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DAPamac Trio 10mg/500mg/100mg Tablet is a combination medicine that helps control blood sugar levels. This medicine is used with diet and exercise to improve blood sugar control in adults with type 2 diabetes mellitus. It helps in the proper utilization of insulin, thereby lowering the blood sugar level.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 13 Mar 2026 | 01:39 PM (IST)
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General Information

Contains

Dapagliflozin (10mg)+ Metformin (500mg)+ Sitagliptin (100mg)

Marketer

Macleods Pharmaceuticals Pvt Ltd

Storage

Store below 30°C
The content is shown in English
DAPamac Trio 10mg/500mg/100mg Tablet image
DAPamac Trio 10mg/500mg/100mg Tablet image
DAPamac Trio 10mg/500mg/100mg Tablet image
DAPamac Trio 10mg/500mg/100mg Tablet image

Product introduction

DAPamac Trio 10mg/500mg/100mg Tablet can be taken with or without food at any time of the day, but try to take it at the same time every day. The dose will be decided by your doctor, so do not stop taking it without asking them. If you do, your blood sugar levels may increase your risk of serious complications like kidney damage and blindness. This medicine is only a part of the treatment program that should include a healthy diet, regular exercise, and weight reduction as advised by your doctor.


The most common side effects of this medicine include urinary tract infection, nasal congestion, sore throat, and upper respiratory tract infection. Drinking plenty of fluids while using it will help prevent dehydration. Some people may develop fungal infections in the genital area. Maintaining good hygiene can help prevent this.


Before taking DAPamac Trio 10mg/500mg/100mg Tablet, inform your doctor if you have any kidney or liver problems, a urinary tract infection, or if you are on water pills (diuretics). Pregnant or breastfeeding women should also consult their doctor before taking it. Avoid excessive alcohol intake while taking this medicine, as this may increase the risk of some side effects. Monitor your blood sugar levels regularly while taking this medicine.

Uses of DAPamac Tablet

Benefits of DAPamac Tablet

Treatment of Type 2 diabetes mellitus
DAPamac Trio 10mg/500mg/100mg Tablet is a medicine that helps control high blood glucose (sugar) levels. It helps get rid of extra glucose from the body through urine. Lowering blood glucose levels is an essential part of managing diabetes, as this reduces the risk of serious complications, such as kidney damage, eye damage, nerve problems, and loss of limbs. This medicine will reduce the risk of death from cardiovascular disease if you have type 2 diabetes and cardiovascular disease. Taking DAPamac Trio 10mg/500mg/100mg Tablet regularly with proper diet and exercise will help you live a normal, healthy life. You should keep using it for as long as it is prescribed for a healthy future.

Side effects of DAPamac Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of DAPamac
  • Diarrhea
  • Nausea
  • Vomiting
  • Flatulence
  • Genital fungal infection
  • Nasopharyngitis (inflammation of the throat and nasal passages)
  • Urinary tract infection
  • Headache

How to use DAPamac Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DAPamac Trio 10mg/500mg/100mg Tablet may be taken with or without food.

How DAPamac Tablet works

DAPamac Trio 10mg/500mg/100mg Tablet is a combination of three antidiabetic medicines. Dapagliflozin increases urinary glucose excretion and reduces blood glucose levels. Metformin decreases the amount of glucose you absorb from your food and the amount of glucose made by the liver. Metformin also increases the body's response to insulin, a natural substance that controls the amount of glucose in the blood. Sitagliptin helps control blood sugar levels by increasing substances (incretins) in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when there is too much sugar in the blood.

All substitutes for DAPamac Trio 10mg/500mg/100mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Gluxit Trio 10mg/500mg/100mg Tablet

by Eris Lifesciences Ltd
₹20.93/tablet
29% costlier
<h3 class=bodySemiBold>Gluxit Trio 10mg/500mg/100mg Tablet</h3>

Sgltd-Trio 10mg/500mg/100mg Tablet

by Mankind Pharma Ltd
₹18.9/tablet
17% costlier
<h3 class=bodySemiBold>Sgltd-Trio 10mg/500mg/100mg Tablet</h3>

Lupisit DM 10mg/500mg/100mg Tablet

by Lupin Ltd
₹23.9/tablet
48% costlier
<h3 class=bodySemiBold>Lupisit DM 10mg/500mg/100mg Tablet</h3>

Sitara DM 10mg/500mg/100mg Tablet

by Intas Pharmaceuticals Ltd
₹21.8/tablet
35% costlier
<h3 class=bodySemiBold>Sitara DM 10mg/500mg/100mg Tablet</h3>

Glucreta SM 10mg/500mg/100mg Tablet

by Torrent Pharmaceuticals Ltd
₹24.74/tablet
53% costlier
<h3 class=bodySemiBold>Glucreta SM 10mg/500mg/100mg Tablet</h3>

Quick tips

  • Your doctor will monitor your blood sugar levels and kidney function regularly while you are taking this medication.
  • Hypoglycemia (low blood sugar level) may occur when DAPamac Trio 10mg/500mg/100mg Tablet is taken along with other antidiabetic medicines, alcohol, or when delaying/skipping a meal. Check your blood sugar levels and have a snack/sugar source for immediate relief.
  • If you get unusually thirsty, pass urine more frequently, or feel tired, let your doctor know. These are signs that there is too much sugar in your blood, and your dose may need adjusting.
  • Lifestyle changes, like a low-fat and salt diet, exercise, not smoking, and cutting down on the amount of alcohol you normally drink, may help this medicine work better.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with DAPamac Trio 10mg/500mg/100mg Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of DAPamac Trio 10mg/500mg/100mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
DAPamac Trio 10mg/500mg/100mg Tablet should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

CAUTION
DAPamac Trio 10mg/500mg/100mg Tablet may affect your driving ability if your blood sugar becomes too low or too high. Monitor your blood glucose and avoid driving if affected.
Kidney

Kidney

CAUTION
DAPamac Trio 10mg/500mg/100mg Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
DAPamac Trio 10mg/500mg/100mg Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

DAPamac Trio 10mg/500mg/100mg Tablet helps lower blood sugar levels in adults with type 2 diabetes. It combines three drugs that work in different ways to improve blood sugar control and may also help with weight loss and protect the heart and kidneys in some people.
No. DAPamac Trio 10mg/500mg/100mg Tablet is only for adults with type 2 diabetes. It should not be used in people with type 1 diabetes, or those who have severe kidney problems, metabolic acidosis, or diabetic ketoacidosis (DKA)—a serious condition caused by very high blood sugar.
During DAPamac Trio 10mg/500mg/100mg Tablet treatment, contact a doctor if serious side effects appear. These may include signs of lactic acidosis (such as weakness, breathing difficulty, or stomach pain), symptoms of ketoacidosis (like nausea, vomiting, confusion, or fruity breath), painful or persistent genital or urinary infections, signs of pancreatitis (severe stomach pain or nausea), or allergic reactions (rash, swelling, or breathing problems). These effects are rare but require prompt medical attention.
Yes, people with kidney or liver problems need to be monitored closely or may need a different medication. Your doctor will do regular blood tests to check your kidney and liver function during DAPamac Trio 10mg/500mg/100mg Tablet treatment.
DAPamac Trio 10mg/500mg/100mg Tablet is not recommended during pregnancy or breastfeeding. Some of the ingredients may harm the baby or affect milk production. Let your doctor know if you're planning a pregnancy.
DAPamac Trio 10mg/500mg/100mg Tablet does not usually cause low blood sugar on its own, but it can happen if you take it with insulin or certain diabetes pills. Always carry something sweet (like glucose tablets or candy) in case of symptoms like shakiness, sweating, or dizziness.
During DAPamac Trio 10mg/500mg/100mg Tablet treatment, you should avoid drinking alcohol heavily as it increases the risk of lactic acidosis. Also, be cautious with dehydration and drink enough fluids, especially in hot weather or when you're sick.
Some medicines, including diuretics (water pills), blood pressure drugs, and steroids, may interact with DAPamac Trio 10mg/500mg/100mg Tablet. Always tell your doctor or pharmacist about all other medicines or supplements you’re using.

Fact Box

Habit Forming

No

Therapeutic Class

ANTI DIABETIC

Related lab tests

Glucose - Fasting Blood

Glucose - Postprandial Blood

Glycosylated Hemoglobin

References

  1. Dapagliflozin [Prescribing Information]. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2020. [Accessed 14 Aug. 2024] (online) Available from:
  2. Sitagliptin/metformin HCL [Prescribing Information]. Darmstadt, Germany: Merck Sharp & Dohme Corp.; 2012. [Accessed 14 Aug. 2024] (online) Available from:
  3. Dapagliflozin+Metformin+Sitagliptin [Prescribing Information]. Telangana, India: MSN Laboratories Private Limited; 2022. [Accessed 30 Mar. 2025] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Macleods Pharmaceuticals Pvt Ltd
Address: Atlanta Arcade, Marol Church Road, Andheri (East), Mumbai - 400059, INDIA.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver DAPamac Trio 10mg/500mg/100mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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