Afamac 40 Tablet

Afatinib dimaleate (40mg)

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required

Afamac 40 Tablet is used in the treatment of non-small cell lung cancer. It is used in the treatment of adult patients who have certain mutations of epidermal growth factor receptor (EGFR).

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 16 Apr 2026 | 03:24 PM (IST)

₹4029 MRP ₹468614% off

Gurgaon

Afamac 40 Tablet is currently sold out

Same composition alternative:

Afayro 40 Tablet

₹4738~~₹5156.25~~

Available alternative from Glenmark Pharmaceuticals

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Afamac 40 Tablet

bottle of 28 tablets

₹4029

~~₹4686~~

Same composition

Afayro 40 Tablet

strip of 28 tablets

Afatinib dimaleate (40mg)

by Glenmark Pharmaceuticals Ltd

Get by Thu, 30 Apr

₹4738

₹143.82 per tablet

₹4027

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General Information

Contains

Afatinib dimaleate (40mg)

Marketer

Admac Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Afamac 40 Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include diarrhea, rash, dry skin, and nausea. Diarrhea can be serious sometimes so take medicine to treat it as prescribed by the doctor or stay hydrated. Your doctor may advise for some blood tests while you are taking this medicine. It may also make your skin sensitive to the sun, so use sunscreen and wear protective clothing if you have to be in sunlight. Inform your doctor if you notice pain or redness in the eye or dry eye.

Before taking it, tell your doctor if have a breathing problem, liver, or kidney problems, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by females during treatment is important to avoid pregnancy.

Uses of Afamac Tablet

Non-small cell lung cancer

Benefits of Afamac Tablet

Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Afamac 40 Tablet helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Afamac Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Afamac

Itching
Stomatitis (Inflammation of the mouth)
Nail disorder
Diarrhea
Rash
Dry skin
Nausea
Vomiting
Loss of appetite

How to use Afamac Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afamac 40 Tablet is to be taken on an empty stomach.

How Afamac Tablet works

Afamac 40 Tablet is an anti-cancer medication. It works by binding and inhibiting the enzyme receptors (EGFR, HER2, and HER4) that are responsible for the growth of cancer cells. Hence, resulting in the downregulation of signaling pathways. This is how it to stop or slow the spread of cancer.

All substitutes for Afamac 40 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

You have been prescribed Afamac 40 Tablet for the treatment of certain type of lung cancer (non-small cell lung cancer).
Take Afamac 40 Tablet on an empty stomach at least 1 hour before a meal or 2 hours after a meal.
Diarrhea is common with Afamac 40 Tablet and may sometimes be severe. Your doctor may prescribe medicines to treat diarrhea. Stay hydrated and take this medicine exactly as directed.
Afamac 40 Tablet can make your skin sensitive to the sun. Limit your time in the sun. Use sunscreen and wear protective clothing if you have to be in sunlight.
Afamac 40 Tablet can cause redness, rash, and acne. Get treatment for skin reactions as soon as you notice them.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Afamac 40 Tablet is used for the treatment of thyroid cancer.
Take it with or without food, preferably at the same time each day.
Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.

Safety advice

Alcohol

SAFE

Consuming alcohol with Afamac 40 Tablet does not usually cause any harmful side effects.

Pregnancy

UNSAFE

Afamac 40 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Afamac 40 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Afamac 40 Tablet may cause temporary visual disturbances. Do not drive until your vision is clear.

Kidney

CAUTION

Afamac 40 Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Afamac 40 Tablet is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.

Interaction with drugs

Taking Afamac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Amiodarone (Oral Route)

If concurrent use is essential, ensure a gap of at least 12 hours between taking Afatinib dimaleate and Amiodarone. Watch out for symptoms of Afatinib dimaleate side effects such as headache, fatigue, nausea, drowsiness, weight gain, acne or muscle pain and consult your doctor if you experience them. They may adjust the dose of Afatinib dimaleate accordingly. Amiodarone may raise blood levels of Afatinib dimaleate.

Moderate

Amiodarone (Injection Route)

Moderate

Azithromycin (Oral Route)

If concurrent use is essential, ensure a gap of at least 12 hours between taking Afatinib dimaleate and Azithromycin. Watch out for symptoms of Afatinib dimaleate side effects such as headache, fatigue, nausea, drowsiness, weight gain, acne or muscle pain and consult your doctor if you experience them. They may adjust the dose of Afatinib dimaleate accordingly. Azithromycin may raise blood levels of Afatinib dimaleate.

Moderate

Azithromycin (Injection Route)

Moderate

Azithromycin (Oral Route)

Frequently asked questions

Is Afamac 40 Tablet an immunotherapy or chemotherapy?

Afamac 40 Tablet is neither an immunotherapy nor a conventional chemotherapy. It belongs to kinase inhibitors class of anti-cancer medicines. It works by blocking a group of proteins. These proteins are known to be involved in the growth and spread of cancer cells. By blocking the activity of these proteins, Afamac 40 Tablet stops the cancer cells from growing and multiplying.

How long does it take for Afamac 40 Tablet to work?

The peak levels of Afamac 40 Tablet are reached 2-5 hours after taking it. However, it may take weeks or months to see a noticeable change in the progression of cancer. The symptoms may improve visibly, but the effectiveness of Afamac 40 Tablet can be confirmed only after determining certain parameters.

How should I take Afamac 40 Tablet?

Afamac 40 Tablet is taken by mouth without food, at least 1 hour before or 3 hours after meals. Swallow the complete tablet with water without crushing or breaking it. Take this medicine once daily at about the same time each day. This will make it easier to remember to take this medicine. If you have difficulty in swallowing the tablet, dissolve it in a glass of water. Do not use any other liquid instead of water. Drop the tablet into the water without crushing it and stir occasionally for up to 15 minutes until the tablet is broken up into very small particles. Drink the liquid straight away. Then refill the glass with water and drink it to make sure all medicine is taken.

Does Afamac 40 Tablet have any effect on fertility?

Afamac 40 Tablet may decrease fertility in both men and women Therefore, if you have any concerns regarding fertility, talk to your doctor who might suggest sperm or egg preservation before starting treatment.

Can Afamac 40 Tablet be given along with chemotherapy?

There are no supporting studies to suggest that Afamac 40 Tablet can be used along with other chemotherapy medicines. Afamac 40 Tablet is used to treat specific type of lung cancer when the prior chemotherapy has been insufficient.

Can Afamac 40 Tablet cure lung cancer?

No, Afamac 40 Tablet cannot cure lung cancer, but it prolongs the survival of the patient. It may also reduce the size of the tumor.

What should I avoid while taking Afamac 40 Tablet?

You should avoid sun exposure as Afamac 40 Tablet can make your skin sensitive to the sun. You may get a severe sunburn or may develop rash or acne or it may get worsened. Therefore, use sunscreen and wear a hat before moving out in the sun. Wear clothes that cover your skin if you have to go out in the sun.

Can I do something if I get diarrhea due to Afamac 40 Tablet?

Diarrhea is a very common side effect of Afamac 40 Tablet. Severe diarrhea can cause excessive loss of body fluids (dehydration) and kidney problems that can sometimes lead to death. Start drinking plenty of fluids at the first signs of diarrhea and contact your doctor immediately. The doctor will start the appropriate antidiarrheal treatment (e.g. loperamide) as soon as possible. The doctor may also reduce your dose or discontinue the therapy if you develop severe diarrhea.

Fact Box

Chemical Class

Quinazolinamines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Afamac 40 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Afamac Tablet

Benefits of Afamac Tablet

Side effects of Afamac Tablet

How to use Afamac Tablet

How Afamac Tablet works

All substitutes for Afamac 40 Tablet

Afasted 40mg Tablet

Afayro 40 Tablet

Afmed 40mg Tablet

Afanat 40 Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Azithromycin (Oral Route)

Azithromycin (Injection Route)

Azithromycin (Oral Route)

Frequently asked questions

Is Afamac 40 Tablet an immunotherapy or chemotherapy?

How long does it take for Afamac 40 Tablet to work?

How should I take Afamac 40 Tablet?

Does Afamac 40 Tablet have any effect on fertility?

Can Afamac 40 Tablet be given along with chemotherapy?

Can Afamac 40 Tablet cure lung cancer?

What should I avoid while taking Afamac 40 Tablet?

Can I do something if I get diarrhea due to Afamac 40 Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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