




Naxdom 500 Tablet
Product Summary :
Naxdom 500 Tablet is a combination of naproxen (an NSAID) and domperidone (an antiemetic). It is used to treat migraine headaches with associated nausea or vomiting. It works by reducing inflammation that causes pain and by controlling nausea, helping relieve migraine symptoms. Take it at the first sign of a migraine attack, preferably before meals, as advised by your doctor. Common side effects include dry mouth, dizziness, stomach pain, and tiredness. Avoid using it in patients with a history of stomach ulcers or bleeding. Use it with caution in patients with heart rhythm disorders or in those taking other medicines that may affect heart rhythm.Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 11 Apr 2026 | 05:00 PM (IST)



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Product introduction
Naxdom 500 Tablet may be prescribed alone or in combination with another medicine. It can be taken with or without food. The dose and duration will depend on the severity of your condition and how well it helps your symptoms. Use it regularly and do not discontinue it until the doctor tells you it is right to stop.
Using Naxdom 500 Tablet may cause common side effects such as headaches, ringing in the ears, dizziness, tiredness, rashes, and vision changes. If you experience such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
In general, you should try to use the smallest amount necessary to control your symptoms. Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using, so let your doctor know all the other medicines you are taking. Pregnant and breastfeeding women should consult their doctors first before using the medicine.
Uses of Naxdom Tablet
- Prevention of Migraine : Naxdom 500 Tablet helps prevent migraine, reducing symptoms like throbbing head pain, nausea, and sensitivity to light or sound.
Benefits of Naxdom Tablet
Migraine is a recurring condition that causes severe headaches along with nausea and vomiting. Naxdom 500 Tablet works by blocking chemicals responsible for pain sensation and signals that trigger nausea and vomiting during migraine attacks. This helps prevent migraine attacks, reduce their frequency, and relieve associated symptoms.
Side effects of Naxdom Tablet
- Dryness in mouth
- Ringing in ear
- Altered vision
- Tiredness
- Dizziness
- Drowsiness
- Rash
How to use Naxdom Tablet
How Naxdom Tablet works
Dosage
The dose of Naxdom 500 Tablet depends on the severity of your pain, the condition being treated, and your overall health. It is usually taken once or twice a day, as advised by your doctor. Your doctor will decide the right dose and duration of treatment for you.
Take Naxdom 500 Tablet exactly as prescribed, and do not exceed the recommended dose. Take it only for the duration recommended by your doctor. If your symptoms do not improve or worsen during treatment, consult your doctor.
Missed Dose
If you miss a dose of Naxdom 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Overdose
Overdose can cause lethargy, drowsiness, nausea, vomiting, agitation, altered consciousness, convulsions, disorientation, somnolence, and epigastric pain.
If overdose is suspected, please contact your doctor.
All substitutes for Naxdom 500 Tablet
Naprowel Forte 500mg/10mg Tablet
Napra D 500 Tablet
Minado 500 Tablet
Macprox DP 500 Tablet
Xenadom 500 Tablet
Quick tips
- Take Naxdom 500 Tablet exactly as prescribed. Do not take more than the recommended dose.
- Avoid alcohol while taking Naxdom 500 Tablet, as it may increase dizziness and the risk of stomach bleeding.
- Naxdom 500 Tablet may cause dizziness, so avoid driving or operating machinery until you know how it affects you.
- Do not take Naxdom 500 Tablet with other NSAID painkillers unless advised by your doctor.
- Inform your doctor if you have a history of stomach ulcers, acid reflux, heart disease, kidney disease, asthma, or high blood pressure.
- Stop taking Naxdom 500 Tablet and seek urgent medical help if you have black stools, vomit blood, severe stomach pain, chest pain, or swelling of the face or lips.
- Seek medical advice if you experience palpitations, fainting, or severe dizziness, as domperidone may affect heart rhythm in some people.
- Stay well hydrated and eat light meals if you experience nausea.
- Avoid common migraine triggers such as bright light, loud noise, missed meals, alcohol, and foods that can trigger your headaches.
- Consult your doctor if headaches become frequent or severe despite using Naxdom 500 Tablet.
Safety advice

Alcohol

Pregnancy

Breast feeding

Driving
Naxdom 500 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.

Kidney

Liver
Use of Naxdom 500 Tablet is not recommended in patients with moderate and severe liver disease.
Frequently asked questions
Fact Box
Habit Forming
Therapeutic Class
References
- Naproxen [Prescribing Information]. Nutley, New Jersey: Roche Laboratories Inc. [Accessed 22 Apr. 2019] (online) Available from:
- Leeford Healthcare: Naproxen and domperidone [Product Information]. [Accessed 20 Feb. 2025] (online) Available from:
- Domperidone and Naproxen [Product Information]. Ahmedabad, Gujarat: Torrent Pharmaceuticals Ltd.; 2024 [Accessed 20 Feb. 2025] (online) Available from:




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Marketer details
Address: Plot No. 314, 27/30, Sector-8A, IIE, SIDCUL, Ranipur, Haridwar-249 403, Uttarakhand
Vendor Details
A licensed vendor partner from your nearest location will deliver Naxdom 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
















