How can we help?

Home

Total Leukocyte Count

Also referred as

White blood cell count

Leucocyte

TLC

WBC Count

Total counts

523+ booked recently

For men & women

Earliest reports in

48 hours

Contains

1 test

Know more about this test

The Total Leukocyte Count, also known as TLC test measures the number of leukocytes, also known as white blood cells (WBCs), in the blood. This test helps detect infection, inflammation, and bone marrow disorders. It is often done as part of a complete blood count test that also measures other types of blood cells.

Samples required

Blood

Find out

Why is this test booked?

Preparations

No special preparation is required.

Sample Collection

Who will collect your samples?

Understanding Total Leukocyte Count

Leukocytes or WBCs are white-colored blood cells that are a part of the immune system and defend the body against infections and diseases. There are five types of WBCs, namely basophils, eosinophils, lymphocytes, monocytes, and neutrophils, and each one supports the immune system differently.

A decrease in the TLC count is referred to as leukopenia and indicates a decline in the body’s ability to fight infections. Whereas, an increase in TLC, known as leukocytosis, indicates acute infections and inflammation. Your doctor may advise the Total Leukocyte Count test if you show symptoms suggestive of an infection, inflammation, or other health conditions like bone marrow disorders. However, this test is followed up with other tests to determine the exact cause of the abnormal results. A TLC test is also used to monitor your response to medical treatments that can affect the immune system, including chemotherapy which is known to affect the number of leukocytes. No special preparation is needed for a TLC test; eat or drink normally as per your daily routine.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. The test results will help your doctor determine your medical condition, make recommendations for lifestyle modifications such as diet and exercise, decide whether or not medication will be required to manage your condition and formulate your overall treatment plan.

What does Total Leukocyte Count measure?

The Total Leukocyte Count test measures the numbers of all types of leukocytes, namely neutrophil, lymphocyte, monocyte, eosinophil, and basophil, in your blood. Leukocytes or WBCs are an essential part of our immune system. These cells are produced in the bone marrow and defend the body against infections and diseases. Each type of WBC plays a unique role to protect against infections and is present in different numbers.

Frequently booked together

FAQs related to Total Leukocyte Count

What is Leukocytosis?

Leukocytosis is a condition where the leukocyte count is higher than its normal range. This may occur due to infections; inflammation; or conditions, such as rheumatoid arthritis, allergies, cancers like leukemia, myeloproliferative neoplasms, or conditions causing necrosis (tissue death) like severe burns, trauma, surgery, etc. Other factors like cigarette smoking, surgical spleen removal, allergies, heavy physical exercise, pregnancy, or certain medicines like corticosteroids, epinephrine, heparin, lithium, etc., can also cause leukocytosis.

What is leukopenia?

Leukopenia is a condition where the leukocyte count is lower than its normal range. This may occur due to bone marrow damage or disorders, radiotherapy or chemotherapy, blood cancers, or certain infections like human immunodeficiency virus (HIV).

In what conditions a doctor may suggest the TLC test?

Your doctor may suggest the TLC test for a wide range of health conditions such as infections, inflammation, and blood cancer, or if you are on certain immunosuppressive medications or treatments.

Is there any risk associated with this test?

There is usually no risk associated with this test. However, some people may feel a slight sting while the needle is pricked and may experience some bleeding that is normal and usually not bothersome. Rarely some people may experience slight swelling or bruising at the site of the needle prick. Applying ice 3-4 times a day for about a week may help reduce swelling and bruising. If it does not get better, consult your doctor.

Content created by

Dr. Swati Gupta (Anand)

MD Lab Medicine, MBBS

Want to know moreRead our editorial policy

Last Updated

18th Oct 2025