Zavedos 10mg Capsule is used in the treatment of some kinds of blood cancer (leukemia). It may be also used to treat other conditions, as determined by the doctor. It is sometimes used with certain other medicines as part of combination chemotherapy.

Zavedos 10mg Capsule can be taken with or without food, but try to have it at the same time every day to get most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, nausea, infection, hair loss, and fever. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Zavedos Capsule

Blood cancer (Acute lymphocytic leukemia)

Benefits of Zavedos Capsule

In Blood cancer (Acute lymphocytic leukemia)

Acute lymphocytic leukemia (ALL) is a type of blood cancer where the bone marrow produces too many immature white blood cells, crowding out healthy cells and affecting normal blood function. Zavedos 10mg Capsule helps destroy these cancer cells, reducing their growth and spread, which supports recovery and improves overall treatment outcomes.

Side effects of Zavedos Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Zavedos

Vomiting
Nausea
Infection
Hair loss
Fever
Increased liver enzymes
Peripheral neuropathy (tingling and numbness of feet and hand)
Stomatitis (Inflammation of the mouth)
Bleeding
Myelosuppression
Seizure

How to use Zavedos Capsule

Take this medicine in the dose and duration as advised by your doctor. Zavedos 10mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Zavedos Capsule works

Zavedos 10mg Capsule is an anti-cancer medication. It works by suppressing the activity of an enzyme (topoisomerase II) involved in DNA multiplication of the cancer cells. It also forms harmful chemicals (free radicals) which cause DNA damage. This slows the growth of cancer cells and eventually kills them.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Zavedos 10mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Zavedos 10mg Capsule is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Zavedos 10mg Capsule is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Zavedos 10mg Capsule may cause side effects which could affect your ability to drive.
Special care should be taken if it is essential that you drive while undergoing treatment especially if you are lacking strength or are in a debilitated condition.

Kidney

CAUTION

Zavedos 10mg Capsule should be used with caution in patients with kidney disease. Dose adjustment of Zavedos 10mg Capsule may be needed. Please consult your doctor.
Get kidney function tests done before the start of this medicine.

Liver

CAUTION

Zavedos 10mg Capsule should be used with caution in patients with liver disease. Dose adjustment of Zavedos 10mg Capsule may be needed. Please consult your doctor.
Get liver function tests done before the start of this medicine.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

Zavedos 10mg Capsule should be taken with or without food but at the same time every day.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your blood uric level, liver function, blood cell count in your blood.
Inform your doctor if you experience dizziness, fever, shortness of breath and itchy rash.

Fact Box

Chemical Class

Anthracycline Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Other Anticancer Agents

Interaction with drugs

Taking Zavedos with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Molgramostim (Injection Route) Life-threatening

Do not consume Idarubicin from 1 day before until 1 day after taking Molgramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marro... More

Pegfilgrastim (Injection Route) Life-threatening

Do not consume Idarubicin from 14 days before until 24 days after taking Pegfilgrastim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone ... More

Sargramostim (Injection Route) Life-threatening

Do not consume Idarubicin from 1 day before until 1 day after taking Sargramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marro... More

Lenograstim (Injection Route) Life-threatening

Do not consume Lenograstim from 24 hours before until 24 hours after undergoing cytotoxic chemotherapy. Concurrent use may cause a decrease in the ability of the bone marrow to pr... More

Natalizumab (Injection Route) Life-threatening

Do not consume Natalizumab with Idarubicin. Concomitant use may increase the risk of opportunistic infections.

View all drug interactions

Patient concerns

I want to know about Acute Lymphoblastic Leukemia CNS Relapse protocol followed by standard doctors.

Dr. Vijay Sharnangat

Medical Oncology and Hematology

What you want know

Features suggestive of acute myeloid leukemia Is this disease is curable if no than how much time did the patient have with & without treatment

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

Less chances of cureHowever treatment is possible

I'm detected with acute lymphoblastic leukemia taking alloepathy treatment but finding it costly want to start homeopathy treatment along with it kindly help

Dr. Manju Singh

Homeopathy

I would like to recommend you that if you want to start homeopathy then you should visit a homeopathic physician who is nearer to your home because your case require a detail case taking then your medicine will be selected on the basis of your symptoms.

Is Zavedos 10mg Capsule a vesicant?

Zavedos 10mg Capsule can cause inflammation of the vein in which it is administered; and irritation and ulceration of surrounding tissue, if leakage occurs at the site of intravenous administration.

What is Zavedos 10mg Capsule used for?

Zavedos 10mg Capsule is used in the treatment of acute myeloid leukaemia (a type of cancer of the white blood cells) in combination with other medications and breast cancer in advance stage after failure with other medications.

How does Zavedos 10mg Capsule work?

Zavedos 10mg Capsule acts by inhibiting the growth of cancer cells.

Related lab tests

Complete Blood Count

Peripheral Smear Examination

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 686-87.
Idarubicin. Ramsgate Road Sandwich: Pfizer Limited; 2002 [revised Aug. 2018]. [Accessed 27 Mar. 2019] (online) Available from:
National Cancer Institute. Idarubicin. [Accessed 27 Mar. 2019] (online) Available from: