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Understanding the Test
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Interpreting Results
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References
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Dr. Betina Chandolia
BDS, MDS - Oral Pathology and Microbiology
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MBBS, MD (Pharmacology)
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Herpes Simplex Virus 1 & 2 IgM

Also known as Herpes Simplex Virus Type 1 & 2 IgM Antibody test
549700 21% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.

Understanding Herpes Simplex Virus 1 & 2 IgM


What is Herpes Simplex Virus 1 & 2 IgM?

A Herpes Simplex Virus 1 & 2 IgM test helps in determining recent exposure to Herpes simplex virus (HSV) 1 & 2 which causes herpes infection. It does so by detecting the presence of IgM antibodies (specific proteins) that are produced in response to a recently acquired infection. Early detection enables timely management and may also prevent further spread of the infection.

Herpes simplex virus (HSV), known as herpes, causes infections related to the skin. Herpes is highly contagious and can be spread through sexual contact or skin-to-skin contact with an infected person. The infection lasts a lifetime. Most HSV infections are asymptomatic or unrecognized, but symptoms of herpes include painful blisters or ulcers that can recur over time. Herpes is not curable, however, it can be well managed with medications. 

HSV-1 and HSV-2 are two strains of the herpes virus that can cause infections, usually related to the skin. HSV-1 is primarily associated with oral herpes, causing cold sores or blisters around the mouth and lips. It can spread through skin-to-skin contact such as kissing. Furthermore, HSV-2 causes genital herpes, resulting in painful sores and blisters in the genital area. It can spread through sexual contact and is considered a sexually transmitted disease. Therefore, Herpes Simplex Virus 1 & 2 IgM testing plays a vital role in identifying individuals with HSV 1 & 2 infections, including asymptomatic (those who do not show any symptoms) individuals who may unknowingly transmit the virus to others. 

Your doctor may recommend a Herpes Simplex Virus 1 & 2 IgM test when you are experiencing symptoms suggestive of herpes infection. Symptoms may include painful, recurring blisters or ulcers, painful urination, unusual discharge from the urethra and vagina, fever, body aches, sore throat, and swollen lymph nodes. This test specifically detects the presence of IgM antibodies in the blood, which are produced in response to an active or recent herpes infection. Also, a Herpes Simplex Virus 1 & 2 IgM test is used to confirm the presence of the virus during the early stages of infection or for individuals experiencing their first outbreak.

No special preparation is needed before undergoing a Herpes Simplex Virus 1 & 2 IgM test. Talk to your doctor about your specific test results. Narrate your complete medical history and symptoms to help them correlate your clinical and laboratory findings and formulate your treatment plan. It is important to communicate with your partners about the infection to ensure informed decisions regarding risk reduction. Negative results do not rule out the possibility of infection. Retesting is recommended after 8-14 days. 

What is Herpes Simplex Virus 1 & 2 IgM used for?

A Herpes Simplex Virus 1 & 2 IgM test is done: 

  • To confirm the diagnosis of herpes simplex virus (HSV) 1 & 2 infection in individuals with suggestive symptoms.

  • To find out if an individual is recently exposed to herpes infection.

  • To diagnose patients with a history of genital sores without any symptoms.

  • To identify a potential HSV infection in pregnant females without any relatable symptoms.

  • To detect the infection in your sexual partner if you are already infected.

  • To estimate and analyze the frequency of your symptoms and future outbreaks.

What does Herpes Simplex Virus 1 & 2 IgM measure?

The  Herpes Simplex Virus 1 & 2 IgM test is designed to detect IgM antibodies that are produced as a body's first response to a HSV infection. IgM antibodies may take up to 10 days to develop.  Also, these antibodies are usually present in higher concentrations shortly after an infection and eventually decrease after a time period (7-10 days). Therefore, the presence of HSV-1 or HSV-2 IgM antibodies typically suggests a recent infection.

Early detection allows doctors to detect symptoms quickly and provide necessary medical interventions to individuals suffering from HSV infection, leading to better outcomes and improved quality of life.

 

Interpreting Herpes Simplex Virus 1 & 2 IgM results


Interpretations

 

RESULT (INDEX)

REMARKS

< 0.8

Negative

0.8 - 1.2

Borderline

> 1.2

Positive

 

Negative results do not rule out the possibility of infection. Retesting is recommended after 8 - 14 days. 

Reference range may vary from lab to lab*

 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about Herpes Simplex Virus 1 & 2 IgM


Frequently Asked Questions about Herpes Simplex Virus 1 & 2 IgM

Q. Why is the Herpes Simplex Virus 1 & 2 IgM test ordered?

The Herpes Simplex Virus 1 & 2 IgM test is usually ordered when an individual experiences signs and symptoms suggestive of an HSV infection such as cold sores or genital sores. It is also performed when a person is at risk of the infection due to their lifestyle or certain medical conditions.

Q. Is there any risk associated with the Herpes Simplex Virus 1 & 2 IgM test?

The risks associated with the Herpes Simplex Virus 1 & 2 IgM test are minimal and may include slight pain or bruising at the site of the needle insertion. Rarely, a person may feel lightheaded or faint during the blood sample collection.

Q. Can a person be infected with both HSV-1 and HSV-2?

Yes, it's possible for an individual to have both HSV-1 and HSV-2 infections.

Q. Can asymptomatic individuals test positive for HSV-1 and HSV-2 IgM?

Yes, individuals with recent asymptomatic HSV infection can also test positive for HSV-1 and HSV-2 IgM IgM. That is why testing is crucial even in the absence of symptoms, especially in high-risk individuals.

Q. What are the symptoms of oral herpes?

The common symptoms of oral herpes include initial redness, swelling, heat, and pain, or itching in the area where the infection will erupt, cold sores, painful and fluid-filled blisters around lips, mouth or tongue.

Q. What are the symptoms of genital herpes?

The common symptoms of genital herpes include pain or itchiness along with small bumps/blisters around the genitals, painful ulcers, painful urination, or unusual discharge from the urethra and vagina.

Q. How common is genital herpes?

According to the World Health Organization (WHO), an estimated 491.5 million people aged 15-49 years were living with genital herpes as of 2016.

Q. How long does a herpes outbreak last?

Herpes outbreaks usually last for about one to two weeks, though the first outbreak after infection may last longer.

Q. Are symptoms of herpes virus infection the same for everyone?

No, many people infected with HSV have no symptoms. When symptoms do occur, they vary with each person. Some people have painful outbreaks with many sores. Others have only mild symptoms that may go unnoticed.

Q. What are the possible complications associated with HSV infections?

Possible complications associated with untreated or severe HSV infections include aseptic meningitis, encephalitis, neonatal herpes (if the mother has an active genital herpes infection during childbirth), and increased risk of HIV acquisition.

Q. How is herpes managed?

Herpes can be well managed with antiviral medications, especially during outbreaks. It is advised to take only prescribed medicines and do not self medicate.
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Herpes Simplex Virus 1 & 2 IgM test price for other cities


Price inBangaloreRs. 549
Price inKolkataRs. 549
Price inPuneRs. 549
Price inMumbaiRs. 549
Price inGurgaonRs. 549
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References

  1. Genital Herpes – CDC Basic Fact Sheet [Internet]. CDC; 03 Jan. 2022 [Accessed 18 Jan. 2024]. Available From: https://www.cdc.gov/std/herpes/stdfact-herpes.htm#:~:text=While%20herpes%20is%20not%20curable,your%20concerns%20and%20treatment%20options. External Link
  2. Genital Herpes Screening FAQ [Internet]. CDC; 11 Jul. 2022 [Accessed 18 Jan. 2024]. Available from: https://www.cdc.gov/std/herpes/screening.htm External Link
  3. Herpes simplex virus [Internet]. WHO; 05 Apr. 2023 [Accessed 18 Jan. 2024]. Available from: https://www.who.int/news-room/fact-sheets/detail/herpes-simplex-virus External Link
  4. Tada DG, Khandelwal N. Serum HSV-1 and 2 IgM in Sexually Transmitted Diseases - More for Screening Less for Diagnosis: An Evaluation of Clinical Manifestation. J Glob Infect Dis. 2012 Jul;4(3):S1-4. [Accessed 18 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459440/ External Link
  5. Nath P, Kabir MA, Doust SK, Ray A. Diagnosis of Herpes Simplex Virus: Laboratory and Point-of-Care Techniques. Infect Dis Rep. 2021 Jun 2;13(2):518-539. [Accessed 18 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8293188/ External Link
  6. Saleh D, Yarrarapu SNS, Sharma S. Herpes Simplex Type 1. [Updated 2023 Aug 28]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482197/ External Link
  7. Sauerbrei A. Herpes Genitalis: Diagnosis, Treatment and Prevention. Geburtshilfe Frauenheilkd. 2016 Dec;76(12):1310-1317. [Accessed 18 Jan. 2024]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5177552/ External Link
  8. Katz D, Hilliard JK, Mirkovic RR, Word RA. ELISA for detection of IgG and IgM antibodies to HSV-1 and HSV-2 in human sera. J Virol Methods. 1986 Aug;14(1):43-55. [Accessed 18 Jan. 2024]. Available from: https://pubmed.ncbi.nlm.nih.gov/3021796/ External Link

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