Anti - Neutrophil Cytoplasmic Antibodies (ANCA) by IFA near me in Bangalore

The MPO (p-ANCA) test detects antibodies in the blood that target myeloperoxidase (MPO), a protein found in certain white blood cells. These antibodies are commonly associated with autoimmune diseases like Microscopic Polyangiitis (MPA) and Churg-Strauss Syndrome, which cause inflammation in small blood vessels. A positive MPO (p-ANCA) test helps doctors diagnose these conditions, differentiate them from other similar health issues, and guide appropriate treatment for better management.

The PR3 (c-ANCA) test detects antibodies in the blood that target proteinase-3 (PR3), a protein found in certain white blood cells. These antibodies are commonly associated with autoimmune diseases like Granulomatosis with Polyangiitis (GPA), which causes inflammation in blood vessels and affects organs such as the kidneys, lungs, and sinuses. A positive PR3 (c-ANCA) test helps doctors diagnose these conditions, distinguish them from other similar health issues, and guide the appropriate treatment for better disease management.

The Atypical ANCA (Anti-Neutrophil Cytoplasmic Antibodies) test measures the presence of specific antibodies in the blood that target proteins in neutrophils, a type of white blood cell. These antibodies are often linked to autoimmune conditions such as Churg-Strauss Syndrome, Ulcerative Colitis, autoimmune hepatitis and certain types of vasculitis. Unlike the typical ANCA test, which detects antibodies against proteins like proteinase 3 (PR3) and myeloperoxidase (MPO), the atypical ANCA test looks for antibodies against other antigens. This test is primarily used in diagnosing autoimmune conditions like vasculitis, particularly those that may not show up with other ANCA testing, helping doctors identify and manage these conditions more accurately.