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MD (Pharmacology), MBBS
Last updated
26 Sep 2022 | 04:35 PM (IST)

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Calutide 50 Tablet

Prescription Required
Manufacturer/ Marketer
SALT COMPOSITION
Storage
Store below 30°C
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Product introduction

Calutide 50 Tablet is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Calutide 50 Tablet should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Anemia (low number of red blood cells) is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes are some side effects which require immediate action. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.  You may be asked for regular monitoring of blood glucose level while on treatment.

Uses of Calutide Tablet

Benefits of Calutide Tablet

In Prostate cancer

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Calutide 50 Tablet decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side effects of Calutide Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Calutide

  • Anemia (low number of red blood cells)
  • Rash
  • Abdominal pain
  • Breast enlargement in male
  • Breast tenderness
  • Constipation
  • Decreased appetite
  • Decreased libido
  • Depression
  • Dizziness
  • Indigestion
  • Flatulence
  • Hot flashes
  • Increased liver enzymes
  • Nausea
  • Sleepiness
  • Weakness
  • Weight gain

How to use Calutide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Calutide 50 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Calutide Tablet works

Calutide 50 Tablet blocks the effect of the natural male hormones on the growth of prostate cells. Calutide 50 Tablet also blocks the undesired effects of androgens in females such as excessive hair growth and acne.

Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Calutide 50 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Calutide 50 Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Calutide 50 Tablet during breastfeeding is not available. Please consult your doctor.
Driving
SAFE
Calutide 50 Tablet does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Calutide 50 Tablet is safe to use in patients with kidney disease. No dose adjustment of Calutide 50 Tablet is recommended.
Liver
CAUTION
Calutide 50 Tablet should be used with caution in patients with liver disease. Dose adjustment of Calutide 50 Tablet may be needed. Please consult your doctor.
Regular monitoring of liver function tests is advisable while you are taking this medicine.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Calutide 50 Tablet
₹57.89/Tablet
Ablu 50mg Tablet
Neon Laboratories Ltd
₹19.76/tablet
66% cheaper
Bicatero 50mg Tablet
Hetero Drugs Ltd
₹35.93/tablet
38% cheaper
₹37.5/tablet
35% cheaper
Cosalon 50mg Tablet
Celon Laboratories Ltd
₹39/tablet
33% cheaper
Tabi Tablet
Dr Reddy's Laboratories Ltd
₹39.9/tablet
31% cheaper

Quick tips

  • You have been prescribed Calutide 50 Tablet for the treatment of prostate cancer.
  • Take it with or without food, preferably at the same time every day.
  • It may cause your skin to become light sensitive. Avoid direct exposure to excessive sunlight and use sunscreen when outdoors.
  • If you are diabetic, monitor your blood glucose regularly while taking Calutide 50 Tablet.
  • Your doctor may want you to have regular blood tests to monitor your liver function while you are taking this medicine. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
  • Do not stop taking the medication without talking to your doctor first.

Fact Box

Chemical Class
Trifluoromethylbenzenes Derivative
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Androgen receptor antagonist

Interaction with drugs

Taking Calutide with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Altrom, Cenorol, Cgtrom
Moderate
Brand(s): Cofarin, Sofarin, Warf
Moderate
Brand(s): Dindevan
Moderate

Patient concerns

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Is this can be taken as a substitute for calutide-50 ?
Dr. Rohan Khandelwal
Surgical Oncology
Sir, this is a drug for Prostate cancer. Can you share your reports, so that I can help you with some alternate treatment
I have problem of frequent urination at night. My father had same at his time.Doctor told me that I am having BPH.Also I went through PSA whose result is 1.8 increased prostate gland size is 40 which came in ultrasound report .When doctor did some test by inserting his finger in my rectal area I felt abnormal pain.doctor asked me to go for a culture test so as to check which can be the best medicine for BPH for me. Kindly suggest if it can be something else like prostate cancer.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
May not be prostate cancer, it is only begnin enlargement of prostate.
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User feedback


FAQs

Q. Can Calutide 50 Tablet cause infertility?

There is limited data to support that Calutide 50 Tablet causes infertility. Calutide 50 Tablet has been shown to affect fertility in animals and therefore it is assumed that it may cause fertility on humans. Some studies have shown that it affects spermatogenesis (origin and development of the sperm cells).

Q. What should I avoid while taking Calutide 50 Tablet?

Skin sensitivity has been observed in some patients while taking Calutide 50 Tablet. Therefore, you should avoid direct sun exposure, sunlamps, and tanning beds. It is advised to use a sunscreen during treatment with Calutide 50 Tablet.

Q. Is Calutide 50 Tablet a form of chemotherapy?

No, Calutide 50 Tablet is not a form of chemotherapy medicine, it is anti-androgen medicine. Androgens such as testosterone are natural male sex hormones. Calutide 50 Tablet works by blocking the effect of androgens (testosterone) in order to stop the growth and spread of cancer cells.

Q. Does Calutide 50 Tablet cause hair loss?

Yes, Calutide 50 Tablet may cause hair loss as it is a common side effect. However, this does not affect everyone. Consult your doctor, if hair loss is worrying you.

Q. What is Calutide 50 Tablet prescribed for?

Calutide 50 Tablet is used with another medication (gonadotropin-releasing hormone (GnRH) agonists; such as leuprolide or goserelin) to treat metastatic prostate cancer (prostate cancer that has spread to other parts of the body). Other than that, Calutide 50 Tablet has been effective in treating hirsutism in patients with polycystic ovarian disease, though this is not an approved use.

Q. When should I take Calutide 50 Tablet?

Calutide 50 Tablet should be taken at the same time every day either in the morning or in the evening. Take it exactly as directed by your doctor.

Q. Can Calutide 50 Tablet cause diarrhea?

Yes, Calutide 50 Tablet can cause diarrhea though it is rare. Generally, constipation is more common with this medicine. Consult your doctor if it worries you.

Q. How long do I need to take Calutide 50 Tablet?

Calutide 50 Tablet tablets should be taken continuously for a minimum of 2 years or until the disease persists. Do not stop taking it without consulting your doctor.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1766.
  2. Chrousos GP. The Gonadal Hormones & Inhibitors. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 724.
  3. Bicalutamide. Sellersville, PA: TEVA Pharmaceutical; 1995 [revised Jun. 2009]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Bicalutamide. Capability Green: AstraZeneca UK; 2000 [revised 08 Feb. 2018]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India
Expires on or after: May, 2023

A licensed vendor partner from your nearest location will deliver Calutide 50 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

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