
PNH Advance near me in Indore







The PNH Advance test is a specialized blood test used to detect and confirm Paroxysmal Nocturnal Hemoglobinuria (PNH), a rare, acquired blood disorder. It works by identifying blood cells that lack protective surface proteins, making them more likely to break down (hemolyze). This test helps doctors diagnose PNH, assess its severity, and monitor the response to treatment. This test is widely available with Tata 1mg labs at an affordable price in Indore.








What does PNH Advance measure?
The PNH Advance measures the presence and proportion of blood cells that lack certain protective surface proteins, specifically CD55 and CD59. These proteins normally help safeguard red blood cells from being destroyed by the immune system’s complement pathway.
Using flow cytometry, a highly sensitive laboratory technique, this test can detect even a small number of defective cells and determine the PNH clone size, which indicates the percentage of blood cells affected by the condition. A larger clone size often suggests a more severe form of the disease and helps doctors evaluate disease progression, monitor response to treatment, and assess prognosis.
In some cases, the test also analyzes various types of blood cells, such as red blood cells, white blood cells, and platelets, to provide a more detailed assessment of how extensively PNH affects the blood system.





- Brando B, Gatti A, Preijers F. Flow Cytometric Diagnosis of Paroxysmal Nocturnal Hemoglobinuria: Pearls and Pitfalls - A Critical Review Article. EJIFCC. 2019 Nov 25;30(4):355-370. PMID: 31814811; PMCID: PMC6893893. [Accesses 06 Nov. 2025]. Available From:
- Mishra P, Tripathi P, Halder R, Saxena R, Tyagi S, Mahapatra M, Pati HP. Clinico-Hematological Profile of Paroxysmal Nocturnal Hemoglobinuria in Indian Patients: FLAER Flow Cytometry Based Experience from an Indian Tertiary Care Centre. Indian J Hematol Blood Transfus. 2021 Apr;37(2):220-225. [Accesses 06 Nov. 2025]. Available From:
Other tests
- TCS Wellness Package ECG Camp in Indore
- Comprehensive Gold Full Body Checkup with Smart Report in Indore
- Comprehensive Silver Full Body Checkup with Smart Report in Indore
- Good Health Gold Package with Smart Report in Indore
- CBC (Complete Blood Count) in Indore
- Comprehensive Check-up in Indore
- TCS Wellness Package Pathology Camp in Indore
- Vitamin D (25-Hydroxy) & Vitamin B12 in Indore
- Vitamin B12 in Indore
- Wellbeing Check-up in Indore
- CBC (Complete Blood Count) in Indore
- CRP (C-Reactive Protein), Quantitative in Indore
- Complete Hemogram (CBC & ESR) in Indore
- Serum Ferritin in Indore
- ESR (Erythrocyte Sedimentation Rate) in Indore
- Blood Group ABO & Rh Factor in Indore
- Hb (Hemoglobin) in Indore
- PT INR (Prothrombin Time with INR) in Indore
- HIV 1 and 2 Antibody, Rapid Screening Test in Indore
- Viral Marker Screening (HIV, HBsAg, Anti-HCV) in Indore
- Total IgE in Indore
- Rheumatoid Factor - Quantitative in Indore
- Serum Iron Studies Basic in Indore
- Hemoglobin HPLC / Electrophoresis in Indore
- hsCRP (High Sensitive CRP) in Indore
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)














