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MD (Pharmacology), MBBS
Last updated:
27 Dec 2019 | 01:09 PM (IST)
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Cazat Injection


Overview

Introduction

Cazat Injection belongs to the general group of medicines called antineoplastics. It is used for the treatment of advanced prostate cancer. It works by interfering with the growth of cancer cells, which are eventually destroyed.

Cazat Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include Low red blood cell count, low platelet count, diarrhea, back pain, and hair loss. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, and physical examinations both before and during treatment with this medicine.

Uses of Cazat Injection

Side effects of Cazat Injection

Common
  • Vomiting
  • Back pain
  • Weakness
  • Low blood platelets
  • Hair loss
  • Abdominal pain
  • Loss of appetite
  • Anemia (low number of red blood cells)
  • Diarrhea
  • Stomatitis (Inflammation of the mouth)
  • Blood in urine
  • Constipation
  • Cough
  • Taste change
  • Breathing difficulty
  • Decreased white blood cell count (neutrophils)
  • Nausea

How to use Cazat Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cazat Injection works

Cazat Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Cazat Injection.
Pregnancy
CONSULT YOUR DOCTOR
Cazat Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
CONSULT YOUR DOCTOR
Cazat Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Cazat Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Cazat Injection is safe to use in patients with kidney disease. No dose adjustment of Cazat Injection is recommended.
Caution is advised in patients with severe kidney disease and end stage kidney disease as the information available is limited for use of this medicine in these patients.
Liver
CAUTION
Cazat Injection should be used with caution in patients with liver disease. Dose adjustment of Cazat Injection may be needed. Please consult your doctor.
Use of Cazat Injection is not recommended in patients with severe liver disease.

What if you forget to take Cazat Injection?

If you miss a dose of Cazat Injection, please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Cazat Injection
₹25000.0/ml of Injection
Cabaxan Injection
Intas Pharmaceuticals Ltd
₹7361.28/ml of Injection
save 56%
Kabanat Injection
Natco Pharma Ltd
₹8013.8/ml of Injection
save 52%
Procabazi 60mg/ml Injection
Glenmark Pharmaceuticals Ltd
₹7400/ml of Injection
save 56%
Jevtana Injection
Emcure Pharmaceuticals Ltd
₹66666/ml of Injection
300% costlier

Quick Tips

  • Inform your doctor if you have epilepsy (fit), problems with your liver, kidney or if you have undergone radiation treatment or have a history of bleeding of the stomach or intestine or alcohol dependency.
  • Always take cabazitaxel along with other steroid medications like prednisolone.
  • Inform your doctor if you are taking anti-inflammatory drugs such as aspirin, ibuprofen or drugs that affect blood-clotting such as warfarin, coumarin or clopidogrel before taking cabazitaxel.
  • Do not receive any vaccination while on cabazitaxel therapy.
  • Do not drive or operate heavy machinery while taking this drug as it may make you feel dizzy or tired.
  • Do not consume this drug if you are allergic to other taxanes, cabazitaxel or any of its ingredients.
  • If you are a male patient, you should seek advice on sperm conservation prior to treatment with cabazitaxel as the drug may affect male fertility.

Patient Concerns

arrow
I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.
Do i have prostrate cancer. Married but now having difficulty in having relation with wife. Penis not hard in the morning. Having problem with self spontaneous erection. Please help. God Bless.
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Not a symptom of prostate cancer
arrow
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User Feedback


FAQs

Q. Is Cazat a vesicant or chemotherapeutic drug?

Cazat is a chemotherapeutic drug (drug used for the management of cancer). It is, however, not a vesicant (drug which causes severe blisters on the skin).

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 176-78.
  2. Cabazitaxel. Oxford, Oxfordshire: Genzyme Therapeutics; 2011 [revised 03 Apr. 2017]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Cabazitaxel. Bridgewater, New Jersey: Sanofi-aventis; 2010. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Dr. Reddy's Laboratories Ltd., 8-2-337, Road No. 3, Banjara Hills, Hyderabad, Telangana 500034, INDIA
Best Price
₹20000
MRP25000  Get 20% OFF
1.5 ml in 1 vial
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