Microsatellite Instability (MSI) by Fragment Analysis
MSI, or Microsatellite Instability, is a genetic phenomenon in cancer where DNA repair mechanisms malfunction. This instability can be exploited in cancer treatment, as drugs like immunotherapy are effective against MSI-high tumors, offering promising prospects for more targeted and personalized cancer therapies.
In tandem, the Microsatellite Instability Assay scrutinizes DNA samples using multiplex PCR and fragment analysis across 13 mononucleotide markers, in accordance with NCI guidelines. Notably, markers such as BAT-25, BAT-26, and BAT-40 are meticulously selected to ensure the highest sensitivity.
Disclaimer: In no event shall the liability of TATA 1MG exceed the amount of actual cost of test charges incurred by the customer as stated on the invoice issued by Tata 1mg.
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