Hypersensitive Pneumonitis Profile - Basic

Hypersensitive pneumonitis (HP), or extrinsic allergic alveolitis, is an inflammatory lung condition. It occurs due to repeated exposure to environmental allergens (antigens) such as mold, fungal spores, bird droppings, and other organic particles. This repeated exposure can cause abnormal immune reactions, resulting in inflammation in the alveoli (small air spaces of the lungs) and impairing the function of the lungs.

The Hypersensitive Pneumonitis Profile - Basic tests for certain immunoglobulin G (IgG) antibodies against a variety of common allergens associated with hypersensitivity pneumonitis. These include:

• Penicillium chrysogenum: a widespread indoor mold that grows in moist places. 
• Cladosporium herbarum: a common airborne fungus responsible for respiratory allergies. 
• Mucor racemosus: an occupational HP-related soil-borne mold. 
• Alternaria alternata: a fungal species of allergen that worsens respiratory conditions.
• Aspergillus fumigatus: a fungus responsible for allergic and hypersensitive lung disease. 
• Pigeon serum proteins, feathers, and droppings: common allergens in individuals exposed to birds, frequently present in "bird fancier's lung.

This panel is tailored to identify sensitization to particular environmental antigens, helping diagnose HP. It is particularly beneficial for those with symptoms like chronic cough, dyspnea, and fatigue, especially if they are exposed to birds, mold, or dust at work or home. Doctors may also order this test for individuals who have recurrent pneumonia or pneumonitis. The panel is also vital for diagnosing diffuse interstitial lung disease (ILD) when HP is suspected. Early diagnosis is necessary to prevent severe complications such as lung scarring (pulmonary fibrosis) or compromised lung function due to restrictive lung disease.

No special preparation is required for the test. Additionally, patients should inform their doctor about any medications being taken or any recent infections, as these can affect results.

Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Do not self-medicate, and always consult a doctor to understand the test results correctly.

Please note: This is an outsourced test. The sample for this test is collected by TATA 1MG and processed at a NABL accredited partnered lab.