TORCH Profile 8 Parameters
Understanding TORCH Profile 8 Parameters
What is TORCH Profile 8 Parameters?
TORCH Profile 8 is a panel of 8 tests that screens for infectious diseases including Toxoplasmosis, Rubella, Herpes and Cytomegalovirus infection. These tests detect the presence of IgM and IgG antibodies produced by the body in response to these infections.
The test can also be performed to screen pregnant women for infections that can cause congenital defects in newborns. Pregnant women often get this test at their first prenatal visit to find these infections early in pregnancy. This helps in initiating treatment at the right time.
What does TORCH Profile 8 Parameters measure?Contains 8 tests
Toxoplasma gondii - IgG
A Toxoplasma gondii - IgG test measures the presence of immunoglobulin G (IgG) antibodies specific to the Toxoplasma gondii parasite in the blood. These antibodies indicate a previous (past) exposure to the parasite. The presence of IgG antibodies indicates that you have had an infection, but it does not tell when. A high avidity in the IgG avidity test strongly suggests the infection happened more than 4 months ago. However, a low avidity result alone cannot be used to diagnose when the infection occurred, and further clinical evaluation is needed.
In general, having IgG antibodies to Toxoplasma gondii suggests a certain level of protection, but the effectiveness and duration of this protection can depend on factors such as the individual’s overall health, the strain of the parasite, and other immune-related considerations.
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Toxoplasma gondii - IgM
A Toxoplasma gondii - IgM test measures the presence of IgM antibodies in the blood, indicating recent or acute infection with the Toxoplasma gondii parasite. These antibodies are part of the body’s immune response and are produced when an individual is exposed to the parasite. These antibodies are the first to appear after being exposed to the parasite and may persist for up to 18 months post-infection. This test provides valuable information about recent exposure to Toxoplasma gondii, helping in the diagnosis and management of infections, especially in cases where timely detection is crucial.
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Rubella Virus - IgG
The Rubella Virus - IgG test measures the presence of Immunoglobulin G (IgG) antibodies specific to the rubella virus in an individual's blood. IgG antibodies are indicative of previous exposure or vaccination against rubella. This test helps assess an individual’s immunity status to the virus. If the IgG antibodies are detected, it suggests that the individual has either been vaccinated against rubella or has had a previous infection, leading to the development of immune protection.
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Rubella Virus - IgM
The Rubella Virus - IgM test determines the presence of Immunoglobulin M (IgM) antibodies in the blood against Rubella virus. IgM antibodies are the first line of defense produced by the immune system in response to a recent infection. Therefore, this test is crucial for diagnosing acute or recent rubella infections.
In acute primary infection during pregnancy, IgM may be detected 4-15 days after the rash appears. The IgM levels begin to decline after 36 -70 days and may last up to 180 days in some cases.
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Herpes Simplex Virus 1 & 2, IgG
A Herpes Simplex Virus 1 & 2, IgG test determines the presence of IgG antibodies against HSV-1 and HSV-2 in response to the Herpes infection. Your body begins to make two relevant types of HSV-1 antibody or HSV-2 antibody around 18 to 21 days after you are exposed to the virus and remains in the body for life. The presence of IgG antibodies generally indicates past exposure and immunity against Herpes infection. A Herpes Simplex Virus 1 & 2, IgG test also distinguishes whether the infection is caused by HSV-1 or HSV-2 type which provides essential information for the diagnosis, management, and prevention of HSV infection.
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Herpes Simplex Virus 1 & 2 IgM
The Herpes Simplex Virus 1 & 2 IgM test is designed to detect IgM antibodies that are produced as a body's first response to a HSV infection. IgM antibodies may take up to 10 days to develop. Also, these antibodies are usually present in higher concentrations shortly after an infection and eventually decrease after a time period (7-10 days). Therefore, the presence of HSV-1 or HSV-2 IgM antibodies typically suggests a recent infection.
Early detection allows doctors to detect symptoms quickly and provide necessary medical interventions to individuals suffering from HSV infection, leading to better outcomes and improved quality of life.
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Cytomegalovirus IgG Antibody
A Cytomegalovirus IgG Antibody test measures the presence of IgG antibodies in the blood, indicating a previous CMV infection. IgG antibodies are produced several weeks after the initial CMV infection. IgG levels rise during the active infection, then stabilize as the CMV infection resolves and the virus becomes inactive. Once exposed to CMV, you will have some measurable amount of CMV IgG antibody in your blood for the rest of your life, which provides protection from getting another primary infection (immunity). However, if you have a weak immune system, the virus can reactivate and cause serious symptoms or organ damage.
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Cytomegalovirus IgM Antibody
A Cytomegalovirus IgM Antibody test measures the presence of Immunoglobulin M (IgM) antibodies in the blood, specifically targeting the CMV. IgM antibodies are produced by the body first in response to a CMV infection. They can be detected in the blood within a week or two after the initial exposure. IgM levels rise for a short time, then decline and usually fall below detectable levels after a few months. IgM antibody levels rise again when latent CMV is reactivated.
Elevated levels of CMV IgM antibodies indicate an ongoing infection or recent exposure to the virus. Understanding the presence of IgM antibodies helps doctors diagnose and manage CMV infections effectively.
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