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9 PM Eye Drop is a medicine used to reduce pressure in the eyes in people with glaucoma and ocular hypertension (high pressure in the eye). If the pressure in your eye is too high it can damage your sight, potentially leading to blindness. It works by helping fluid flow from inside the eye into the blood.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 29 Apr 2026 | 01:01 PM (IST)
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General Information

Contains

Latanoprost (0.005% w/v)

Marketer

Cipla Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
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Product introduction

9 PM Eye Drop is suitable for adults and children and can be used by itself or in combination with other eye medicines to reduce pressure. Follow the instructions given by your doctor and use this medicine regularly to get the most benefit. If you stop using it, pressure in the eye could increase and damage your sight. Never use a bottle if the seal is broken before you use it for the first time. If you wear contact lenses, make sure you remove them before instilling and wait for at least 15 minutes before putting them back. 

The most common side effects include eyelashes changes, eye pain and sensitivity to light. It may also cause blurred vision, dryness in the eye, a gradual change in color of the eye, and other rare effects. If you get any side effects, talk to your doctor. Your doctor may be able to tell you ways of reducing or preventing some side effects or suggest another treatment. If your vision is blurred or you have other changes in sight for a time, do not drive until your vision is clear. This is usually a short-term side effect. Do not use this medicine if you are pregnant or trying to become pregnant, or if you are breastfeeding.

Uses of 9 PM Eye Drop

Benefits of 9 PM Eye Drop

Glaucoma
9 PM Eye Drop is a medicine used to reduce pressure in your eyes (ocular hypertension). This pressure can lead to an illness called glaucoma. If the pressure in your eye is too high, it can damage your sight. This medicine works by helping the fluid to flow from inside the eye into your bloodstream. It may be used alone or with other eye drops. Do not use it too often as that can make it less effective. You should only use it in the affected eye and take it regularly as prescribed by your doctor. If you stop taking it, the pressure in your eye will not be controlled. This could lead to a loss of sight.
Ocular hypertension
9 PM Eye Drop belongs to a group of medicines called prostaglandin analogue. It is used to reduce pressure in your eyes. It increases the flow of fluid from inside the eye into the bloodstream thereby lowering the increased eye pressure. If the pressure in your eye is too high, it can damage your sight. You should only use it in the affected eye and take it regularly as prescribed by your doctor. If you stop taking it, the pressure in your eye will not be controlled.

Side effects of 9 PM Eye Drop

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of 9 PM
  • Foreign body sensation
  • Itching
  • Stinging in the eyes
  • Eyelash changes
  • Eye pain
  • Increased sensitivity to light
  • Burning sensation in eye
  • Eye itching
  • Conjunctival hyperemia

How to use 9 PM Eye Drop

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Hold the dropper close to the eye without touching it. Gently squeeze the dropper and place the medicine inside the lower eyelid. Wipe off the extra liquid.

How 9 PM Eye Drop works

9 PM Eye Drop is a prostaglandin analogue. It works by increasing the outflow of aqueous humor, thereby lowering the increased eye pressure.

Quick tips

  • 9 PM Eye Drop helps lower high pressure in the eye and reduces the risk of vision loss.
  • For best results, put one drop once a day in the evening/night in the affected eye(s).
  • Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
  • Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
  • 9 PM Eye Drop may cause brown pigmentation of the iris. This discoloration may be permanent.
  • Your eyelashes may become more dense and eyelid skin may darken. These changes should disappear after discontinuing 9 PM Eye Drop.
  • 9 PM Eye Drop helps lower high pressure in the eye and reduces the risk of vision loss.
  • For best results, put one drop once a day in the evening/night in the affected eye(s).
  • Apply pressure on the corner of the eye (close to the nose) for about 1 minute, immediately after instilling the drop.
  • 9 PM Eye Drop may cause brown pigmentation of the iris. This discoloration may be permanent.
  • Your eyelashes may become more dense and eyelid skin may darken. These changes should disappear after discontinuing 9 PM Eye Drop.
  • Wait for at least 5-10 minutes before delivering the next medication in the same eye to avoid dilution.
  • Make sure to use within 4 weeks of opening the bottle.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of 9 PM Eye Drop during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of 9 PM Eye Drop during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
9 PM Eye Drop may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Interaction with drugs

Taking 9 PM with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Bimatoprost (Eye Route)

Do not use Latanoprost with Bimatoprost. If concurrent use is essential, your doctor may monitor the fluid pressure inside the eye.
Moderate

Travoprost (Eye Route)

Do not consume Latanoprost with Travoprost. If concurrent use is essential, your doctor may monitor your intraocular pressure closely.
Mild

Diclofenac (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Diclofenac may alter the efficacy of Latanoprost.
Mild

Diclofenac (Transdermal Route)

Talk to your doctor if you notice any unusual symptoms. Diclofenac may alter the efficacy of Latanoprost.
Mild

Diclofenac (Injection Route)

Talk to your doctor if you notice any unusual symptoms. Diclofenac may alter the efficacy of Latanoprost.

Frequently asked questions

Yes, you can use contact lenses while using 9 PM Eye Drop. However, remove your contact lenses before instilling 9 PM Eye Drop. You can re-insert the lenses 15 minutes after instilling 9 PM Eye Drop. Contact your doctor if eye irritation occurs and persists.
Yes, continued use of 9 PM Eye Drop may cause a change in the color of the iris, particularly brown pigmentation. This color change is more common in people who have mixed color eyes (blue-brown, grey-brown, yellow-brown or green-brown). The change may be more noticeable if it is used in only one eye. This change in color is likely to be permanent. Additionally, the eyelashes may also become denser and the color of the eyelids may darken. However, this is usually temporary and reverts to normal once the use of 9 PM Eye Drop is discontinued.
If you have to use other eye drops, wait for at least 5 minutes before using them. You should inform your doctor about any other medicine which you are using since it may interfere with the working of 9 PM Eye Drop.
After using the eye drops you should close your eyes for at least 2-3 minutes so that the medicine does not run off and gets absorbed in the eye.
Yes, the unopened bottle needs to be refrigerated at 2° to 8°C (36° to 46°F). However, once the bottle is opened for use, it may be stored at room temperature up to 25°C (77°F) for not longer than 6 weeks.
The pressure in the eyes starts decreasing after about 3-4 hours of using 9 PM Eye Drop and the maximum effect is reached after 8-12 hours.
It is recommended to use 9 PM Eye Drop in the evening for best results. 9 PM Eye Drop, when used in the evening for the first few days, showed significantly effective results in lowering the eye pressure. The effect of this medicine remains for about 24 hours after administration.
You should contact your doctor immediately if you develop an eye infection, injury, conjunctivitis, or an eyelid reaction. Along with that, the doctor should be informed if you have undergone any eye surgery earlier. Use 9 PM Eye Drop as prescribed by the doctor.

Fact Box

Chemical Class

Prostaglandin derivative

Habit Forming

No

Therapeutic Class

OPHTHAL

Action Class

Prostaglandin F2α (PGF2α) Analogues

References

  1. Smyth EM, Grosser T, FitzGerald GA. Lipid-Derived Autacoids: Eicosanoids and Platelet-Activating Factor. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 952.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 781.
  3. Smyth EM, FitzGerald GA. The Eicosanoids: Prostaglandins, Tromboxanes, Leukotriens, & Related Compounds. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 328.
  4. Latanoprost. Romford, Essex: Martindale Pharma; 2010 [revised 22 Jan. 2019]. [Accessed 04 Apr. 2019] (online) Available from:
  5. Latanoprost. Puurs, Belgium: Pfizer Manufacturing; 1996 [revised Jun. 2014]. [Accessed 04 Apr. 2019] (online) Available from:
  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
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User feedback

Once A Day
100%
Glaucoma
96%
Others
4%
Average
52%
Excellent
43%
Poor
6%
Foreign body sensation in eyes
25%
Stinging in the eyes
25%
Foreign body sensation
12%
Burning sensation in eye
12%
Eye itching
12%
With or without food
75%
With food
25%
Expensive
64%
Average
28%
Not Expensive
8%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver 9 PM Eye Drop. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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