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Zilo P Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 31 Mar 2026 | 02:32 PM (IST)
Zilo P Tablet is used to treat common cold symptoms. It provides temporary relief from stuffiness in the nose. It also helps relieve allergy symptoms like a runny nose and watery eyes.
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The content is shown in English
Zilo P Tablet image
Zilo P Tablet image

Product introduction

Zilo P Tablet is taken with or without food in a dose and duration as advised by the doctor. It is better to take it with food to avoid stomach upset. The dose you are given will depend on your condition and how you respond to the medicine. You should keep taking this medicine for as long as your doctor recommends. If you stop treatment too early, your symptoms may come back, and your condition may worsen. Let your doctor know about all other medications you are taking, as some may affect or be affected by this medicine.


The most common side effects are nausea, vomiting, stomach pain, insomnia, restlessness, impaired coordination, and headache. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It can also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine, as it can make dizziness worse.


Before taking it, you should tell your doctor if you have any kidney or liver diseases so that your doctor can prescribe a suitable dose for you. Also, tell your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Uses of Zilo P Tablet

Benefits of Zilo P Tablet

Treatment of Common cold
Zilo P Tablet is a combination of medicines that effectively relieves symptoms of common cold such as blocked nose, runny nose, watery eyes, sneezing, and congestion or stuffiness. It helps to loosen thick mucus, making it easier to cough out. This makes it easier for air to move in and out. It shrinks the blood vessels and provides rapid relief that lasts for several hours.

Side effects of Zilo P Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Zilo P
  • Nausea
  • Vomiting
  • Insomnia (difficulty in sleeping)
  • Dizziness
  • Impaired coordination
  • Headache
  • Sedation
  • Impaired concentration
  • Irritability
  • Tremors
  • Diarrhea
  • Dryness in mouth
  • Fatigue
  • Blurred vision

How to use Zilo P Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Zilo P Tablet may be taken with or without food.

How Zilo P Tablet works

Zilo P Tablet is a combination of four medicines: caffeine, diphenhydramine, paracetamol, and phenylephrine, which relieve common cold symptoms. Diphenhydramine is an antiallergic that relieves allergy symptoms like a runny nose, watery eyes, and sneezing. Paracetamol is an analgesic (pain reliever) and an antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that are responsible for pain and fever. Caffeine increases the effectiveness of paracetamol and decreases the sleepiness caused by diphenhydramine. Phenylephrine is a decongestant that narrows the small blood vessels, providing temporary relief from congestion or stuffiness in the nose.

Quick tips

  • Take exactly as directed by your doctor or on the label. Do not increase the dosage or take it for longer than is recommended.
  • Inform your doctor if you are taking any other medications for a cold.
  • Call your doctor if your symptoms have not improved within seven days of treatment or if you develop a fast, pounding, or uneven heartbeat; severe dizziness or anxiety; or a severe headache, fever, or rash.
  • Inform your doctor if you are taking any antidepressants.
  • Along with taking Zilo P Tablet, do the following simple tips at home to get relief, such as steam inhalation and gargling with warm saltwater.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Zilo P Tablet. Please consult your doctor.
Pregnancy

Pregnancy

UNSAFE
Zilo P Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Zilo P Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Zilo P Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Zilo P Tablet should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular monitoring of blood pressure is advised for dose adjustment.
Liver

Liver

UNSAFE
Zilo P Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Zilo P Tablet is a combination of four medicines: paracetamol, caffeine, diphenhydramine, and phenylephrine. This combination helps relieve the symptoms of cold, such as body aches, headache, fatigue, fever, watery eyes, sneezing, cough, sore throat, and runny and stuffy nose.
Zilo P Tablet contains caffeine. Therefore, it is preferable to avoid consuming medicines or foods that contain caffeine. Foods like coffee, tea, cola drinks, or chocolate should be avoided as they may add to your total caffeine intake. Also, avoid drinking alcohol (beer, wine, etc.) while you are taking this medicine.
Yes, Zilo P Tablet can make you feel drowsy or sleepy. Avoid driving a car, operating machinery, working at heights, or participating in potentially dangerous activities at the beginning of your treatment until you know how this medicine affects you.
Serious side effects with Zilo P Tablet are uncommon and rare. Tell your doctor as soon as possible if you notice allergic reactions, skin rash or peeling, mouth ulcers, breathing problems, unexplained bleeding, recurrent fevers or infections, vision disturbances, or a fast or irregular heartbeat.
No, it is not advisable to breastfeed while using Zilo P Tablet. This medicine contains diphenhydramine, an antihistamine, which can pass into breast milk and may harm the baby. Inform your doctor that you are breastfeeding if you are advised to take this medicine.
Yes. Zilo P Tablet should not be used in patients who are allergic to paracetamol, phenylephrine, caffeine, diphenhydramine, or any of its components. It is also contraindicated in people who have taken monoamine oxidase inhibitors (MAOIs) within the last 14 days or those taking other sympathomimetic medicines. Additionally, it should be avoided in patients with cardiovascular disorders, peripheral vascular disease, severe liver or kidney impairment, hyperthyroidism, glaucoma, prostate enlargement, or pheochromocytoma.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, and other people.

Fact Box

Habit Forming

No

Therapeutic Class

RESPIRATORY
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Dr Kumars Pharmaceuticals
Address: SCF 421, Ist Floor, Motor Market, Manimajra Chandigarh-160047,India

Vendor Details

Country of origin: India
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