Hepatitis B Surface Antigen, Serum
Understanding Hepatitis B Surface Antigen, Serum
What is Hepatitis B Surface Antigen, Serum?
A Hepatitis B Surface Antigen, Serum test detects the presence of hepatitis B virus (HBV) and also measures the amount of hepatitis B surface antigen (HBsAg) in the blood. The test helps determine a recent or long-standing infection due to HBV. In addition, this test also helps monitor the ongoing antiviral treatment for hepatitis B in affected individuals.
Hepatitis B is a viral infection that affects the liver and causes liver inflammation. It is transmitted when the blood, semen, or other body fluids from an infected person enter the body of someone who is not infected. This can happen through sexual contact; by sharing needles, syringes, or other drug-injection equipment; due to infected blood transfusion; or during pregnancy or delivery. Hepatitis B vaccination is the safest and most effective practice to prevent this infection.
HBV has proteins called antigens on its surface that cause your immune system to make antibodies. Hepatitis B surface antigens can be found in your blood within several weeks after the infection starts. These antigens are one of the earliest markers of a hepatitis B infection. Following initial infection, most of the infected individuals do not exhibit any symptoms. However, some of the common symptoms are fever, nausea, vomiting, loss of appetite, stomach pain, joint pain, dark-colored urine, light-colored stool, and the yellowing of skin and eyes.
A Hepatitis B Surface Antigen, Serum test quantifies or measures the levels of HBsAg in the blood, allowing doctors to assess the stage of the infection and start appropriate treatment. This test helps to identify inactive carriers of HBV and evaluate the risk of infection progression in chronic (prolonged) hepatitis B patients. A Hepatitis B Surface Antigen, Serum may also be done to distinguish between various infection stages and ascertain whether the virus is replicating. It is recommended for patients diagnosed with hepatitis B infection by PCR testing or qualitative Hepatitis B antigen.
Usually, no special preparation is needed for this test. You may eat and drink as per your daily routine. Talk to your doctor about your specific test results. Discuss your complete medical history and symptoms to help them correlate your clinical and laboratory findings. The test results will help the doctor determine your medical condition and make informed decisions regarding the course of treatment.
What is Hepatitis B Surface Antigen, Serum used for?
A Hepatitis B Surface Antigen, Serum test is done to:
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Screen for hepatitis B infection if an individual has been exposed to HBV or has symptoms associated with liver disease.
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Prevent transmission of HBV to recipients of blood, blood components, cells, tissue, and organs.
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Helps identify inactive carriers and evaluate the risk of infection progression in chronic hepatitis B patients.
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Distinguish between the various infection stages and detects whether the hepatitis B virus is replicating in the blood.
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To check treatment or antiviral medicines response against hepatitis B infection.
What does Hepatitis B Surface Antigen, Serum measure?
A Hepatitis B Surface Antigen, Serum test checks and measures the amount of hepatitis B surface antigen (HBsAg) in an infected individual, particularly with chronic hepatitis B infection. HBsAg is the first serological marker, within 1 to 10 weeks, to appear in the blood after recent exposure to HBV. Persistence of this marker for more than 6 months implies chronic (long-term) HBV infection which may lead to liver damage (scarring or cirrhosis). A person who has a chronic infection is capable of spreading the infection to healthy individuals, even if they do not show or experience any symptoms.