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MRP: Rs. 2797.62 for 1 vial(s) (45 ML injection each)
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Composition for CARBOTINAL

Carboplatin(450 mg)

food interaction for CARBOTINAL

alcohol interaction for CARBOTINAL

pregnancy interaction for CARBOTINAL

lactation interaction for CARBOTINAL

It can be taken with or without food, but it is better to take Carbotinal 450mg injection at a fixed time.
Interaction with alcohol is unknown. Please consult your doctor.
Carbotinal 450mg injection is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Carbotinal 450mg injection is probably unsafe to use during breastfeeding. Please consult your doctor.


Carboplatin(450 mg)


Carbotinal 450mg injection is medication used alone or in combination with other drugs in the treatment of advanced ovarian (organs where eggs are formed) cancer and in lung cancer when treatment with other medicines have failed. It is also sometimes used to treat cancer of bladder and uterus; head and neck; cervix and testicles; Wilms' tumor (a type of kidney cancer that occurs in children); certain types of brain tumors; neuroblastoma (a cancer that begins in nerve cells and occurs mainly in children); and retinoblastoma (cancer in the eye).

How it works

Carbotinal 450mg injection belongs to a class of medication called antineoplastic or alkalyting agents. It is a platinum-containing compound. Carbotinal 450mg injection kills cancer cells by binding to cell’s DNA and interfering with the repair mechanism of the cell at all stages of the cell cycle, eventually leading to cell death. It thereby slows down or stops the growth of cancer cells in the body.

Common side effects

Vomiting, Nausea, Pale colored skin, Application site itching, Constipation, Diarrhoea, Dizziness, Altered taste, Fainting, Fatigue, Weakness, Hair loss, Injection site redness, Injection site swelling, Injection site pain, Renal dysfunction, Sore mouth, Sore throat, Tingling sensation of extremity


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Expert advice for CARBOTINAL

  • Inform your doctor if you have a history of kidney (renal) disorder. 
  • Kidney and liver function will be monitored during carboplatin treatment.
  • Neurological and hearing assessments may be required on regular basis during treatment with high doses of carboplatin.
  • It is generally recommended that aluminium containing equipment not be used for delivering carboplatin.
  • Concurrent treatment with following medications is not recommended: amino glycoside, vancomycin, capreomycin and diuretics.
  • Allergic reactions (like hives; skin rash; itching; reddening of the skin; difficulty breathing or swallowing; dizziness; faintness; or fast heartbeat) may occur during therapy which will be duly managed by your doctor.
  • There might be low numbers of platelets or white blood cells during therapy and hence, frequent monitoring of blood cell counts and transfusions of the same may be required.
  • Call your doctor immediately if you experience any of the following during the therapy: fever, sore throat, chills, ongoing cough and congestion, or other signs of infection; unusual bleeding or bruising; black and tarry stools; red blood in stools; bloody vomit; vomited material that looks like coffee grounds.
  • Women who are planning to become pregnant should use two methods of contraception while on this therapy and 6 months after it.
  • Men who are going to use this therapy should not father a child while on this therapy and 6 months after stopping. They should also seek guidance and counselling on sperm conservation before taking this therapy.

Frequently asked questions for CARBOTINAL


Q. Is carboplatin a generic?
Yes, carboplatin is a generic platinum-based compound.
Q. Is carboplatin cell cycle specific?
No, carboplatin is not a cell cycle specific anticancer medication.
Q. Is carboplatin vesicant/cardio-toxic/ anthracycline?
No carboplatin is not cardio-toxic/ anthracycline/vesicant. 
Q. Is carboplatin FDA approved?
Yes carboplatin is an FDA approved drug.
Q. Is carboplatin used for breast cancer?
 It is used to treat advanced stage breast cancer.

Q. Is it a platinum based drug?
Yes carboplatin is a platinum based drug and is effectively used in combination with other drugs 
Q. Is carboplatin available in pill form?
No carboplatin is not available in pill form.
Q. Does carboplatin cause neuropathy/ hearing loss/ hair loss/ weight gain/ constipation/ leukemia?
Yes carboplatin is known to cause side effects like neuropathy, hearing loss, hair loss, weight gain, and constipation. Please inform your doctor about any side-effect that you may observe on taking this drug. Infertility while on therapy may be caused as a side effect of this drug but it may be reverse after stopping the therapy. Yes carboplatin may cause leukemia if it is used for a long duration.


Content on this page was last updated on 29 July, 2014, by Dr. Varun Gupta (MD Pharmacology)