Acalnib 100mg Capsule

Acalabrutinib (100mg)

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Acalnib 100mg Capsule is used to treat certain types of blood cancer such as mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. It works by blocking a protein that helps cancerous blood cells grow and survive, which helps slow the disease.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Sep 2026 | 01:02 AM (IST)

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General Information

Contains

Acalabrutinib (100mg)

Marketer

Hetero Healthcare Limited

The content is shown in English

Product introduction

Acalnib 100mg Capsule is taken orally, preferably with food or between meals. It should be used in the dose and duration prescribed by your doctor. It is advised to take this medicine at a fixed time and for as long as the doctor prescribes to avoid missing a dose. It may take several weeks or months for you to see or feel the benefits.

The most common side effects of Acalnib 100mg Capsule include anemia, neutropenia, upper respiratory tract infection, thrombocytopenia, headache, diarrhea, and musculoskeletal pain. If these bother you or appear serious, let your doctor know as they might suggest ways of reducing or preventing these side effects.

Inform your doctor if you have a medical history of bleeding disorders, heart or liver disease, radiation treatment, or any infection. The risk of bleeding may increase if the patient is taking a blood thinner medicine along with Acalnib 100mg Capsule. Many other medicines can affect or be affected by this medicine, so let your doctor know of all the medications you are using. Inform the doctor immediately if unusual bruising or bleeding or dark, tarry, or bloody stools and sore throat are noticed.

This medicine is known to reduce the number of blood cells in your blood, thereby increasing the susceptibility to infections. Regular blood tests are required to check the blood cell count along with the kidneys, liver, and heart functions during the treatment with this medicine. The use of effective contraception by both males and females during the treatment is important to avoid pregnancy.

Uses of Acalnib Capsule

Treatment of Blood cancer

Benefits of Acalnib Capsule

Treatment of Blood cancer
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Acalnib 100mg Capsule kills or stops the growth and prevents the multiplication of cancer cells. It is a potent and very toxic medicine, and one should discuss the risks and benefits with the doctor before taking this drug. Avoid drinking alcohol while taking this medicine and also inform the doctor if you have any persistent side effects.

Side effects of Acalnib Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Acalnib

Diarrhea
Upper respiratory tract infection
Headache
Decreased white blood cell count (neutrophils)
Musculoskeletal (bone, muscle or joint) pain
Lower respiratory tract infection
Fatigue

How to use Acalnib Capsule

Take this medicine in the dose and duration as advised by your doctor. Acalnib 100mg Capsule may be taken with or without food.

How Acalnib Capsule works

Acalnib 100mg Capsule works by blocking the action of an abnormal protein that promotes the multiplication of cancer cells. This helps stop the spread of cancer cells.

All substitutes for Acalnib 100mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Before taking Acalnib 100mg Capsule, tell your doctor about other medications (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
Avoid the use of antacids within 2 hours of taking this medicine.
You may be at risk of infection, so try to avoid crowds or people with colds, and immediately report fever or any other signs of infection to your doctor.
Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.
Drink plenty of water every 24 hours after the start of the treatment.
Eat foods that may help reduce diarrhea and take adequate rest.
Avoid contact sports or other situations where you may bruise or get injured since this medicine increases the risk of bleeding. Also, tell your doctor about any planned surgeries or dental procedures while taking Acalnib 100mg Capsule.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Acalnib 100mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Acalnib 100mg Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

UNSAFE

Acalnib 100mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Acalnib 100mg Capsule may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Acalnib 100mg Capsule in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Acalnib 100mg Capsule in patients with liver disease.

Interaction with drugs

Taking Acalnib with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Rifampicin (Injection Route)

Do not consume Acalabrutinib with Rifampicin. If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Rifampicin may reduce blood levels of Acalabrutinib.

Severe

Atazanavir (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Atazanavir may raise blood levels of Acalabrutinib.

Severe

Clarithromycin (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Clarithromycin may raise blood levels of Acalabrutinib.

Severe

Clarithromycin (Oral Route)

Concurrent use should be avoided. Please consult with your doctor. Clarithromycin may raise blood levels of Acalabrutinib.

Severe

Clarithromycin (Injection Route)

Concurrent use should be avoided. Please consult with your doctor. Clarithromycin may raise blood levels of Acalabrutinib.

Frequently asked questions

I am experiencing nausea and extreme tiredness. Is this due to Acalnib 100mg Capsule?

Nausea and fatigue or tiredness are some of the common side effects of Acalnib 100mg Capsule. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid salty, spicy, fried, or fatty food items. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.

How to get relief from diarrhea while on treatment with Acalnib 100mg Capsule?

Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soup and juice frequently to hydrate yourself.

Should I avoid any food and drinks while taking Acalnib 100mg Capsule?

You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent dehydration, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.

I have noticed some changes in my skin after taking Acalnib 100mg Capsule? What should I do?

Use a moisturizer to get relief from rashes and dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.

Why am I experiencing bleeding from my gums after brushing my teeth?

You may experience bleeding from gums due to a drop in the number of platelets (blood cells) in your blood. These blood cells help the blood clot when we bruise ourselves.

How to cope with tiredness and weakness after starting the treatment with Acalnib 100mg Capsule?

Various things can help you to reduce tiredness and cope with it, for example, gentle exercise. However, always consult your doctor before doing any kind of exercise. Q. Can Acalnib 100mg Capsule be taken with obinutuzumab?

What are some of the tests conducted before and during the treatment with Acalnib 100mg Capsule?

Your doctor will prescribe blood tests to check your levels of blood cells and how well your liver and kidneys are working.

Fact Box

Chemical Class

Phenylimidazoles

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Hetero Healthcare Limited
Address: S.no: 80-84, Melange towers, PatrikaNagar,Madhapur,Hyderabad. Telangana-500081.

Vendor Details

Country of origin: India

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Acalnib 100mg Capsule

Acalnib 100mg Capsule

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General Information

Contains

Marketer

Product introduction

Uses of Acalnib Capsule

Benefits of Acalnib Capsule

Side effects of Acalnib Capsule

How to use Acalnib Capsule

How Acalnib Capsule works

All substitutes for Acalnib 100mg Capsule

Acaone 100mg Capsule

Capbrusam Capsule 100mg

Calquence 100mg Capsule

Betatinib Capsule

Acabrunat Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Rifampicin (Injection Route)

Atazanavir (Oral Route)

Clarithromycin (Oral Route)

Clarithromycin (Oral Route)

Clarithromycin (Injection Route)

Frequently asked questions

I am experiencing nausea and extreme tiredness. Is this due to Acalnib 100mg Capsule?

How to get relief from diarrhea while on treatment with Acalnib 100mg Capsule?

Should I avoid any food and drinks while taking Acalnib 100mg Capsule?

I have noticed some changes in my skin after taking Acalnib 100mg Capsule? What should I do?

Why am I experiencing bleeding from my gums after brushing my teeth?

How to cope with tiredness and weakness after starting the treatment with Acalnib 100mg Capsule?

What are some of the tests conducted before and during the treatment with Acalnib 100mg Capsule?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests