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Autoimmune Encephalitis Profile - 2

Also referred as
NMDA test
+7
AMPA test
GluR1 and GluR 2 test
GABA B receptor test
VGKC test
LG1 test
CASPR2 test
DPPX test
For men & women
Earliest reports in
192 hours
Contains
6 tests
Test price:
₹33030
₹36700
10% off
Get it at ₹31530 with coupon
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The Autoimmune Encephalitis Profile - 2 is a blood test that looks for specific antibodies in your blood. These antibodies can attack your brain, causing a condition called autoimmune encephalitis, which leads to inflammation and brain dysfunction.

 

Samples required
Blood
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Why is this test booked?
Preparations
No special preparation is required.
Sample Collection
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Conducted by
NABL accredited partner lab
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Highly skilled Phlebos
Verified reports
Who will collect your samples?
Tata 1mg certified phlebotomists
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NABL accredited partner lab
This is an outsourced test. The sample for this test is collected by Tata 1mg and processed at a NABL-accredited partner lab.
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Understanding Autoimmune Encephalitis Profile - 2

Autoimmune encephalitis is a serious but rare condition in which your own immune system attacks the brain, leading to inflammation and a wide range of neurological and psychiatric symptoms. These can include memory loss, confusion, seizures, hallucinations, or changes in behavior and mood.

The Autoimmune Encephalitis Profile - 2 helps doctors detect specific antibodies known to cause this condition, including those that target brain receptors like NMDA, AMPA, and GABA-B, as well as other antibodies like VGKC (LGI1 & CASPR2) and DPPX. Finding these antibodies helps confirm a diagnosis of autoimmune encephalitis after other causes, such as infections, have been ruled out.

Early and accurate diagnosis is critical, as the condition can be treated with therapies that help suppress the immune system.

Your doctor may recommend the Autoimmune Encephalitis Profile - 2 test if you have new or unexplained neurological symptoms. These symptoms can include seizures of unknown origin, hallucinations or confusion, and new or worsening neuropsychiatric symptoms. The test may also be recommended for patients with certain tumors who show signs of encephalitis (brain inflammation) or those with neuromyotonia (a disorder that causes muscle stiffness and continuous muscle activity). It is often performed with other tests to get a complete picture of your health.

No special preparation is needed for this test. However, you should inform your doctor about all medications and supplements you are taking, as they could affect the results.

Test result ranges are approximate and may differ slightly between labs depending on the methods and guidelines. Do not self-medicate, and always consult a doctor to understand the test results correctly.

Please note: This is an outsourced test. The sample is collected by TATA 1MG and processed at a NABL accredited partnered lab.

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What does Autoimmune Encephalitis Profile - 2 measure?

Contains 6 tests

The Autoimmune Encephalitis Profile - 2 measures the levels of several specific antibodies in the blood that are known to cause autoimmune encephalitis. These include:

  • Voltage-Gated Potassium Channel antibody (VGKC) 
  • N-methyl-D-aspartate (NMDA) receptor antibodies
  • α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antibodies
  • Gamma-aminobutyric acid type B (GABA-B) receptor antibodies
  • Dipeptidyl-peptidase-like protein 6 (DPPX) antibodies

The presence of these antibodies suggests that the immune system is mistakenly attacking the brain.

The VGKC Antibody test measures the presence and concentration of antibodies directed against voltage-gated potassium channels (VGKC) associated proteins (Leucine-rich glioma inactivated protein 1(LGI1) and Contactin-associated protein 2 (CASPR2) in the blood. These antibodies indicate that the immune system is mistakenly attacking nerve cells, which can disrupt normal nerve signaling.

Elevated VGKC antibody levels may suggest autoimmune neurological disorders such as limbic encephalitis, Morvan’s syndrome, or neuromyotonia. Detecting and quantifying these antibodies helps doctors confirm the diagnosis, guide treatment strategies, and monitor the effectiveness of immunotherapy. Low or undetectable levels typically indicate that VGKC-mediated autoimmune activity is unlikely.

Know more about VGKC Antibody

NMDA (anti-glutamate receptor against NR1 subunit)
AMPA(anti-glutamate)-GluR1
AMPA(anti-glutamate)-GluR2
GABA-B receptor antibody
DPPX by IFA
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Autoimmune Encephalitis Profile - 2 test price for other cities

Price inMumbaiRs. 29701
Price inKolkataRs. 33030
Price inJodhpurRs. 33030
Price inBangaloreRs. 33030
Price inAsansolRs. 33030
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FAQs related to Autoimmune Encephalitis Profile - 2

The Autoimmune Encephalitis Profile - 2 is a blood test that checks for specific antibodies that attack the brain, which can cause a serious condition called autoimmune encephalitis.
No, fasting is not required for this test.
A blood sample is taken from a vein in your arm, and the lab tests it for the presence of specific antibodies.
The test is safe with minimal risks. You may have some discomfort, bruising, or swelling at the blood draw site.
People with unexplained seizures, memory problems, confusion, or changes in behavior may have an autoimmune condition affecting the brain.
A positive result means that the tested antibodies were found in your blood. This supports a diagnosis of autoimmune encephalitis and helps the doctor choose the best treatment.
Yes, it is possible. This panel only tests for some of the known antibodies. Your doctor will consider all your symptoms and other test results to make a diagnosis.
Tata 1mg ensures accurate lab test results through certified laboratories that use advanced technology and adhere to stringent quality control measures. This commitment to high standards guarantees reliable results.
Recommended for everyone
This package is designed with everyone’s overall health considerations in mind, offering assessments to address a wide range of wellness needs.
Package can be booked by :
Men
Women
Contains 6 tests
VGKC Antibody
NMDA (anti-glutamate receptor against NR1 subunit)
AMPA(anti-glutamate)-GluR1
AMPA(anti-glutamate)-GluR2
GABA-B receptor antibody
DPPX by IFA
Report delivery
Standard time
192 hrs
For slots after 11 AM, report will be delivered in 216 hours.
Samples required
Blood
Our phlebotomist will draw a blood sample, typically from a vein in your inner elbow.
Preparations
1
No special preparation is required.
Why is this test booked?
1
To help diagnose autoimmune encephalitis in patients with unexplained neurological symptoms
2
To distinguish autoimmune encephalitis from other types of encephalitis (brain inflammation)
3
To identify the specific type of antibody involved, which can help guide treatment
4
To monitor treatment response
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