Bific 300mg Injection

Biapenem (300mg)

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Bific 300mg Injection is an antibiotic that is used to treat complicated urinary tract infections. It works by killing the bacteria thereby stopping their growth. The dose of this medication will depend on the age and symptoms of individual patients.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 05 Jan 2026 | 03:58 PM (IST)

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Biapenem (300mg)

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General Information

Contains

Biapenem (300mg)

Marketer

Gufic Bioscience Ltd

The content is shown in English

Product introduction

Bific 300mg Injection is given as an injection by a doctor or a nurse; do not self-administer. It should be used for the minimum period necessary to prevent the development of resistant bacteria.

The most common side effects of this medicine include rash; pruritus; eosinophilia; gastrointestinal distress (diarrhea, nausea); and increased alanine transaminase, aspartate transaminase, and alkaline phosphatase. These side effects are usually temporary and go away as your body adjusts to the medicine. However, consult your doctor if the side effects persist or worsen.

Bific 300mg Injection should be used with caution in patients who have a known history of allergy to other antibiotics (such as carbapenems, penicillins, and cephalosporins) and in those with a history of epilepsy and other central nervous system disorders. Let your doctor know if you are receiving sodium valproate as part of your medication, as Bific 300mg Injection may decrease blood levels of valproic acid and cause epileptic seizures. While on treatment with this medicine, your doctor may also advise blood tests to monitor your kidney function. Pregnant and breastfeeding women should also consult their doctors before using this medicine.

Uses of Bific Injection

Treatment of Urinary tract infections (UTIs)

Benefits of Bific Injection

Treatment of Urinary tract infections (UTIs)
Bific 300mg Injection helps treat urinary tract infections (UTIs) by targeting and eliminating a wide range of bacteria, including strains that may not respond to commonly used antibiotics. It works quickly to reduce infection-related symptoms such as fever, pain, and urinary discomfort, allowing faster recovery. The medicine is especially useful in moderate to severe UTIs or when the infection is caused by resistant organisms, helping prevent complications and supporting the body’s return to normal urinary function.

Side effects of Bific Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Bific

Rash
Itching
Diarrhea
Nausea
Increased alanine aminotransferase
Increased aspartate aminotransferase
Increased alkaline phosphatase level in blood
Increased white blood cell count (eosinophils)

How to use Bific Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Bific Injection works

Bific 300mg Injection inhibits bacterial cell wall synthesis and kills the bacteria.

All substitutes for Bific 300mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Inform your doctor if you have a history of epilepsy and are on medications like sodium valproate because Bific 300mg Injection may reduce the levels of valproic acid and also result in the recurrence of epileptic seizures.
Let your doctor know if you have severe kidney disease before starting the treatment with Bific 300mg Injection.
Along with taking this medicine, maintain personal hygiene and drink an adequate amount of water.
Inform your doctor if you have a history of epilepsy and are on medications like sodium valproate because Bific 300mg Injection may reduce the levels of valproic acid and also result in the recurrence of epileptic seizures.
Let your doctor know if you have severe kidney disease before starting the treatment with Bific 300mg Injection.
Along with taking this medicine, maintain personal hygiene and drink an adequate amount of water.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Bific 300mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Bific 300mg Injection during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Bific 300mg Injection during breastfeeding is not available. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Bific 300mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Bific 300mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Bific 300mg Injection in patients with liver disease.

Fact Box

Chemical Class

Thienamycins

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Carbapenems

Related lab tests

Culture Urine

Urine Routine & Microscopy

References

Vora A, Tiwaskar M. Biapenem. J Assoc Physicians India. 2022 Jan;70(1):11-12. [Accessed 05 Jan. 2026]. Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Gufic Bioscience Ltd
Address: 37,1st Floor, Kamala Bhavan II, Swami Nityanand Road, Andheri (East), Mumbai - 400 069. (INDIA)

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Bific 300mg Injection

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General Information

Contains

Marketer

Product introduction

Uses of Bific Injection

Benefits of Bific Injection

Side effects of Bific Injection

How to use Bific Injection

How Bific Injection works

All substitutes for Bific 300mg Injection

Biastrong 300mg Injection

Biapride 300mg Injection

Berrobe 300mg Injection

Bianem 300mg Injection

Lapenem 300mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Culture Urine

Urine Routine & Microscopy

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests