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Written By
BCMAS, Pharm.D
Reviewed By
MD (Pharmacology), MBBS
Last updated on:
28 Nov 2018 | 10:42 AM (IST)
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Atline-P 12.5mg/5mg Tablet


Uses of Atline-P Tablet

Atline-P Tablet side effects

  • Constipation
  • Difficulty in urination
  • Weight gain
  • Confusion
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Uncoordinated body movement
  • Depression
  • Memory impairement

How to use Atline-P Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Atline-P 12.5mg/5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Atline-P Tablet works

Atline-P 12.5mg/5mg Tablet is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Atline-P Tablet related warnings

Atline-P 12.5mg/5mg Tablet may cause excessive drowsiness and calmness with alcohol.
Atline-P 12.5mg/5mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Atline-P 12.5mg/5mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Do not drive unless you are feeling well.
As Atline-P 12.5mg/5mg Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Atline-P 12.5mg/5mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Atline-P 12.5mg/5mg Tablet may not be needed in these patients. Please consult your doctor.
Atline-P 12.5mg/5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Atline-P 12.5mg/5mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Atline-P 12.5mg/5mg Tablet
save 6%
Amixide-H Tablet
Sun Pharmaceutical Industries Ltd
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Aculip H 12.5 mg/5 mg Tablet
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Amitone Plus Tablet
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Patient Concerns

Questions Related to Atline-P

Fluctuate b. P and mild depressionPlz prescribe specific medicine
Dr. Saurav Arora
Please elaborate your symptoms, history, treatment and investigations done.
Hello doctor I am 70 years old HAVING depression problem since 2004 but now I am fine only having sometime high bp and low too as well as facing ohsto arthritis and cervical last few months and I am taking EZITAM-1,SADROX 12.5CR ,TRUACE-P,OSTEOFOS 70,APINE-AT.5mg ,SHELCAL-500,Rozvit,rebicip-20,ECOSPRIN-AV75 all once a day BUT I feel Noshiya in evening what should I do.should I stop any.Please suggest.thanks
Dr. Vikas Sharma
show to gastro for nausea
Do you have any questions related to Atline-P 12.5mg/5mg Tablet?


Q. What are the instructions for storage and disposal of Atline-P?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Are there any important warnings associated with use of Atline-P?

During the first few months of treatment, Atline-P may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

Q. Can I stop taking Atline-P when my symptoms are relieved?

No, you should continue to take Atline-P, even if you feel well. If you stop Atline-P suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

Q. How to manage weight gain associated with the use of Atline-P?

There are reports which suggest that the use of Atline-P can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

Q. Can the use of Atline-P cause sleepiness?

Yes, Atline-P can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Atline-P affect my sexual life?

The use of Atline-P can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Atline-P?

No, do not drink alcohol while you are taking Atline-P. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Atline-P.

Q. Can the use of Atline-P change the color of urine?

Yes, Atline-P can the change the color of the urine to blue or green. This change of color is expected while using Atline-P, and it is not harmful. Your urine color becomes normal once you stop taking Atline-P.

Q. How long does Atline-P take to work?

Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Atline-P, although some people will start to feel better sooner. When taking Atline-P, it is important to give it time to work.

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Related Ayurvedic Ingredients

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
  1. DailyMed. Chlordiazepoxide and amitriptyline hydrochloride. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Amitriptyline. North Harrow, Middlesex: Accord Healthcare Limited; 2018. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. MedlinePlus. Chlordiazepoxide. [Accessed 10 Apr. 2019] (online) Available from:External Link
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