Understanding PNH Advance
What is PNH Advance?
The PNH (Paroxysmal Nocturnal Hemoglobinuria) test is a diagnostic blood test used to detect and confirm the presence of PNH, a rare acquired disorder of the blood. This test typically involves flow cytometry, which examines the patient's blood cells for the absence or deficiency of certain proteins (CD55 and CD59) on the cell surface. A deficiency in these proteins makes blood cells more susceptible to premature destruction. The PNH test aids in diagnosing PNH, assessing its severity, and guiding treatment decisions for affected individuals.