Xpreza 300mg Tablet

Azacitidine (300mg)

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Xpreza 300mg Tablet is used for the treatment of adult patients with all subtypes of Myelodysplastic Syndrome (MDS). It may also be used to treat other conditions, as determined by the doctor.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 11 Sep 2026 | 01:04 AM (IST)

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14 tablets

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General Information

Contains

Azacitidine (300mg)

Marketer

Natco Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Xpreza 300mg Tablet can be taken with or without food, but better to have it same time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include vomiting, weakness, nausea, and pneumonia. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You must inform your doctor before taking any vaccination while on treatment with this medicine. Regular blood tests are required to check your blood cells along with the heart, liver, and kidneys.

Before taking it, tell your doctor if you have liver or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine, so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding.

Uses of Xpreza Tablet

Treatment of Myelodysplastic syndrome

Benefits of Xpreza Tablet

Treatment of Myelodysplastic syndrome
Xpreza 300mg Tablet is used to treat myelodysplastic syndrome, a group of conditions in which the bone marrow produces blood cells that are abnormal in structure and function, and does not produce enough healthy blood cells. Xpreza 300mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells.

Side effects of Xpreza Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xpreza

Vomiting
Weakness
Nausea
Upper respiratory tract infection
Joint pain
Decreased appetite
Pain in extremities

How to use Xpreza Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Xpreza 300mg Tablet may be taken with or without food.

How Xpreza Tablet works

Xpreza 300mg Tablet is an anticancer medication. It works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells in leukaemia. This kills the cancer cells and helps in normal maturation and growth of young blood cells in the bone marrow.

All substitutes for Xpreza 300mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.
Women who can become pregnant should use effective contraception during treatment and for at least 6 months after the last dose. Men with female partners who can become pregnant should use effective contraception during treatment and for at least 3 months after the last dose.
Do not breastfeed while taking Xpreza 300mg Tablet and for 1 week after the last dose. Tell your doctor if you have kidney or liver problems or are taking any prescription medicines, OTC medicines, vitamins, or herbal supplements.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Xpreza 300mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Xpreza 300mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

UNSAFE

Xpreza 300mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Xpreza 300mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Xpreza 300mg Tablet can cause side effects such as tiredness and this may affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Xpreza 300mg Tablet in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Xpreza 300mg Tablet in patients with liver disease.

Frequently asked questions

Is Xpreza 300mg Tablet a vesicant?

Xpreza 300mg Tablet is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Xpreza 300mg Tablet into the surrounding tissues from the site of administration) when injected

Does Xpreza 300mg Tablet cause hair loss?

No, Xpreza 300mg Tablet is not known to cause hair los

Is Xpreza 300mg Tablet chemotherapy?

Yes. Xpreza 300mg Tablet is chemotherapy and a cytotoxic drug used in the treatment of various cancers. It is toxic to cancer cells and interferes with the cell's DNA synthesis, thus slowing down or stopping its growth and multiplication (cytotoxic effect)

Is Xpreza 300mg Tablet a cytotoxic drug?

Yes. Xpreza 300mg Tablet is a cytotoxic drug.

Why are regular blood tests needed during treatment?

Xpreza 300mg Tablet can lower white blood cells and platelets, which may increase the risk of infection and bleeding. Your doctor will therefore monitor your blood counts before and during treatment and may adjust treatment if necessary.

Can Xpreza 300mg Tablet affect fertility?

Yes. Xpreza 300mg Tablet may cause fertility problems in both men and women, which could affect the ability to have children. Discuss fertility concerns with your doctor before or during treatment.

Fact Box

Chemical Class

Glycosylamines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Antimetabolites

Related lab tests

Bone Marrow Smear Microscopy Examination

Complete Blood Count

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1700.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 112-13.
Azacitidine. Princeton, NJ: Bristol-Myers Squibb Company; 2026. [Accessed 10/09/2026] (online). Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Xpreza 300mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Home

Anti Neoplastics

Antimetabolites

Xpreza 300mg Tablet

Xpreza 300mg Tablet

Payment, Returns & Expiry

Online payment only

We don’t take this product back

Product expires after Dec, 2026

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Xpreza Tablet

Benefits of Xpreza Tablet

Side effects of Xpreza Tablet

How to use Xpreza Tablet

How Xpreza Tablet works

All substitutes for Xpreza 300mg Tablet

BD-Zadine 300 Tablet

Azadine-O Tablet

AZAshine 300mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Xpreza 300mg Tablet a vesicant?

Does Xpreza 300mg Tablet cause hair loss?

Is Xpreza 300mg Tablet chemotherapy?

Is Xpreza 300mg Tablet a cytotoxic drug?

Why are regular blood tests needed during treatment?

Can Xpreza 300mg Tablet affect fertility?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Bone Marrow Smear Microscopy Examination

Complete Blood Count

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests