Medicine Overview of Admenta Tablet
Uses of Admenta Tablet
Admenta 5mg Tablet is used in the treatment of Alzheimer's disease
It should be used in patients with moderate to severe Alzheimer's disease.
It should be used in patients with moderate to severe Alzheimer's disease.
Side effects of Admenta Tablet
Dizziness, Headache, Confusion, Constipation.
How to use Admenta Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. It can be taken with or without food, but it is better to take Admenta 5mg Tablet at a fixed time.
How Admenta Tablet works
Memory loss in Alzheimer’s disease is due to an imbalance of chemical messengers in the brain. Admenta 5mg tablet works by blocking the action of glutamate, a chemical messenger involved in the transmission of nerve signals.
In Depth Information on Admenta Tablet
Expert advice for Admenta Tablet
- Admenta slows down the progression of the disease; it doesn't stop or reverse it.
- Inform your doctor if you have ever been diagnosed with any heart problems (high blood pressure, heart attack, heart failure, slow or irregular heart rate).
- Inform your doctor if you have ever been diagnosed with any epileptic seizures. Admenta may raise the chances of seizure if you had in the past.
- Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
Special precautions for Admenta 5mg Tablet
Interaction with alcohol is unknown. Please consult your doctor.
Admenta 5mg Tablet is probably safe to use during pregnancy.+more
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor....
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
No information is available on the use of Admenta 5mg Tablet+more
during lactation. Please consult your doctor....
Admenta 5mg Tablet may cause side effects which could affect your ability to drive.
Admenta 5mg Tablet should be used with caution in patients w+more
ith severe kidney disease. Dose adjustment of Admenta 5mg Tablet may be needed. Please consult your doctor....
Admenta 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Admenta 5mg Tablet may be needed. Please consult your doctor.+more
Limited information is available on the use of Admenta 5mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease....
Limited information is available on the use of Admenta 5mg Tablet in these patients. No dose adjustment is recommended in patients with mild to moderate liver disease.
If you miss a dose of Memantine, skip it and continue with your normal schedule. Do not double the dose.
Frequently asked questions for Admenta 5mg Tablet
Frequently asked questions for Memantine
A psychotropic drug is a medicine affecting the mind, emotions, and behaviour. Admenta has a beneficial effect on the behavioural symptoms of patients with moderate to severe Alzheimer's Disease. Therefore it is considered as a psychotropic agent.
No. Admenta is not a narcotic. It does not have habit forming potential.
No. Mood stabilisers are used to treat mania and bipolar disorder. Admenta is not approved for these conditions yet, although studies are going on for the role of Admenta in these diseases also.
No. Admenta does not fit in the generally accepted "Nootropic" descriptor for healthy people. Nootropics are drugs which increase cognition/ motivation/ creativity in healthy individuals. Admenta, on the other hand, improves cognition in patients with Alzheimer's Disease.
Q. Is Admenta a cholinesterase inhibitor?
No. Admenta does not function by inhibiting the cholinesterase enzyme found in the endings of nerve cells. Rather, it acts by preventing the toxicity of an excitatory substance called glutamate in the brain.
Yes. Admenta acts as an antagonist at the NMDA receptor. This is the receptor in the brain through which glutamate, an excitatory substance, damages the nerve cells in the brain, which is found in Alzheimer's disease.
Cmax (Peak plasm concentration) of Admenta is 35-40 ng/ml.
Q. Can I take Admenta with vitamin D?
It has been reported in some studies that a combination of Admenta and Vitamin D improves cognition in Alzheimer's Disease. However, more studies are required to confirm this finding.
Q. Can I take Admenta with vitamin E?
Some studies have reported that among patients with mild to moderate Alzheimer's disease, taking alpha-tocopherol (Vitamin E) with Admenta slows the progressive functional decline. However, more studies are required to confirm this finding.
Admenta is started when a person starts suffering from moderate to severe Alzheimer's Disease and has failed other options. Despite years of research for mild Alzheimer's Disease, Admenta has not been found to be useful in it.
Admenta is prescribed to improve the cognitive (memory) function in patients with Alzheimer's Disease when other treatment options like cholinesterase enzyme inhibitors have failed.
Q. What is the interaction of Admenta with metformin?
The interaction between Admenta and Metformin is minor. Admenta oral increases the level or effect of metformin by nonacidic drugs competing for the same pathway through the kidney.
Q. What is the interaction of Admenta with warfarin?
No known interaction between Admenta and Warfarin has been found.
The role of Admenta in Lewy Body Dementia (LBD) is controversial. Some studies suggest that it is safe and efficacious in this disease whereas others have shown exacerbation of LBD due to Admenta. Admenta is not approved for use in Lewy Body Dementia.
Q. Can Admenta combined with donepezil?
A combination of Admenta and Donepezil can be given in moderate to severe Alzheimer's Disease. It has been shown that the combination may have additive effects i.e. effects of both drugs are added when given together in some studies.
Q. Can Admenta be used with rivastigmine?
Admenta in combination with rivastigmine is safe and beneficial in patients with Alzheimer's Disease. Patients have improvement or stabilisation on dual therapy.
Admenta is not indicated for use in chronic pain. It has been proposed as a medication for the treatment of neuropathic pain for its mechanism, safety, lack of serious adverse effects, and the relatively rapid onset of action. However, studies have not been promising so far and its routine use in neuropathic pain is not currently recommended.
Admenta is not indicated for use in Opioid withdrawal. In a number of small studies, it has been seen that Admenta decreased the expression of opioid physical dependence in humans but there is a need for more studies in this field.
Admenta has failed to demonstrate clinical efficacy in autism. Studies are currently in progress for other clinical applications.
Admenta has failed to demonstrate clinical efficacy in vascular dementia although it was well-tolerated.
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