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Written By
BCMAS, Pharm.D
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MD (Pharmacology), MBBS
Last updated on:
16 Oct 2019 | 01:31 PM (IST)
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Amixide 10mg Tablet


Overview

Introduction

Amixide 10mg Tablet is a combination of two medicines. It is used in the treatment of depression associated with anxiety. It helps in regulating mood and to reduce anxiety.

Amixide 10mg Tablet is taken with or without food. However, it is advisable to take it at a fixed time each day to maintain consistent level of medicine in the blood. In case you miss a dose of this medicine, take it as soon as you remember. Never skip any dose and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to the doctor as it may worsen your symptoms. Taking this medicine for long time may require regular monitoring of blood and liver functions.

Some common side effects of this medicine include insomnia, agitation, anxiety and a feeling of worthlessness. This medicine may cause weight loss. So, in case you lose weight, consult a dietitian for dietary supplement or try to increase your food portion. Remember to inform your doctor if you develop any unusual changes in mood as it may lead to suicidal thoughts.

Uses of Amixide Tablet

Amixide Tablet side effects

Common
  • Constipation
  • Difficulty in urination
  • Weight gain
  • Confusion
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Tiredness
  • Blurred vision
  • Dryness in mouth
  • Increased heart rate
  • Uncoordinated body movement
  • Depression
  • Memory impairement

How to use Amixide Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Amixide 10mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Amixide Tablet works

Amixide 10mg Tablet is a combination of two medicines: Amitriptyline and Chlordiazepoxide, which treats depression. Amitriptyline is a tricyclic antidepressant which increases the levels of chemical messengers in the brain that help in regulating the mood and treat depression. Chlordiazepoxide is a benzodiazepine (BZD) which works by increasing the action of GABA, a chemical messenger which suppresses the abnormal and excessive activity of the nerve cells in the brain.

Amixide Tablet related warnings

Alcohol
UNSAFE
It is unsafe to consume alcohol with Amixide 10mg Tablet
Pregnancy
CONSULT YOUR DOCTOR
Amixide 10mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Lactation
CONSULT YOUR DOCTOR
Amixide 10mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Amixide 10mg Tablet may cause side effects which could affect your ability to drive.
As Amixide 10mg Tablet may make you feel drowsy or affect your concentration and this may affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Amixide 10mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Amixide 10mg Tablet may not be needed in these patients. Please consult your doctor.
Liver
CAUTION
Amixide 10mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Amixide 10mg Tablet may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Amixide 10mg Tablet
₹5/Tablet
₹5.2/Tablet
4% costlier
₹2.42/Tablet
save 52%
Mytrip Plus Tablet
Mayflower India
₹3.1/Tablet
save 38%
Relidep Plus 25 mg/10 mg Tablet
Reliance Formulation Pvt Ltd
₹4.1/Tablet
save 18%
Aculip 25 mg/10 mg Tablet
Shine Pharmaceuticals Ltd
₹4.35/Tablet
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Patient Concerns

Questions Related to Amixide

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Patient had problem of depression some years ago. He consulted to a psychiatrist. He asked to take amixide tablet daily for three months but the patient didn't reached the doctor . Now he is continuing the medicine. Now he is unable to leave taking medicine. Now what should we do . please help us
Dr. Ambrish Dharmadhikari
Mental Wellness
Sometime, patient continue tablets and body becomes habitual to these tablets. You need to see psychiatrist and change tablets. With which patient will be able to leave current tablet and gradually under supervision of doctor, he shall be off medications. Dr. Surjit Prasad +91 80512 13044 Practices at Kanke Raod, Ranchi. He is my colleague, I would brief about you to him. Please see him, he shall help you in all means.
how to get free from this disease depression. without taking these medicines nexito and amixide I can't sleep . taking from 1half yes. please
Dr. Venkatraju Kalidindi
Psychiatrist
Dear 1mg user, please come to online counselling audio(phone) chat so that i can take your history and suggest you best life style, Pay Rs 99 and call me on my phone www.dontfeel.com
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User Feedback


FAQs

Q. What are the instructions for storage and disposal of Amixide?

Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Q. Are there any important warnings associated with use of Amixide?

During the first few months of treatment, Amixide may increase suicidal thoughts or actions in some patients. Patients having mood or behavioral disorder have a high risk of developing suicidal thoughts and actions. You should pay close attention and report your doctor of any such behavior or mood changes. Make sure that you visit the doctor for the scheduled follow-up appointments.

Q. Can I stop taking Amixide when my symptoms are relieved?

No, you should continue to take Amixide, even if you feel well. If you stop Amixide suddenly, serious withdrawal symptoms may occur. Consult your doctor if the symptoms are relieved, he might decrease your dose gradually.

Q. How to manage weight gain associated with the use of Amixide?

There are reports which suggest that the use of Amixide can cause weight gain. If you maintain good eating habits and exercise regularly, you might not gain any weight. An important to remember is that it is easier to prevent weight gain than losing increased weight.

Q. Can the use of Amixide cause sleepiness?

Yes, Amixide can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.

Q. Can the use of Amixide affect my sexual life?

The use of Amixide can affect the sexual life of both men and women. Most commonly caused problems are decreased sexual desire, erectile dysfunction (inability to develop or maintain erection during the sexual activity) and inability to reach orgasm. It can also cause a decrease in satisfaction and cause discomfort while having sex. If you experience these problems, discuss with your doctor.

Q. Can I drink alcohol while taking Amixide?

No, do not drink alcohol while you are taking Amixide. Drinking alcohol can increase the severity of drowsiness or sleepiness caused by Amixide.

Q. Can the use of Amixide change the color of urine?

Yes, Amixide can the change the color of the urine to blue or green. This change of color is expected while using Amixide, and it is not harmful. Your urine color becomes normal once you stop taking Amixide.

Q. How long does Amixide take to work?

Everybody responds differently to the treatment. In general, it can take several weeks to feel the full benefits of Amixide, although some people will start to feel better sooner. When taking Amixide, it is important to give it time to work.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. DailyMed. Chlordiazepoxide and amitriptyline hydrochloride. [Accessed 10 Apr. 2019] (online) Available from:External Link
  2. Amitriptyline. North Harrow, Middlesex: Accord Healthcare Limited; 2018. [Accessed 10 Apr. 2019] (online) Available from:External Link
  3. MedlinePlus. Chlordiazepoxide. [Accessed 10 Apr. 2019] (online) Available from:External Link
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