Trofev 150mg Capsule
Prescription Required
Product introduction
Trofev 150mg Capsule is used in the treatment of idiopathic pulmonary fibrosis and non-small cell lung cancer. It works by targeting certain pathways involved in the growth and progression of these diseases and helps to stop or slow the spread of cancer cells.
Trofev 150mg Capsule should be taken with food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Diarrhea is a very common side effect of this medicine. You are advised to drink plenty of fluids and inform your doctor if it does not go away. Other common side effects include nausea, abdominal pain, vomiting, abnormal liver function tests, loss of appetite, headache, weight loss, and high blood pressure. Your doctor might ask you for some blood tests to monitor liver functioning.
Before taking it, tell your doctor if have a bleeding problem, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.
Uses of Trofev Capsule
Benefits of Trofev Capsule
In Treatment of Idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis is a lung disease caused by lung tissue becoming thick and stiff and eventually forming scar tissue within the lungs. The scarring, or fibrosis, seems to result from a cycle of damage and healing that occurs in the lungs. These changes are irreversible and the affected person may experience shortness of breath or dry cough as initial symptoms. Trofev 150mg Capsule kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.
In Treatment of Non-small cell lung cancer
Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Trofev 150mg Capsule helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.
Side effects of Trofev Capsule
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trofev
- Abdominal pain
- Diarrhea
- Nausea
- Vomiting
- Abnormal liver function tests
- Loss of appetite
- Headache
- Weight loss
- High blood pressure
How to use Trofev Capsule
Take this medicine in the dose and duration as advised by your doctor. Trofev 150mg Capsule is to be taken with food.
How Trofev Capsule works
Trofev 150mg Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. It also blocks pathways in the body that result in fibrosis, which is the thickening or scarring of the tissue. This helps to stop or slow the spread of cancer cells.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Trofev 150mg Capsule. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Trofev 150mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Trofev 150mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Trofev 150mg Capsule may cause side effects which could affect your ability to drive.
You may feel sick after taking this medicine and this could affect your driving.
You may feel sick after taking this medicine and this could affect your driving.
Kidney
CAUTION
Trofev 150mg Capsule should be used with caution in patients with severe kidney disease. Dose adjustment of Trofev 150mg Capsule may be needed. Please consult your doctor.
There is limited information available on the use of Trofev 150mg Capsule in these patients.
There is limited information available on the use of Trofev 150mg Capsule in these patients.
Liver
CAUTION
Trofev 150mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Trofev 150mg Capsule may be needed. Please consult your doctor.
Use of Trofev 150mg Capsule is not recommended in patients with moderate to severe liver disease.
Use of Trofev 150mg Capsule is not recommended in patients with moderate to severe liver disease.
What if you forget to take Trofev Capsule?
If you miss a dose of Trofev 150mg Capsule, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Trofev 150mg Capsule
₹83.7/Capsule
Fibronib 150 Capsule
Chemo Healthcare Pvt Ltd
₹83.7/capsule
same price
Bronchonib 150 Soft Gelatin Capsule
BDR Pharmaceuticals Internationals Pvt
₹72.9/capsule
13% cheaper
Macdanib 150mg Capsule
Macleods Pharmaceuticals Pvt Ltd
₹75.3/capsule
10% cheaper
Prutis 150mg Capsule
Hetero Drugs Ltd
₹83.7/capsule
same price
Mantedanib Capsule 150mg
Mankind Pharma Ltd
₹83.7/capsule
same price
Quick tips
- Take it with or without food, preferably at the same time each day.
- Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn't stop or if you find blood in your stools.
- Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
- Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
- It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
- Do not take this medicine if you are pregnant, planning to conceive or breastfeeding.
Fact Box
Chemical Class
Indolecarboxylic Acids
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Tyrosine Kinase Inhibitors (TKIs)
Interaction with drugs
Taking Trofev with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Nintedanib with Phenytoin. Phenytoin may reduce blood levels of Nintedanib.
Do not consume Nintedanib with Rifampicin. Rifampicin may reduce blood levels of Nintedanib.
Do not consume Nintedanib with Carbamazepine. Carbamazepine may reduce blood levels of Nintedanib.
Do not consume Nintedanib with Phenytoin. Phenytoin may reduce blood levels of Nintedanib.
Do not consume Nintedanib with Rifampicin. Rifampicin may reduce blood levels of Nintedanib.
Patient concerns
FAQs
What is Trofev 150mg Capsule used for?
Trofev 150mg Capsule is a medication that helps slow down scarring or stiffness in the lungs. It is mainly used to treat conditions like pulmonary fibrosis (lung scarring) and certain types of lung diseases. It works by blocking substances in your body that cause lung tissues to become thick and stiff. Trofev 150mg Capsule helps slow down lung function decline, but it is not a cure.
Can Trofev 150mg Capsule cause serious health problems?
Yes, though rare, Trofev 150mg Capsule may cause liver injury, heart attack, bleeding problems, kidney issues (protein in urine) and gastrointestinal perforation. Your doctor will monitor you regularly to reduce these risks.
Is Trofev 150mg Capsule safe for people with liver or kidney problems?
Trofev 150mg Capsule is not recommended for moderate or severe liver disease. In mild cases, the dose is usually reduced. Trofev 150mg Capsule should also be used with caution in kidney impairment, and monitoring is essential.
Who should avoid taking Trofev 150mg Capsule?
Trofev 150mg Capsule should be avoided in individuals if they are pregnant or planning pregnancy, have severe liver problems, have had recent stomach surgery or are at high risk of bleeding or blood clots. There are no official contraindications, but caution is advised in these specific groups.
What should I do if I get diarrhea while on Trofev 150mg Capsule?
Diarrhea is common during Trofev 150mg Capsule treatment. Your doctor may advise using anti-diarrheal medicine early. Drink fluids and contact your doctor if it is severe or long-lasting, as they may adjust your dose.
Can Trofev 150mg Capsule reverse lung damage?
No, Trofev 150mg Capsule does not reverse fibrosis (lung scarring), but it slows its progression, helping to preserve lung function and potentially improve quality of life over time.
What foods should I avoid while taking Trofev 150mg Capsule?
While there are not specific foods you should avoid, eating a light meal when taking Trofev 150mg Capsule can help reduce stomach upset. If you experience diarrhea, avoid spicy, fatty, or junk foods that might make it worse.
How long does it take for Trofev 150mg Capsule to work?
Trofev 150mg Capsule works gradually to slow down lung scarring. It is not a quick-relief medication, and it may take several weeks or months before you notice improvements. Your doctor will monitor your progress through regular check-ups and tests.
When should I contact my doctor while taking Trofev 150mg Capsule?
Contact your doctor immediately if you experience severe diarrhea that does not improve, unusual bleeding or bruising, severe stomach pain, yellowing of skin or eyes, dark urine and fever with infection symptoms.
Want to share the information?
Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Nintedanib. Ridgefield, Connecticut: Boehringer Ingelheim Pharmaceuticals, Inc.; 2014. [Accessed 26 Mar. 2019] (online) Available from:
- Nintedanib esilate. Bracknell, Berkshire: Boehringer Ingelheim Limited; 2015 [revised 31 Oct. 2018]. [Accessed 26 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Nintedanib. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Hetero Healthcare Limited
Address: S.no: 80-84, Melange towers, PatrikaNagar,Madhapur,Hyderabad. Telangana-500081.
Country of origin: India
Lab tests offered by us
Related/Popular tests
₹837
Inclusive of all taxes
MRP₹900 7% OFF
10.0 capsules in 1 strip
SOLD OUT