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Bicalutamide is used in the treatment of prostate cancer

How it works

Bicalutamide works by blocking the effect of the natural male hormones on the growth of prostate cells. Bicalutamide also used in females to block the undesired effects of androgens like excessive hair growth and acne.

Common side effects

Nausea, Vomiting, Skin rash, Liver disorder, Abdominal pain, Anemia, Blood in urine, Chest pain, Constipation, Decreased libido, Decreased fertility, Depression, Dizziness, Dry skin, Shortness of breath, Worsening of a pre-existing breathing problem, Erectile dysfunction, Decreased red blood cell count, Hair loss, Hot flashes, Indigestion, Itching, Loss of appetite, Rash, Sleepiness, Swelling, Weakness, Weight gain, Yellow discoloration of skin, Yellow discoloration of eye

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Expert advice

  • Before taking bicalutamide, tell your doctor if you have any liver disease.
  • Bicalutamide may cause serious liver dysfunction (with symptoms of abdominal pain, anorexia, dark urine, fatigue, jaundice, nausea, vomiting). Stop taking Bicalutamide and call your doctor if you experience any such symptoms.
  • If you have an objective progression of disease together with elevated PSA, seek immediate medical advice, as you may have to stop bicalutamide treatment.
  • You should not take this medicine if you have rare hereditary problems of galactose intolerance, the Lapp lactase deficiency or glucose-galactose malabsorption. 
  • Take precautions as you may occasionally feel sleepy while on bicalutamide therapy. 
  • Avoid direct exposure to excessive sunlight or UV-light while you are taking bicalutamide.
  • Do not drink alcohol while on bicalutamide treatment as it may worsen the side effects of this medication.

Frequently asked questions


Q. Is Bicailutamide a chemotherapy drug?
No. Bicailutamide is not a chemotherapy drug

Q. Is bicalutamide a hormone/Lower PSA Levels?
Bicalutamide is not a hormone however due to its anti-androgen properties, it lowers PSA.

Content on this page was last updated on 28 December, 2016, by Dr. Varun Gupta (MD Pharmacology)