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Thyroxine Binding Globulin

5000
4.8
NABL, CAP
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Overview
Interpretations
FAQ's
Thyroxine Binding Globulin

Overview of Thyroxine Binding Globulin

What is Thyroxine Binding Globulin?

Thyroxine Binding Globulin (TBG) test is done to assess the thyroid tissues. It helps in the diagnosis of other thyroid disorders such as hypothyroidism and hyperthyroidism. T3 (Triiodothyronine) and T4 (Thyroxine) hormones are produced by the thyroid gland which binds with the proteins produced by the body. However, small amounts of T3 and T4 remains ‘free’ as it does not bind with the proteins. The protein bound T3 and T4 binds to TBG. This test measures the levels of TBG which helps in assessing thyroid problems.

Sample Type

The sample type collected for Thyroxine Binding Globulin is: Blood

Preparation for Thyroxine Binding Globulin

  • No special preparation required

Why Get Tested for Thyroxine Binding Globulin?

  • To diagnose hypothyroidism (low levels of thyroid)

  • To diagnose hyperthyroidism (high levels of thyroid)

  • To monitor treatment in patients with thyroid disease

Understand more about Thyroxine Binding Globulin

TBG is a serum binding protein which has a high affinity to bind to T3 and T4. In the routine, the thyroid gland maintains the level of free hormone i.e. which is not bound to the TBG. This test is done to assess the thyroid tissues. It helps in diagnosing thyroid disorders such as hypothyroidism and hyperthyroidism. The rise in levels is associated with the intake of oral contraceptives or estrogen therapy. In conditions such as pregnancy or if a person has family history elevated levels of TBG are seen. The decrease in TBG levels is associated with intake of androgenic steroids, heavy doses of glucocorticoids, liver disease, nephrotic syndrome, congenital TGB variants and hypoproteinemic states.  


What Results of Thyroxine Binding Globulin mean?

Interpretations

High levels may indicate:

  • Liver disease

  • Acute intermittent porphyria

  • Hypothyroidism


Low levels may indicate:

  • Acromegaly

  • Acute illness

  • Hyperthyroidism

  • Malnutrition

  • Nephrotic Syndrome


Patient Concerns about Thyroxine Binding Globulin

Frequently Asked Questions about Thyroxine Binding Globulin

Q. What is Hyperthyroidism?
Hyperthyroidism is a condition in which the thyroid gland is overactive and there is an increased production of thyroid hormones by the thyroid gland. Causes of Hyperthyroidism include Graves’ disease, multinodular goiter, thyroid nodules, toxic adenoma, inflammation of the thyroid, eating too much iodine, and too much synthetic thyroid hormone. Diagnosis of this condition can help to relieve the symptoms and prevent long term complications.
Q. What is Hypothyroidism?
Hypothyroidism, also called underactive thyroid or low thyroid is a condition in which the thyroid gland does not produce enough thyroid hormones. It can be commonly caused by intake of low iodine diet or Hashimoto's thyroiditis (an autoimmune disease). Less common causes include previous treatment with radioactive iodine, injury to the pituitary gland which secretes TSH, intake of certain medicines, previous thyroid surgery or a lack of a functioning thyroid gland at birth.
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Provided By

NABL

CAP

At Metropolis, the best pathology lab in India what we believe is what we say and what we say is what we do. Being empathetic to our customers and being committed to their needs is in our DNA. Metropolis has grown to harness a culture that is open, synergistic, progressive and scientific in nature. We are the Pathology Specialists delivering over 30 million tests a year, catering to more than 20,000 medical Laboratories, Hospitals, Nursing homes and 2,00,000 Consultants. With 37 years of experience in delivering accurate reports, Metropolis has earned the reputation of being amongst the top pathology labs in India.
User Reviews
M
Monika
Very Good Experience. I got my reports on the same day.. Thank you 1 MG for Superfast Service !! Keep it Up :-)
G
Gopal
Good Job............Keep it up
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