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Macprox DP 500 Tablet

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Product introduction

Macprox DP 500 Tablet is a combination of two medicines used in the prevention of migraines. It blocks the release of certain chemical messengers that cause pain, inflammation, and fever. It also blocks the signals in the brain that cause nausea and vomiting associated with migraines.

Macprox DP 500 Tablet may be prescribed alone or in combination with another medicine. It can be taken with or without food. The dose and duration will depend on the severity of your condition and how well it helps your symptoms. Use it regularly and do not discontinue using it until the doctor tells you it is alright to stop.

Using of the medicine may cause few common side effects such as flu-like symptoms, indigestion, and dryness in the mouth. If you experience any such side effects that do not go away or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms. In general, you should try to use the smallest amount necessary to control your symptoms.

Before using the medicine, you should tell your doctor if you have any other illnesses or disorders. It may also affect, or be affected by, some other medicines you are using so let your doctor know all the other medicines you are taking. It should be used with caution in patients who are alcoholics or have liver or kidney disease. Pregnant and breastfeeding women should consult their doctors first before using the medicine.

Uses of Macprox DP Tablet

Benefits of Macprox DP Tablet

In Prevention of Migraine

Macprox DP 500 Tablet blocks chemicals responsible for pain sensation and also blocks signals that cause nausea/vomiting associated with migraines. By preventing and reducing the frequency of migraine headaches, it can help you carry out your daily activities and have a better quality of life.

Side effects of Macprox DP Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macprox DP

  • Flu-like symptoms
  • Indigestion
  • Dryness in mouth

How to use Macprox DP Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Macprox DP 500 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Macprox DP Tablet works

Macprox DP 500 Tablet is a combination of two medicines: Naproxen and Domperidone. Naproxen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain due to migraine. Domperidone is a prokinetic which works on the region in the brain that controls vomiting associated with migraine. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Macprox DP 500 Tablet.
Pregnancy
CONSULT YOUR DOCTOR
Macprox DP 500 Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Macprox DP 500 Tablet is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Macprox DP 500 Tablet may cause side effects which could affect your ability to drive.
Macprox DP 500 Tablet may make you feel dizzy, depressed, sleepy, tired, or make it difficult to sleep. It may also affect your vision. This may affect your driving ability.
Kidney
CAUTION
Macprox DP 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Macprox DP 500 Tablet may be needed. Please consult your doctor.
Liver
CAUTION
Macprox DP 500 Tablet should be used with caution in patients with liver disease. Dose adjustment of Macprox DP 500 Tablet may be needed. Please consult your doctor.
Use of Macprox DP 500 Tablet is not recommended in patients with moderate and severe liver disease.

What if you forget to take Macprox DP Tablet?

If you miss a dose of Macprox DP 500 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Macprox DP 500 Tablet
₹8.8/Tablet
Minado 500 Tablet
Tas Med India Pvt Ltd
₹6.84/tablet
22% cheaper
Domstal NP 500mg/10mg Tablet
Torrent Pharmaceuticals Ltd
₹7.3/tablet
17% cheaper
Naprosyn D 500 Tablet
RPG Life Sciences Ltd
₹8.23/tablet
6% cheaper
Comig 500 Tablet
Seagull Pharmaceutical Pvt Ltd
₹8.47/tablet
4% cheaper
Dazmig D 500mg/10mg Tablet
Novalab Healthcare Pvt Ltd
₹9/tablet
2% costlier

Quick tips

  • You have been prescribed Macprox DP 500 Tablet for prevention of migraine headaches.
  • Do not take it to treat an acute attack of migraine.
  • Some tips that may help avoid a migraine attack:
    • Have your meals at the same time everyday
    • Avoid bright lights and extreme temperatures
    • Avoid loud music and noisy places
    • Avoid chocolates,  cheese, processed food, alcohol and smoking
    • Get enough sleep and avoid stress
  • It may cause sleepiness. Do not drive or do anything that requires mental focus until you know how Macprox DP 500 Tablet affects you.
  • Avoid consuming alcohol as it may cause new and worse headaches.
  • Keep taking it every day, as prescribed by your doctor, even if you do not have any symptoms.

Fact Box

Habit Forming
No
Therapeutic Class
PAIN ANALGESICS

Patient concerns

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I am facing issue of headache from last 3-4 years.i have consulted allopathy and they have given me sibelum 10 for migrane and asked to take metopar(paracetamol) when ever pain is too much.i am nit taking sibelum now but i am taking metopar when ever required.so i want a homeopathy consultatation if it can be cured by homeopathy or the level of headache can be lowered. Currently i face headache once in a week and i had to take metopar. Kindly suggest. My weight 80 kg And i am taking some neuro medicines ( stalopam 10, amitone 10) I also have cholesterol and taking (atorec 20)
Dr. Faran Siddiqui
Homeopathy
Migraine and headache are two different things migraine is primarily headache of one side in symmetrically
Some time at a sudden Strong half headache pain in left side and also left eye tearing Please consult me
Dr. Pushkar Mani
Physician
it could be migraine
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User feedback


FAQs

Q. What is Macprox DP 500 Tablet?

Macprox DP 500 Tablet is a combination of two medicines: Naproxen and Domperidone. This combination helps in relieving the symptoms of migraine like headache, nausea and vomiting. Naproxen is a pain-killer that blocks the release of certain chemical messengers that cause headache. Domperidone is an anti-emetic agent (prokinetic). It increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This helps in relieving vomiting.

Q. Can I stop taking Macprox DP 500 Tablet when my migraine symptoms are relieved?

No, do not stop taking Macprox DP 500 Tablet until advised by your doctor.

Q. Can the use of Macprox DP 500 Tablet cause diarrhea?

Yes, the use of Macprox DP 500 Tablet can cause diarrhea. In case, you experience diarrhea, drink plenty of water or other fluids. Talk to your doctor if diarrhea persists and you notice any signs of dehydration, like less urination with dark coloured and strong-smelling urine. Do not take any other medicine without consulting a doctor.

Q. Are there any specific contraindications associated with the use of Macprox DP 500 Tablet?

The use of Macprox DP 500 Tablet is considered to be harmful for patients with known allergy to any of the components or excipients of this medicine or in patients with known allergy to other painkillers (NSAIDs). The use of this medicine should preferably be avoided in patients with a history of stomach ulcers or in patients with active, recurrent stomach ulcer/bleeding. It should also be avoided in patients with history of heart failure, high blood pressure, and liver or kidney disease.

Q. Can the use of Macprox DP 500 Tablet cause damage to kidneys?

Yes, the long-term use of Macprox DP 500 Tablet can cause damage to the kidneys. Normal kidneys produce a chemical called prostaglandins that protects them from damage. Use of painkillers lower the levels of prostaglandins in the body, which leads to kidney damage on long-term use. Use of painkillers is not recommended to patients with underlying kidney disease.

Q. Can I take a higher than the recommended dose of Macprox DP 500 Tablet?

No, taking a higher than the recommended dose of Macprox DP 500 Tablet can increase the risks of side effects. If you are experiencing increased severity of migraine attacks which are not relieved by the recommended doses, please consult your doctor for re-evaluation.

Q. What are the recommended storage conditions for Macprox DP 500 Tablet?

Keep this medicine in the container or the pack it came in, tightly closed. Store it as mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Naproxen. Nutley, New Jersey: Roche Laboratories Inc. [Accessed 22 Apr. 2019] (online) Available from:External Link
  2. Domperidone and domperidone maleate. South Ruislip, Middlesex: Aurobindo Pharma - Milpharm Ltd.; 2003 [revised 14 Nov. 2017]. [Accessed 24 Jan. 2019] (online) Available from:External Link
  3. Drugs.com. Naproxen. [Accessed 22 Apr. 2019] (online) Available from:External Link
  4. Drugs.com. Domperidone. [Accessed 22 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer address

Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.
Country of origin: India
Expires on or after: December, 2022

A licensed vendor partner from your nearest location will deliver Macprox DP 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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