Pendex 40mg Injection
Product introduction
Pendex 40mg Injection is a medicine that reduces the amount of acid produced in your stomach. It is used for treating acid-related diseases of the stomach and intestine such as acid reflux, peptic ulcer disease, Zollinger-Ellison syndrome. It provides relief from symptoms and promotes healing.
Pendex 40mg Injection is also used to prevent stress ulcers in seriously ill patients and is administered before anesthetic medication to help prevent aspiration-related complications. It belongs to a class of medicines known as proton pump inhibitors (PPIs). This medicine is administered into a vein by a healthcare professional and will only be given to you if your doctor thinks that an injection is more suitable for you at the moment than a tablet. The dose will depend on your underlying condition and how you respond to the medicine. Your doctor will decide the duration of treatment but you should keep on taking it as prescribed, even if your symptoms disappear quickly. You can increase the efficiency of the treatment by eating smaller meals more often and avoiding caffeinated drinks (like tea and coffee), and spicy or fatty foods.
The most common side effects observed with this medicine include nausea, vomiting, headache, dizziness, flatulence, diarrhea, stomach pain, and thrombophlebitis (pain, redness, and swelling of the vein). These symptoms are generally mild but if they bother you or do not go away, consult your doctor. Long-term use of this medicine may lead to an increased risk of side effects. For instance, using this medicine for more than 1 year may increase your risk for bone fractures, especially with higher doses. Talk to your doctor about ways to prevent bone loss (osteoporosis), like taking calcium and vitamin D supplements.
Pendex 40mg Injection is not suitable for some people. Before taking this medicine, you need to tell your doctor if you have severe liver problems, are taking medicines for HIV, have ever had an allergic reaction to similar medicines in the past, or suffer from bone loss (osteoporosis). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid drinking alcohol as it makes your stomach produce excessive acid and can worsen your symptoms. Do not drive or use machinery or tools, if this medicine makes you feel dizzy or sleepy.
Uses of Pendex Injection
- Acidity
- Treatment of Heartburn
- Gastroesophageal reflux disease (Acid reflux)
- Peptic ulcer disease
- Treatment of Zollinger-Ellison syndrome
Benefits of Pendex Injection
In Treatment of Heartburn
Heartburn and acid reflux happens when a muscle above your stomach relaxes too much and allows stomach contents and acid to come back up into your esophagus and mouth. Pendex 40mg Injection belongs to a group of medicines called proton pump inhibitors. It reduces the amount of acid your stomach makes and relieves the pain associated with heartburn and acid reflux. You can increase the efficiency of the medicine by making certain lifestyle changes. These include avoiding foods that trigger the symptoms, eating smaller more frequent meals, losing weight if you are overweight.
In Treatment of Zollinger-Ellison syndrome
Zollinger-Ellison syndrome is a rare disorder where excessive stomach acid production leads to multiple peptic ulcers. Symptoms include abdominal pain, diarrhea, and heartburn. Pendex 40mg Injection By reducing the production of stomach acid, it helps alleviate symptoms such as abdominal pain, heartburn, and diarrhea. Esomeprazole also aids in the healing of peptic ulcers, which are common in this condition. By controlling the excessive acid secretion associated with Zollinger-Ellison syndrome, esomeprazole helps improve the overall digestive health and prevents complications such as gastrointestinal bleeding.
Side effects of Pendex Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Pendex
- Thrombophlebitis
- Dizziness
- Nausea
- Abdominal pain
- Flatulence
- Headache
- Vomiting
- Diarrhea
- Joint pain
- Injection site reaction
How to use Pendex Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Pendex Injection works
Pendex 40mg Injection is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which in turn relieves acid-related indigestion and heartburn.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Pendex 40mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Pendex 40mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Pendex 40mg Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
CONSULT YOUR DOCTOR
It is not known whether Pendex 40mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Kidney
SAFE IF PRESCRIBED
Pendex 40mg Injection is safe to use in patients with kidney disease. No dose adjustment of Pendex 40mg Injection is recommended.
Liver
CAUTION
Pendex 40mg Injection should be used with caution in patients with severe liver disease. Dose adjustment of Pendex 40mg Injection may be needed. Please consult your doctor.
What if you forget to take Pendex Injection?
If you miss a dose of Pendex 40mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Pendex 40mg Injection
₹47.5/Injection
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Quick tips
- It is given as an injection into the veins under the supervision of the doctor.
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Long-term use of Pendex 40mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
- Pendex 40mg Injection should be taken 1 hour before a meal, preferably in the morning.
- It is a well-tolerated medicine and provides relief for a long time.
- Some healthy tips to prevent acidity from happening:
- Avoid excessive intake of carbonated beverages/soft drinks, citrus juices, fried food, caffeinated beverages like tea and coffee.
- Avoid alcohol and smoking.
- Avoid eating late at night or before bedtime.
- Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.
- Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.
- Long-term use of Pendex 40mg Injection can cause weak bones and a deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.
- Consult your doctor right away if you develop decreased urination, edema (swelling due to fluid retention), lower back pain, nausea, fatigue, and rash or fever. These could be signs of a kidney problem.
Fact Box
Chemical Class
Sulfinylbenzimidazole Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Proton-Pump Inhibitors
Interaction with drugs
Taking Pendex with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Do not consume Erlotinib with Pantoprazole. Pantoprazole may reduce blood levels of Erlotinib.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Concurrent use may increase the risk of serious side effects of Methotrexate.
Patient concerns
FAQs
What is Pendex 40mg Injection used for?
Pendex 40mg Injection is used for the treatment of peptic ulcer disease, reflux esophagitis or gastroesophageal reflux disease (GERD). Pendex 40mg Injection prevents acidity associated with use of painkillers. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms.
How long does it take for Pendex 40mg Injection to work?
You should start to feel better within 2 to 3 days. It may take up to 4 weeks for Pendex 40mg Injection to work properly so you may still have some symptoms during this time.
Can I take Pendex 40mg Injection for a long term?
Pendex 40mg Injection is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Pendex 40mg Injection may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Pendex 40mg Injection as advised by your doctor and under their supervision.
Is a single dose of Pendex 40mg Injection sufficient?
No, a single dose may not be sufficient. However, with only a few doses of Pendex 40mg Injection you may get relief with the symptoms. Pendex 40mg Injection is usually needed only for a short term or upto 2 weeks for heartburn, indigestion, acid reflux. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Pendex 40mg Injection may be prescribed for a long term duration as well. Please consult your doctor if you do not feel better even after taking Pendex 40mg Injection regularly for 2 weeks as prescribed.
What are the long term side effects of Pendex 40mg Injection?
If Pendex 40mg Injection is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.
What is Pendex 40mg Injection used for?
Pendex 40mg Injection is used for the treatment of peptic ulcer disease, reflux esophagitis or gastroesophageal reflux disease (GERD). Pendex 40mg Injection prevents acidity associated with use of painkillers. It is also used to treat a disease associated with excessive acid production in the stomach known as Zollinger Ellison syndrome (ZES). It works by reducing the amount of acid made by your stomach and thus relieves your symptoms.
How long does it take for Pendex 40mg Injection to work?
You should start to feel better within 2 to 3 days. It may take up to 4 weeks for Pendex 40mg Injection to work properly so you may still have some symptoms during this time.
Is Pendex 40mg Injection safe?
Yes, Pendex 40mg Injection is relatively safe. Most of the people who take Pendex 40mg Injection do not get a side effect. It is advised to be taken as directed by the doctor for maximum benefits.
Can I take Pendex 40mg Injection for a long term?
Pendex 40mg Injection is usually prescribed for short term use only. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Pendex 40mg Injection may be prescribed for a long term duration as well. Long term use may carry an increased risk for side effects and must be discussed with the doctor. Please use Pendex 40mg Injection as advised by your doctor and under their supervision.
What are the long term side effects of Pendex 40mg Injection?
If Pendex 40mg Injection is used for more than 3 months, certain long term side effects may be seen. The most important of these is low magnesium levels in your blood which may make you feel tired, confused, dizzy, shaky or dizzy. You may also have muscle twitches or irregular heartbeat. If the use is further prolonged for more than a year, you may have an increased risk of bone fractures, stomach infections and vitamin B12 deficiency. Vitamin B12 deficiency can make you anemic, as a result of which you may feel more tired, weak, or pale. Additionally you may have palpitations, shortness of breath, lightheadedness, indigestion, loss of appetite, flatulence (gas) or nerve problems such as numbness, tingling and problem in walking.
What is the best time to take Pendex 40mg Injection?
Usually, Pendex 40mg Injection is taken once a day, first thing in the morning. If you take Pendex 40mg Injection twice a day, take 1 dose in the morning and 1 dose in the evening. The tablets should be swallowed whole (remember not be chewed or crushed) and taken at least 1 hour before a meal with some water.
Is a single dose of Pendex 40mg Injection sufficient?
No, a single dose may not be sufficient. However, with only a few doses of Pendex 40mg Injection you may get relief with the symptoms. Pendex 40mg Injection is usually needed only for a short term or upto 2 weeks for heartburn, indigestion, acid reflux. However, if need arises, such as for treating peptic ulcer disease and Zollinger Ellison syndrome (ZES), Pendex 40mg Injection may be prescribed for a long term duration as well. Please consult your doctor if you do not feel better even after taking Pendex 40mg Injection regularly for 2 weeks as prescribed.
Can I stop taking Pendex 40mg Injection if I feel better?
If you have been taking Pendex 40mg Injection for a long time, stopping it abruptly may lead to increased acid production, thereby worsening your symptoms. Therefore, you must discuss with your doctor about any dose changes or if you wish to come off Pendex 40mg Injection.
Does Pendex 40mg Injection cause weight gain?
Although rare but long-term treatment with Pendex 40mg Injection may cause weight gain. The reason could be the relief from reflux symptoms which could make you eat more. Consult your doctor for any weight-related concern.
Can I take alcohol with Pendex 40mg Injection?
No, alcohol intake is not advised with Pendex 40mg Injection. Alcohol itself does not affect the working of Pendex 40mg Injection, but it can increase the acid production. This may further cause worsening of your symptoms.
Can I take antacids along with Pendex 40mg Injection?
Yes, you can take antacids along with Pendex 40mg Injection. Take it 2 hours before or after you take Pendex 40mg Injection.
What dietary changes should I make to get relief from acidity?
Pendex 40mg Injection is best taken 1 hour before a meal. You should avoid spicy and fatty foods while taking this medicine. You must refrain from caffeinated drinks such as tea, coffee and cola. Alcohol intake should also be avoided as it may worsen your symptoms.
Are painkillers safe to take along with Pendex 40mg Injection?
Yes, it is safe to take painkillers along with Pendex 40mg Injection. Pendex 40mg Injection prevents acidity and stomach ulcers associated with the intake of painkillers. Pendex 40mg Injection is taken 1 hour before a meal. On the other hand, painkillers are usually taken with, or after a meal to avoid stomach upset.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Pantoprazole. Philadelphia, PA: Wyeth Laboratories; [Accessed on 28 Mar. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). Pantoprazole. [Accessed 28 Mar. 2019] (online) Available from:
- Pantoprazole [Product Information]. Sydney, Australia: Takeda Pharmaceuticals Australia Pty Ltd.; 2022. [Accessed 03 Aug. 2023] (online) Available from:
Marketer details
Name: Bharat Antibiotics Inc
Address: WP-482 IST FLOOR SHIV MARKET ASHOK VIHAR NEW DELHI-110052
Country of origin: India
Expires on or after: September, 2025
A licensed vendor partner from your nearest location will deliver Pendex 40mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: September, 2025
A licensed vendor partner from your nearest location will deliver Pendex 40mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: care@1mg.comPhone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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Question 1
What are you using this medicine for?
Acidity
Heartburn
Gastroesophageal reflux disease (Acid reflux)
Peptic ulcer disease
Zollinger-Ellison syndrome
Others