
Salmonella Typhi (Typhidot) IgG & IgM










A Salmonella Typhi (Typhidot) IgG & IgM test is done to detect the presence or absence of antibodies (IgG and IgM) against Salmonella typhi, the bacteria that causes typhoid fever. This is a rapid, easy-to-perform, user-friendly, accurate, and reliable test to identify a typhoid infection. Testing is important as some infected individuals may not exhibit any symptoms yet can spread the infection to others.













Understanding Salmonella Typhi (Typhidot) IgG & IgM
Typhoid fever, or enteric fever, is a bacterial infection that can spread throughout the body, affecting many organs. It is common in places with poor sanitation, lack of safe drinking water, food prepared in unhygienic conditions, and poor hygiene. Thus, access to safe/clean water, adequate sanitation, and hygiene among food handlers and typhoid vaccinators effectively prevent typhoid fever.
Typhoid manifests as fever, loss of appetite, stomach pain, diarrhea, and skin rash. You can get tested with a Salmonella Typhi (Typhidot) IgG & IgM test if you experience symptoms suggestive of typhoid, have been in contact with a typhoid patient, or have traveled to an area where typhoid is prevalent. Typhoid fever is a potentially serious and life-threatening infection if left untreated.
Rapid detection and appropriate treatment administration are essential to prevent typhoid outbreaks and severe complications, such as intestinal bleeding or perforation, hepatitis, shock, or pneumonia. Without prompt treatment, typhoid can be fatal. Since a Salmonella Typhi (Typhidot) IgG & IgM test does not require any special laboratory setting or equipment and provides specific, reliable, and easy-to-interpret test results, it is an extremely valuable diagnostic tool.
Usually, no special preparation is required for this test; you may eat and drink as per your daily routine. However, several factors can affect the accuracy of typhoid IgG and IgM tests, including the timing of the test, the quality of the testing materials, and the presence of interfering substances in the blood. False-positive results on the typhoid IgG antibody test can also occur in people who have received the typhoid vaccine or have previously been exposed to other strains of the Salmonella bacteria.
Talk to your doctor about your specific test results. Narrate your complete medical history to help them correlate your clinical and laboratory findings and formulate your treatment plan.
What does Salmonella Typhi (Typhidot) IgG & IgM measure?
Contains 2 testsA Salmonella Typhi (Typhidot) IgG & IgM test is an important diagnostic tool to diagnose typhoid fever. This test usually shows the infection within 2-3 days and detects IgM and IgG antibodies, illustrating a recent and a past infection respectively. When Salmonella typhi, the causative bacteria from typhoid, enters the body, your immune system, as a response, releases two types of antibodies (specific proteins), IgM and IgG, against the outer membrane protein of Salmonella typhi.
The Salmonella Typhi (Typhidot) IgG & IgM test is a qualitative rapid immunochromatographic test for the detection of Typhoid IgG and IgM antibodies.
The Salmonella Typhi (Typhidot) IgM test is an important and rapid diagnostic tool to diagnose typhoid fever. This test usually shows the typhoid infection within 2-3 days by detecting IgM antibodies, illustrating an active infection respectively. When Salmonella typhi enters the body, your immune system produces IgM antibodies as the body's first response of defense against the outer membrane protein of Salmonella typhi.
IgM antibodies are usually present in higher concentrations shortly after infection before gradually decreasing and eventually disappearing. Therefore, a positive IgM test for Salmonella Typhi typically suggests a recent or acute infection.
The Salmonella Typhi (Typhidot) IgM test is a qualitative rapid immunochromatographic test for the detection of Typhoid IgM antibodies.
Know more about Salmonella Typhi (Typhidot) IgM
The Salmonella Typhi (Typhidot) IgG test is performed to detect the presence or absence of IgG antibodies against Salmonella typhi, the bacteria that causes typhoid fever. IgG antibodies are the most frequent type of antibody, which are developed at a later stage, usually 2-3 weeks after the virus invades the body and causes the infection, and it remains in the body for life. Thus, IgG antibodies indicate if an individual has been infected with typhoid.
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FAQs related to Salmonella Typhi (Typhidot) IgG & IgM
- Typhoid [Internet]. WHO; 30 Mar. 2023 [Accessed 09 Oct. 2023]. Available from:
- Typhoid fever and parathyroid fever [Internet]. CDC; 22 Aug. 2018 [Accessed 30 Mar. 2023]. Available from:
- Typhoid fever [Internet]. NHS; 20 Sep. 2021 [Accessed 09 Oct. 2023]. Available from:
- Bhandari J, Thada PK, DeVos E. Typhoid Fever. [Updated 2022 Aug 10] [Internet]. Treasure Island, Florida: StatPearls Publishing; 2023 Jan. [Accessed 09 Oct. 2023]. Available from:
- Chernokhvostova E, Luxemburg KI, Starshinova V, Andreeva N, German G. Study on the production of IgG, IgA- and IgM-antibodies to somatic antigens of Salmonella typhi in humans. Clin Exp Immunol. 1969 Apr;4(4):407-21. [Accessed 09 Oct. 2023]. Available from:
- Marchello CS, Birkhold M, Crump JA. Complications and mortality of typhoid fever: A global systematic review and meta-analysis. J Infect. 2020 Dec;81(6):902-910. [Accessed 09 Oct. 2023]. Available from:
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