Medicine Overview of Almantin Tablet
Almantin 5mg Tablet is used in the treatment of Alzheimer's disease
It should be used in patients with moderate to severe Alzheimer's disease.
Dizziness, Headache, Confusion, Constipation.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Almantin 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
Memory loss in Alzheimer’s disease is due to an imbalance of chemical messengers in the brain. Almantin 5mg Tablet works by blocking the action of glutamate, a chemical messenger involved in the transmission of nerve signals.
In Depth Information on Almantin Tablet
Almantin Tablet related warnings
Interaction with alcohol is unknown. Please consult your doctor.
Almantin 5mg Tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
No information is available on the use of Almantin 5mg Tablet during lactation. Please consult your doctor.
Almantin 5mg Tablet may cause side effects which could affect your ability to drive.
Almantin 5mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment of Almantin 5mg Tablet may be needed. Please consult your doctor.
Almantin 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Almantin 5mg Tablet may be needed. Please consult your doctor.
Limited information is available on the use of Almantin 5mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
If you miss a dose of Almantin 5mg Tablet, skip it and continue with your normal schedule. Do not double the dose.
Frequently asked questions about Almantin Tablet
A psychotropic drug is a medicine affecting the mind, emotions, and behaviour. Almantin has a beneficial effect on the behavioural symptoms of patients with moderate to severe Alzheimer's Disease. Therefore it is considered as a psychotropic agent.
No. Almantin is not a narcotic. It does not have habit forming potential.
No. Mood stabilisers are used to treat mania and bipolar disorder. Almantin is not approved for these conditions yet, although studies are going on for the role of Almantin in these diseases also.
No. Almantin does not fit in the generally accepted "Nootropic" descriptor for healthy people. Nootropics are drugs which increase cognition/ motivation/ creativity in healthy individuals. Almantin, on the other hand, improves cognition in patients with Alzheimer's Disease.
Q. Is Almantin a cholinesterase inhibitor?
No. Almantin does not function by inhibiting the cholinesterase enzyme found in the endings of nerve cells. Rather, it acts by preventing the toxicity of an excitatory substance called glutamate in the brain.
Yes. Almantin acts as an antagonist at the NMDA receptor. This is the receptor in the brain through which glutamate, an excitatory substance, damages the nerve cells in the brain, which is found in Alzheimer's disease.
Cmax (Peak plasm concentration) of Almantin is 35-40 ng/ml.
Q. Can I take Almantin with vitamin D?
It has been reported in some studies that a combination of Almantin and Vitamin D improves cognition in Alzheimer's Disease. However, more studies are required to confirm this finding.
Q. Can I take Almantin with vitamin E?
Some studies have reported that among patients with mild to moderate Alzheimer's disease, taking alpha-tocopherol (Vitamin E) with Almantin slows the progressive functional decline. However, more studies are required to confirm this finding.
Almantin is started when a person starts suffering from moderate to severe Alzheimer's Disease and has failed other options. Despite years of research for mild Alzheimer's Disease, Almantin has not been found to be useful in it.
Almantin is prescribed to improve the cognitive (memory) function in patients with Alzheimer's Disease when other treatment options like cholinesterase enzyme inhibitors have failed.
Q. What is the interaction of Almantin with metformin?
The interaction between Almantin and Metformin is minor. Almantin oral increases the level or effect of metformin by nonacidic drugs competing for the same pathway through the kidney.
Q. What is the interaction of Almantin with warfarin?
No known interaction between Almantin and Warfarin has been found.
The role of Almantin in Lewy Body Dementia (LBD) is controversial. Some studies suggest that it is safe and efficacious in this disease whereas others have shown exacerbation of LBD due to Almantin. Almantin is not approved for use in Lewy Body Dementia.
Q. Can Almantin combined with donepezil?
A combination of Almantin and Donepezil can be given in moderate to severe Alzheimer's Disease. It has been shown that the combination may have additive effects i.e. effects of both drugs are added when given together in some studies.
Q. Can Almantin be used with rivastigmine?
Almantin in combination with rivastigmine is safe and beneficial in patients with Alzheimer's Disease. Patients have improvement or stabilisation on dual therapy.
Almantin is not indicated for use in chronic pain. It has been proposed as a medication for the treatment of neuropathic pain for its mechanism, safety, lack of serious adverse effects, and the relatively rapid onset of action. However, studies have not been promising so far and its routine use in neuropathic pain is not currently recommended.
Almantin is not indicated for use in Opioid withdrawal. In a number of small studies, it has been seen that Almantin decreased the expression of opioid physical dependence in humans but there is a need for more studies in this field.
Almantin has failed to demonstrate clinical efficacy in autism. Studies are currently in progress for other clinical applications.
Almantin has failed to demonstrate clinical efficacy in vascular dementia although it was well-tolerated.
One of the following vendor pharmacies will deliver Almantin 5mg Tablet: PLT, OLT, AGT, MSD, SWP, MPC, PNT, BBS, TNH, GBL, DPP, SWA, NNH, HPC, RSS, DDR, RKS, SCH, STA, DLP, ADT, SRG, MAX, MOM, CLT, ZVP, BMJ, SHD, JMJ, BIO, OIP, IPL, ENP, INC, SVH, OHM, RUS, SYN, WSI, TRP, JIV, AYU, RWP, GTC, GNC, PVP, AAY, EMB, SAT, HGI, ATL, SAF, RPP, NDP, SDM, BTM, PTI, HBV, TOM, NSL, VRS, HMP, WHL, RHW, ANT, HAT, LHA, SSA, SBA, RJH, MDO, ABP, BSN, PEN, MAK, 9T9, JVO, KHH, FGH, RHL, THP, DYG, ARD, GPT, OWP, BAL, ZEL, GPP, SBL, HIP, PPR, NWP, BHP, DPL, PRN, LCC, AVN, IAD, NVY, GTK, MLC, DHR, UMP, PWN, AMR, NVL, RSA, USF, ATP, SJP, SHP, NXG, NTB, DFP, MAM, HEX, MMS, SGC, JVN, DGN, AAR, BDN, EQN