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TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum

TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum

Also referred as
Ultra CBNAAT
MTB/RIF Ultra
MTB-Xpert
+1
Xpert MTB/RIF Ultra for pulmonary tuberculosis and rifampicin resistance
135+ booked recently
For men & women
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The TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum test is a rapid, cartridge-based molecular diagnostic platform (CBNAAT) that uses automated PCR technology to detect Mycobacterium tuberculosis (MTB), the bacteria that causes tuberculosis (TB). Simultaneously, it also detects, it is done to find out if the TB bacteria are resistant to rifampicin, one of the main medicines used to treat TB. The advanced technology is significantly faster than traditional methods.

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Understanding TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum

Tuberculosis (TB) is a contagious infection caused by Mycobacterium tuberculosis, mainly affecting the lungs. It spreads through the air when someone with active TB coughs, sneezes, or speaks. Early and accurate diagnosis is essential to begin timely treatment and prevent the spread of the disease.

The TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum test is an advanced molecular diagnostic test designed to detect the presence of Mycobacterium tuberculosis (MTB) in a sputum sample. This test uses the Xpert MTB/RIF Ultra assay on the GeneXpert Instrument System for rapid and precise detection of MTB complex DNA. If TB is detected, the test also checks for rifampicin resistance by identifying mutations in the rpoB gene. Rifampicin resistance is a key indicator of multidrug-resistant TB (MDR-TB) and indicates that further testing may be required.

This test is best suited for patients with clinical suspicion of tuberculosis (TB) when used in conjunction with clinical and other laboratory findings. Testing helps in early initiation of TB treatment and assists in guiding personalized TB therapy. Additionally, this panel aids in monitoring treatment response and assessing the risk of transmitting TB to others. This technology is highly sensitive in comparison to smear microscopy, enabling more people with MTB infections to be detected and treated earlier.

Collect sputum in a sterile, leak-proof container with a screw-cap lid. Before collecting the sample, rinse your mouth with clean water. Take two to three deep breaths, then cough deeply to bring up sputum from the lungs. Ensure you collect at least 2 ml of thick, yellowish (muco purulent) sputum. Avoid collecting only saliva or nasal secretions. As per National Tuberculosis Elimination Programme (NTEP) guidelines, testing requires two sputum samples. This may include a spot and early morning sample collected on consecutive days, or two spot samples collected one hour apart, for accurate diagnosis of tuberculosis (TB).

Laboratory test results may vary across laboratories. Do not self-medicate and always consult a doctor to understand the test results correctly.

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What does TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum measure?

The TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum test measures the presence of Mycobacterium tuberculosis (MTB) DNA in a sputum sample using advanced molecular technology. If TB bacteria are detected, the test also checks for mutations in the rpoB gene, which are associated with resistance to rifampicin, a key first-line drug used in TB treatment. Rifampicin resistance is often an indicator of multidrug-resistant TB (MDR-TB). By detecting both the TB bacteria and potential drug resistance, the test helps in identifying not only the infection but also the type of treatment that may be required for effective management.

FAQs related to TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum

The TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum test is used to detect tuberculosis (TB) in a sputum sample and check if the TB bacteria are resistant to rifampicin, a key TB medicine.
CBNAAT stands for Cartridge Based Nucleic Acid Amplification Test. It is an advanced molecular test to detect TB and rifampicin resistance using nucleic acid amplification.
It helps in early diagnosis of TB and shows if the infection is drug-resistant. This allows doctors to start the right treatment as soon as possible.
A sputum sample (mucus coughed up from the lungs) is needed for this test.
No, fasting is not required for this test.
No, you only need to cough up sputum into a container. There are no needles or injections involved.
People with symptoms like long-term cough, fever, chest pain, weight loss, or night sweats, or those who are in contact with a TB patient, may be advised to take this test.
Rifampicin is one of the main antibiotics used to treat TB. It helps kill the TB bacteria when taken as part of a combination therapy.
Rifampicin resistance means the TB bacteria in the body have developed resistance to rifampicin, making the medicine less effective. This condition is often a sign of multidrug-resistant TB (MDR-TB) and may require additional tests.
Yes, but it usually requires longer and more complex treatment with different antibiotics/Anti-tubercular drugs. Early detection and proper treatment increase the chances of recovery.
Yes, TB can come back if treatment is not completed or if reinfection occurs. That is why it is important to finish the full course of medication as prescribed by a doctor.
Yes, early diagnosis, proper treatment, vaccination (BCG for children), and avoiding close contact with infected individuals help prevent TB.
Standard TB tests, like sputum smear microscopy, detect TB bacteria under a microscope, but they can miss cases with low bacterial count. The TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum test uses advanced molecular technology to detect TB DNA and rifampicin resistance more accurately and quickly.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
Content created by
Written by:
Shweta Prakash
MSc, BSc
Reviewed by:
Dr. Trupthi Gowda
MD Microbiology, MBBS
Want to know moreRead our editorial policy
Last Updated6th Dec 2025

TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum test price for other cities

Price inBangaloreRs. 2400
Price inMumbaiRs. 2400
Price inNew DelhiRs. 2400
Price inKolkataRs. 2400
Price inPuneRs. 2400

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TB Detection by GeneXpert Ultra MTB with Rifampicin Resistance, Sputum