Acalaside 100 Capsule is used to treat certain types of blood cancer such as mantle cell lymphoma, chronic lymphocytic leukemia, and small lymphocytic lymphoma. It works by blocking a protein that helps cancerous blood cells grow and survive, which helps slow the disease.
Acalaside 100 Capsule is taken orally, preferably with food or between meals. It should be used in the dose and duration prescribed by your doctor. It is advised to take this medicine at a fixed time and for as long as the doctor prescribes to avoid missing a dose. It may take several weeks or months for you to see or feel the benefits.
The most common side effects of Acalaside 100 Capsule include anemia, neutropenia, upper respiratory tract infection, thrombocytopenia, headache, diarrhea, and musculoskeletal pain. If these bother you or appear serious, let your doctor know as they might suggest ways of reducing or preventing these side effects.
Inform your doctor if you have a medical history of bleeding disorders, heart or liver disease, radiation treatment, or any infection. The risk of bleeding may increase if the patient is taking a blood thinner medicine along with Acalaside 100 Capsule. Many other medicines can affect or be affected by this medicine, so let your doctor know of all the medications you are using. Inform the doctor immediately if unusual bruising or bleeding or dark, tarry, or bloody stools and sore throat are noticed.
This medicine is known to reduce the number of blood cells in your blood, thereby increasing the susceptibility to infections. Regular blood tests are required to check the blood cell count along with the kidneys, liver, and heart functions during the treatment with this medicine. The use of effective contraception by both males and females during the treatment is important to avoid pregnancy.
Blood cancer, also called leukemia, is a cancer of the blood-forming tissues that decreases the body's ability to fight infection. Acalaside 100 Capsule kills or stops the growth and prevents the multiplication of cancer cells. It is a potent and very toxic medicine, and one should discuss the risks and benefits with the doctor before taking this drug. Avoid drinking alcohol while taking this medicine and also inform the doctor if you have any persistent side effects.
Side effects of Acalaside Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Acalaside
Anemia (low number of red blood cells)
Decreased white blood cell count (neutrophils)
Upper respiratory tract infection
Low blood platelets
Headache
Diarrhea
Musculoskeletal (bone, muscle or joint) pain
How to use Acalaside Capsule
Take this medicine in the dose and duration as advised by your doctor. Acalaside 100 Capsule may be taken with or without food.
How Acalaside Capsule works
Acalaside 100 Capsule works by blocking the action of an abnormal protein that promotes the multiplication of cancer cells. This helps stop the spread of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Acalaside 100 Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Acalaside 100 Capsule during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
CONSULT YOUR DOCTOR
Acalaside 100 Capsule may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
SAFE
Acalaside 100 Capsule does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Acalaside 100 Capsule is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver
SAFE IF PRESCRIBED
Acalaside 100 Capsule is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
What if you forget to take Acalaside Capsule?
If you miss a dose of Acalaside 100 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Before taking Acalaside 100 Capsule, tell your doctor about other medications (including prescription, over-the-counter, vitamins, herbal remedies, etc.).
Avoid the use of antacids within 2 hours of taking this medicine.
You may be at risk of infection, so try to avoid crowds or people with colds, and immediately report fever or any other signs of infection to your doctor.
Avoid sun exposure. Wear SPF 15 (or higher) sunblock and protective clothing.
Drink plenty of water every 24 hours after the start of the treatment.
Eat foods that may help reduce diarrhea and take adequate rest.
Avoid contact sports or other situations where you may bruise or get injured since this medicine increases the risk of bleeding. Also, tell your doctor about any planned surgeries or dental procedures while taking Acalaside 100 Capsule.
Fact Box
Chemical Class
Phenylimidazoles
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine Kinase Inhibitors (TKIs)
Interaction with drugs
Taking Acalaside with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks
I seem to have lung cancer , becoz all the symptoms are same as lung cancer. I test my blood, they suggests me that it is highly probable to lung cancer. Sir what can i do now. This is in preliminary stage
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
Do you think that lung cancer is diagnosed from blood
I am experiencing nausea and extreme tiredness. Is this due to Acalaside 100 Capsule?
Nausea and fatigue or tiredness are some of the common side effects of Acalaside 100 Capsule. Eat smaller, more frequent meals to reduce the feeling of nausea. Avoid salty, spicy, fried, or fatty food items. Take plenty of rest and do light exercise daily to keep yourself active and reduce fatigue.
How to get relief from diarrhea while on treatment with Acalaside 100 Capsule?
Food items with soluble fiber can help relieve diarrhea as they help absorb excess fluid from the body. These food items include bananas (ripe), oranges, boiled potatoes, white rice, curd, and oatmeal. Diarrhea can cause dehydration in the body, so drink 8-10 glasses of water to avoid dehydration. You can also have soup and juice frequently to hydrate yourself.
Should I avoid any food and drinks while taking Acalaside 100 Capsule?
You can continue with your normal diet unless your doctor tells you otherwise. However, it is advisable to sip water regularly to prevent dehydration, eat small, simple but nourishing snacks every few hours rather than large meals, and suck on hard candy or popsicles to prevent nausea and vomiting.
I have noticed some changes in my skin after taking Acalaside 100 Capsule? What should I do?
Use a moisturizer to get relief from rashes and dry and itchy skin. Avoid direct sunlight, wear protective clothing, and use sunscreen (SPF of more than 15) whenever you step outdoors. Do not go swimming if you have a rash because the chlorine in the water can make it worse. Avoid hot water baths and wear loose and cotton fabric clothes. Your skin will tend to become better once treatment is stopped.
Why am I experiencing bleeding from my gums after brushing my teeth?
You may experience bleeding from gums due to a drop in the number of platelets (blood cells) in your blood. These blood cells help the blood clot when we bruise ourselves.
How to cope with tiredness and weakness after starting the treatment with Acalaside 100 Capsule?
Various things can help you to reduce tiredness and cope with it, for example, gentle exercise. However, always consult your doctor before doing any kind of exercise. Q. Can Acalaside 100 Capsule be taken with obinutuzumab?
What are some of the tests conducted before and during the treatment with Acalaside 100 Capsule?
Your doctor will prescribe blood tests to check your levels of blood cells and how well your liver and kidneys are working.
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
1. Acalabrutinib [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2022. [Accessed 16 Nov. 2022] (online) Available from:
2. Acalabrutinib [Summary of Product Characteristics]. Södertälje, Sweden: AstraZeneca AB; 2020. [Accessed 16 Nov. 2022] (online) Available from:
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