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Naprowel 500 Tablet

Naproxen (500mg)
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Naprowel 500 Tablet is a pain-relieving medicine. It provides relief from pain and inflammation in conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, gout, and juvenile arthritis. It also helps in relieving muscle and joint pain, headache, toothache, and menstrual cramps.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 28 Apr 2026 | 05:56 PM (IST)
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General Information

The content is shown in English
Naprowel 500 Tablet image
Naprowel 500 Tablet image
Naprowel 500 Tablet image

Product introduction

Naprowel 500 Tablet should be taken with food to avoid stomach upset and reduce side effects. In general, you should try to use the smallest amount necessary to control your symptoms, for the shortest possible time. You should take this medicine regularly while you need it. Try not to miss doses as it will become less effective if you do.

The most common side effects of this medicine include indigestion, abdominal pain, nausea, headache, rash, bruises, and edema. If any of these side effects do not resolve with time or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Naprowel 500 Tablet should be used with caution in patients with liver, kidney, or heart problems, as it may worsen these conditions. Avoid use in severe heart failure and advanced kidney disease unless advised by a doctor. Monitor blood pressure, as it may reduce the effect of some antihypertensive medicines. Discontinue use if symptoms like rash, breathing difficulty, or signs of liver issues occur. It should not be used in patients with aspirin-sensitive asthma.

Uses of Naprowel Tablet

Benefits of Naprowel Tablet

Pain relief
Naprowel 500 Tablet is used for short-term relief of pain, inflammation, and swelling in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Naprowel Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Naprowel
  • Ecchymosis (discoloration of the skin resulting from bleeding underneath)
  • Skin eruptions
  • Itching
  • Shortness of breath
  • Gastrointestinal ulcer
  • Edema (swelling)
  • Abdominal pain
  • Heartburn
  • Vomiting
  • Headache
  • Dizziness
  • Nausea
  • Flatulence
  • Constipation
  • Drowsiness
  • Ringing in ear

How to use Naprowel Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Naprowel 500 Tablet may be taken with or without food.

How Naprowel Tablet works

Naprowel 500 Tablet is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain and inflammation (redness and swelling).

All substitutes for Naprowel 500 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • You have been prescribed Naprowel 500 Tablet to relieve pain and inflammation.
  • Take it with food or milk to prevent upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
  • Do not take indigestion remedies (antacids) within two hours of taking Naprowel 500 Tablet.
  • Avoid consuming alcohol while taking Naprowel 500 Tablet as it can increase your risk of stomach problems.
  • Inform your doctor if you have a history of heart disease or stroke.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Naprowel 500 Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Naprowel 500 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CAUTION
Naprowel 500 Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Naprowel 500 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Naprowel 500 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, it should not be used in case of severe renal disease.
Liver

Liver

CAUTION
Naprowel 500 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Naprowel with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Tacrolimus (Oral Route)

If concurrent use is essential, your doctor may monitor your tacrolimus levels, potassium levels and kidney function closely. They may adjust the doses as per the observations.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.
Severe

Methotrexate (Injection Route)

Please consult with your doctor. Doctor may monitor liver function and blood cell counts.

Frequently asked questions

Naprowel 500 Tablet is a pain killer and is used to reduce pain. It belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs) and is used to treat diseases of joints such as rheumatoid arthritis (including in children), osteoarthritis, ankylosing spondylitis. It is also used to treat attacks of gout, muscle and bone disorders and painful periods.
Naprowel 500 Tablet is not recommended for the treatment of flu. Talk to your doctor if you have the flu before taking any medicines.
Naprowel 500 Tablet is not an over the counter (OTC) product. It belongs to a class of prescription drugs.

Fact Box

Chemical Class

Naphthalene derivative

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

Action Class

NSAID's- Non-Selective COX 1&2 Inhibitors (propionic acid)

References

  1. Furst DE, Ulrich RW, Varkey-Altamirano C. Nonsteroidal Anti-Inflammatory Drugs, Disease Modifying Antirheumatic Drugs, Nonopioids Analgesics, & Drugs Used in Gout. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 628.
  2. Grosser T, Smyth E, FitzGerald GA. Anti-Inflammatory, Antipyretic, and Analgesic Agents; Pharmacotherapy of Gout. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 988-89.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 955-58.
  4. Naproxen. Nutley, New Jersey: Roche Laboratories Inc. [Accessed 02 Apr. 2019] (online) Available from:
  5. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Jornal de Pediatria. 2004; 80(5): 4-6. [Accessed 02 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:
  7. Naproxen. Mahwah, NJ. Glenmark Pharmaceuticals Inc.; 2024 [Accessed 19 Jan. 2026] (online). Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Leeford Healthcare Ltd
Address: 203, Mangalam, Kulupwadi, Borivali (E), Mumbai-400066

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Naprowel 500 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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