Test Detail
Understanding the Test
Test Measures
Interpreting Results
FAQ's
City Price Info
Home Collection
References
Other Tests
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Dr. Shreya Gupta
BDS, MDS - Oral and Maxillofacial Pathology
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CA19.9

Also known as Pancreatic Cancer Marker, Cancer Antigen-GI
10991500 26% Off
You need to provide
Blood
This test is for
Male, Female
Test Preparation
  1. No special preparation is required.
  2. Provide brief clinical history/ doctor's prescription at the time of sample collection.

Understanding CA19.9


What is CA19.9?

A CA19.9 test measures the levels of a specific protein called cancer antigen (CA19.9) in the blood. This protein is associated with certain types of cancer, most notably affecting the pancreas.

CA19.9, a glycoprotein, is an important biomarker that helps in the identification and management of specific cancers, primarily focusing on pancreatic cancer. Given the challenges in diagnosing pancreatic cancer early, CA19.9 test plays a vital role in its detection and monitoring. 

Elevated levels of CA 19.9 in the blood are frequently associated with pancreatic tumors, and this biomarker is integral in differentiating between benign and malignant conditions in the pancreas. However, it is noteworthy that elevated levels can also be seen in various other cancers, including colorectal, gastric, hepatobiliary, and ovarian cancer. Additionally, the levels of CA 19.9 may be elevated in non-cancerous conditions such as pancreatitis, cirrhosis, and benign gallbladder disease. This underscores the importance of interpreting CA 19.9 results in the broader clinical context, considering various factors that may influence its levels. While CA 19.9 is a valuable marker in cancer management, it is important to note that it is not a standalone test, other confirmatory procedures such as imaging studies or biopsies, are often necessary to validate cancer diagnosis. CA19.9 test, when integrated into a comprehensive clinical approach, contributes significantly to the timely identification and treatment of cancers, ultimately impacting treatment outcomes.

No special preparations are required before undergoing a CA19.9 test. However, it is important to provide a brief clinical history or doctor's prescription at the time of sample collection.  

Lab test results may vary across different laboratories. Abnormal test results require an expert interpretation; therefore, never try to self-medicate at home based solely on these results, and always consult a doctor for a proper understanding of the test results. Doctors use the CA19.9 test not only for diagnostic purposes but also for monitoring cancer progression, assessing treatment response, and detecting potential cancer recurrence. 

What is CA19.9 used for?

A CA19.9 test is done: 

  • As an adjunct to other diagnostic tests to aid in the detection of pancreatic cancer.

  • To screen for other cancers, such as colorectal, gastric, hepatobiliary, ovarian cancer, etc.

  • To differentiate between benign and malignant conditions in the pancreas and other related organs.

  • To monitor cancer progression and assess the treatment response.

  • To detect potential cancer recurrence. 

  • To monitor other non-cancerous conditions like pancreatitis, cirrhosis, etc.

What does CA19.9 measure?

The CA19.9 test measures the level of a specific tumor marker called CA 19.9 in the blood, often associated with gastrointestinal cancers, particularly pancreatic cancer. This biomarker is produced by certain cells in the body, specifically epithelial cells. These cells are found in various tissues, including the gastrointestinal tract. Elevated levels of CA 19.9 are often associated with cancers that involve these tissues, such as pancreatic, colorectal, and gastric cancers. However, CA 19.9 can also be produced by non-cancerous conditions, impacting its specificity as a diagnostic marker. For a comprehensive evaluation, it is advised to consider other diagnostic tests in conjunction with CA19.9 test and consult a doctor for a proper understanding of the test results.

Interpreting CA19.9 results


Interpretations

 

Disease

%age positivity of CA 19-9

Pancreatic cancer

80

Hepatobiliary cancer

67

Gastric cancer

40 - 50

Hepatocellular cancer

30 - 50

Colorectal cancer

30

Breast cancer

15

Pancreatitis

10 - 20

Benign gastrointestinal diseases

10 - 20

 

 

Answers to Patient Concerns & Frequently Asked Questions (FAQs) about CA19.9


Frequently Asked Questions about CA19.9

Q. When should I get the CA19.9 test?

Get a CA19.9 test when recommended by your doctor, typically if you have symptoms or risk factors associated with gastrointestinal cancers, particularly pancreatic cancer. It is a part of a comprehensive evaluation and not a routine screening test.

Q. Is there any risk associated with a CA19.9 test?

No, there is no risk associated with CA19.9. However, some individuals may feel a slight sting when a needle is pricked and experience some bleeding that is normal and usually not bothersome. Rarely, some individuals may also experience slight swelling or bruising at the site of the needle prick. Applying ice 3-4 times a day for about a week may help reduce swelling and bruising. If it does not get better, consult your doctor.

Q. Is CA19.9 test a definitive diagnostic test for pancreatic cancer?

No, CA19.9 test is not a definitive test for pancreatic cancer. Elevated levels can indicate various conditions. A comprehensive evaluation, including imaging and clinical assessment, is necessary for establishing a proper diagnosis.

Q. What factors can affect my CA 19.9 levels?

CA 19.9 levels can be influenced by various factors, including non-cancerous conditions like pancreatitis, as well as lifestyle choices such as alcohol consumption and smoking. Always consult a doctor for a comprehensive interpretation of your test results based on your individual condition.

Q. What are the signs and symptoms of pancreatic cancer?

The common signs and symptoms of pancreatic cancer include abdominal pain, jaundice, unexplained weight loss, changes in stool color, and other digestive problems. However, these symptoms can be caused by various other conditions as well.

Q. What are the risk factors of pancreatic cancer?

The common risk factors of pancreatic cancer include obesity, diabetes, unhealthy food choices, alcohol, smoking, pancreatitis, or a family history of pancreatic cancer.
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CA19.9 test price for other cities


Price inMumbaiRs. 1099
Price inBangaloreRs. 1099
Price inKolkataRs. 1099
Price inGurgaonRs. 1099
Price inPuneRs. 1099
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References

  1. CA 19-9 [Internet]. Rochester, NY: University of Rochester Medical Center; [Accessed 20 Dec. 2023]. Available from: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=207&contentid=ca_19_9 External Link
  2. Ballehaninna UK, Chamberlain RS. The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal. J Gastrointest Oncol. 2012 Jun;3(2):105-19. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397644/ External Link
  3. Ballehaninna UK, Chamberlain RS. Serum CA 19-9 as a Biomarker for Pancreatic Cancer-A Comprehensive Review. Indian J Surg Oncol. 2011 Jun;2(2):88-100. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3244191/ External Link
  4. Puckett Y, Garfield K. Pancreatic Cancer. [Updated 2022 Sep 26]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK518996/ External Link
  5. Vincent A, Herman J, Schulick R, Hruban RH, Goggins M. Pancreatic cancer. Lancet. 2011 Aug 13;378(9791):607-20. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062508/ External Link
  6. Zhao Z, Liu W. Pancreatic Cancer: A Review of Risk Factors, Diagnosis, and Treatment. Technol Cancer Res Treat. 2020 Jan-Dec;19:1533033820962117. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768873/ External Link
  7. Wu E, Zhou S, Bhat K, Ma Q. CA 19-9 and pancreatic cancer. Clin Adv Hematol Oncol. 2013 Jan;11(1):53-5. PMID: 23596673; PMCID: PMC3633106. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3633106/ External Link
  8. Ballehaninna UK, Chamberlain RS. Serum CA 19-9 as a Biomarker for Pancreatic Cancer-A Comprehensive Review. Indian J Surg Oncol. 2011 Jun;2(2):88-100. [Accessed 20 Dec. 2023]. Available from: https://pubmed.ncbi.nlm.nih.gov/22693400/External Link
  9. Wang F, Herrington M, Larsson J, Permert J. The relationship between diabetes and pancreatic cancer. Mol Cancer. 2003 Jan 6;2:4. [Accessed 20 Dec. 2023]. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC149418/External Link

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