Zonalta 8mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 07 Apr 2026 | 02:54 PM (IST)

Zonalta 8mg Tablet is a medicine used in the treatment of manic episodes with or without mixed features of bipolar disorder. It works by increasing the level of chemical messengers in the brain which improves mood and symptoms of mania.

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General Information

Storage

Store below 30°C

The content is shown in English

Product introduction

Zonalta 8mg Tablet may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, headache, and insomnia. Zonalta 8mg Tablet is unlikely to impair the ability of patients to drive or operate machinery. However, fatigue has been reported with the use of parent drug and caution should be observed when driving or using machinery while such symptoms persist.

Before taking Zonalta 8mg Tablet, inform your doctor if you are suffering from thyroid or kidney disease, epilepsy, Parkinson’s disease, glaucoma, or any heart disease. You should inform your doctor if you are taking medicines like sleep-inducing, cough, and/or allergy medication.

Up to date, there is no report or observation of change in body weight with use of Zonalta 8mg Tablet. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Zonalta Tablet

Treatment of manic episodes with or without mixed features of Bipolar disorder

Benefits of Zonalta Tablet

Treatment of manic episodes with or without mixed features of Bipolar disorder
Zonalta 8mg Tablet works to restore the normal balance of neuronal activity in your brain. It can help prevent extreme changes in mood mainly elated and help you feel calm. It can take several weeks for this medicine to work and you may still feel high during this time. It is likely that you will take this medicine for at least three weeks. It needs to be taken regularly to work effectively. Do not stop taking it unless your doctor advises you to. You should continue to eat well and keep fit to reduce symptoms of bipolar disorder.

Side effects of Zonalta Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zonalta

Insomnia (difficulty in sleeping)
Headache
Nausea
Indigestion
Decreased appetite
Delusion

How to use Zonalta Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zonalta 8mg Tablet may be taken with or without food.

How Zonalta Tablet works

Zonalta 8mg Tablet directly inhibits protein kinase C activity (which is found increased to be increased in the manic phase of patients with bipolar I disorder) in the nervous system and subsequently helps to manage certain chemicals in the brain such as glutamate, norepinephrine, serotonin, and dopamine that control your mood.

Quick tips

Inform your doctor if you experience chest pain or a fast heartbeat after starting treatment with Zonalta 8mg Tablet.
Avoid breastfeeding during treatment with this medicine and for three months after the last dose.
Zonalta 8mg Tablet might cause menstrual irregularity or amenorrhea. Consult your doctor.
Use contraception to avoid getting pregnant during treatment with this medicine since it may cause fetal harm.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Zonalta 8mg Tablet.

Pregnancy

UNSAFE

Zonalta 8mg Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

UNSAFE

Zonalta 8mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

CONSULT YOUR DOCTOR

It is not known whether Zonalta 8mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Zonalta 8mg Tablet is unlikely to impair the ability to drive or operate machinery. However, fatigue has been reported. Caution should be observed when driving or using machinery while such symptoms persist.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Zonalta 8mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Zonalta 8mg Tablet in patients with liver disease.

Frequently asked questions

What is bipolar disorder?

Bipolar disorder is a mental illness that leads to sudden changes in mood, energy, activity levels, concentration, and the ability to carry out day-to-day tasks. It is typically diagnosed during late adolescence or early adulthood. Bipolar disorder requires lifelong treatment. Following a prescribed treatment routine can help people manage their symptoms and improve their quality of life.

Can I quit taking Zonalta 8mg Tablet on my own if I start feeling better?

It is not advisable to stop taking this medicine even if you begin to feel better, as it may cause recurring symptoms. Therefore, continue taking it for as long as it is prescribed by the doctor.

Does Zonalta 8mg Tablet cause indigestion or diarrhea?

Zonalta 8mg Tablet may cause indigestion or diarrhea. Do not take any medicine to treat this condition without a doctor's notice. It does not require medical attention and will resolve gradually over time in most cases. However, it is advisable to consult your doctor if you experience these side effects persistently.

Is Zonalta 8mg Tablet safe to take during pregnancy and breastfeeding?

This medicine should not be given to women who are pregnant or breastfeeding. A pregnancy test should be performed prior to starting treatment in women with reproductive potential and should be instructed to use effective contraception during the treatment with Zonalta 8mg Tablet.

Can Zonalta 8mg Tablet cause visual disturbances?

Yes, this medicine may cause eye problems, including visual disturbances or more serious retinopathy. Seek medical help if you experience such problems.

Fact Box

Chemical Class

Triphenylethylenes

Habit Forming

Therapeutic Class

NEURO CNS

References

Ahmad A, Sheikh S, Shah T, et al. Endoxifen, a New Treatment Option for Mania: A Double-Blind, Active-Controlled Trial Demonstrates the Antimanic Efficacy of Endoxifen. Clin Transl Sci. 2016;9(5):252-259. [Accessed 24 Nov. 2022] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India

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Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Zonalta 8mg Tablet

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General Information

Contains

Salt Synonyms

Marketer

Storage

Product introduction

Uses of Zonalta Tablet

Benefits of Zonalta Tablet

Side effects of Zonalta Tablet

How to use Zonalta Tablet

How Zonalta Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is bipolar disorder?

Can I quit taking Zonalta 8mg Tablet on my own if I start feeling better?

Does Zonalta 8mg Tablet cause indigestion or diarrhea?

Is Zonalta 8mg Tablet safe to take during pregnancy and breastfeeding?

Can Zonalta 8mg Tablet cause visual disturbances?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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