Cefotaxime is a bactericidal agent

Q.What organisms does cefotaxime cover?
Cefotaxime is active against Escherichia coli, group A and B streptococci, pseudomonas and staphylococcus bacteria. In some cases, Streptococcus pneumonia may show resistance to the drug. It may not be effective against methicillin- resistant Staphylococcus aureus (MRSA).

Sulbactam

Q.Is sulbactam a sulfa (sulfonamide) drug?
Sulbactam does not contain sulfa. It is a semisynthetic beta lactamase Inhibitor

Q.What is sulbactam sodium?
Sulbactam is a beta-lactamase inhibitor used as the sodium salt to increase the antibacterial activity of penicillins

Q.Is sulbactam safe?
Sulbactam is relatively safe if used at prescribed doses for the prescribed duration as advised by your doctor.

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Content on this page was last updated on 22 March, 2014, by Dr. Varun Gupta (MD Pharmacology)