
D-Dimer










A D-Dimer test detects the presence of D-dimer, a protein fragment produced when a blood clot dissolves in the body. This test helps diagnose and monitor conditions related to blood clot formation, such as deep vein thrombosis (DVT), pulmonary embolism (PE), stroke and disseminated intravascular coagulation (DIC).













Understanding D-Dimer
During an injury, the body uses proteins to clot the blood and stop bleeding. Once the bleeding stops, the body sends other proteins to break down the clot slowly. D-dimer is a protein fragment generated during the breakdown of blood clots. A D-Dimer test determines the presence of D-dimer and helps assess the blood clot formation and breakdown in the body.
This test may be needed in individuals presenting with symptoms suggestive of blood clots, such as leg swelling, pain, redness, shortness of breath, chest pain, rapid heartbeat, or signs of abnormal bleeding. Higher than normal D-dimer levels can indicate the presence of an active blood clot, and hence, a D-Dimer test helps diagnose or rule out blood clot-related conditions such as DVT, PE, stroke, and DIC. Sometimes, this test is also used to monitor the effectiveness of treatment for these conditions. In addition, a D-dimer test also helps understand the risk and progression in cases of pneumonia and COVID-19.
No fasting is required for this test. You can eat and drink normally as per your routine. However, a duly filled coagulation requisition form is mandatory for sample collection. Before getting tested, let your doctor know if you are taking any medications, as they might interfere with the test results, and you may have to stop taking them for some time.
Test result ranges are approximate and may differ slightly between labs depending on the methodology and laboratory guidelines. Talk to your doctor about your specific test results to understand your condition, and narrate your complete medical history to your doctor to help formulate an effective treatment plan.
What does D-Dimer measure?
A D-Dimer test measures the amount of D-dimer protein your body produces when a blood clot begins to break down. It is a byproduct of the blood clotting and clot break-down process that can be measured by analyzing a blood sample. D-dimer is typically undetectable in the blood and is produced only after a clot has formed and is broken down.





FAQs related to D-Dimer
- D-dimer test [Internet]. Healthdirect; Dec. 2022 [Accessed 10 Oct. 2023]. Available from:
- D-dimer [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 10 Oct. 2023]. Available from:
- Gutiérrez García I, Pérez Cañadas P, Martínez Uriarte J, García Izquierdo O, Angeles Jódar Pérez M, García de Guadiana Romualdo L. D-dimer during pregnancy: establishing trimester-specific reference intervals. Scand J Clin Lab Invest. 2018 Oct;78(6):439-442. [Accessed 10 Oct. 2023]. Available from:
- Bounds EJ, Kok SJ. D Dimer. [Updated 2023 Jul 10]. [Internet]. Treasure Island, Florida: StatPearls Publishing; 2023 Jan. [Accessed 10 Oct. 2023]. Available from:
- Kabrhel C, Mark Courtney D, Camargo CA Jr, Plewa MC, Nordenholz KE, Moore CL, Richman PB, Smithline HA, Beam DM, Kline JA. Factors associated with positive D-dimer results in patients evaluated for pulmonary embolism. Acad Emerg Med. 2010 Jun;17(6):589-97. [Accessed 10 Oct. 2023]. Available from:
Other tests
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)























