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Introduction of Chlorpheniramine Maleate

Xosal Cold Syrup is used in the treatment of common cold symptoms like runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness. It also helps in relieving pain and fever.

This medication may be taken with or without food preferably one hour before you travel. Take it in a dose and duration as advised by the doctor. But, before taking it, inform doctor if you are suffering from depression and taking its medicines.

Dizziness may occur as its side effect, so do not drive or do anything that requires mental focus. You should avoid drinking alcohol while taking this medicine, as it may cause excessive sleepiness.

Introduction of Dextromethorphan Hydrobromide

Xosal Cold Syrup is used in the treatment of common cold symptoms like runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness. It also helps in relieving pain and fever.

This medicine is taken by mouth with or without food. You should take it in a proper dose and duration as advised by the doctor. Remember dosage is decided on the basis of type of medicine (syrup or lozenge), age and present medical condition of the person. It is important to finish the full course of treatment even if you feel better. In case you have missed any dose, take it as soon as you remember it. Its beneficial to have plenty of fluids while taking this medication.

It is important to note that you should never support self medication or recommend your medicine to other person. Keep out of reach of children as overdose of this medicine can be dangerous. This medicine may cause dizziness as a side effect, so do not drive or do anything that requires mental focus. Rashes and diarrhea may also occur in many individuals.

Introduction of Paracetamol

Xosal Cold Syrup is used in the treatment of common cold symptoms like runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness. It also helps in relieving pain and fever.

Xosal Cold Syrup may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor. It is usually best taken with food otherwise it may upset your stomach. Do not take more or use it for longer than recommended.

Side effects are rare if this medicine is used correctly but this medicine may cause stomach pain, nausea, and vomiting in some people. Consult your doctor if any of these side effects bother you or do not go away.

This medicine is widely prescribed and considered safe but is not suitable for everybody. Before taking it, let your doctor know if you have liver or kidney problems or are using blood-thinning medicines. It may affect the dose or suitability of this medicine. Let your doctor know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

Introduction of Phenylephrine

Xosal Cold Syrup is used in the treatment of common cold symptoms like runny nose, stuffy nose, sneezing, watery eyes and congestion or stuffiness. It also helps in relieving pain and fever.

Xosal Cold Syrup is best taken with food. Use it in the dose and duration as prescribed by your doctor. This medicine needs to be taken regularly to get the most benefit from it. Keep using it as prescribed even if your symptoms disappear. Before you take this medicine, let your doctor know about any other medicines you are taking. You should also tell your doctor if you have any problems with your heart, liver, or kidneys.

The most common side effects of taking this medicine include irregular heart beats, high blood pressure, nausea, vomiting, and headache. While you are on treatment with this medicine, do not smoke as it can worsen your symptoms. Drinking alcohol can also effect how the medicine works and should be avoided. It is not recommended for pregnant women, however it may be safe for breastfeeding mothers if the doctor's prescribes it.

Uses of Chlorpheniramine Maleate

Uses of Dextromethorphan Hydrobromide

Uses of Phenylephrine

Benefits of Dextromethorphan Hydrobromide

In Dry cough

A dry cough, also known as non-productive cough, is a cough where no phlegm or mucus is produced. This is irritating, usually associated with a tickly throat and may be caused due to cold, flu, allergies or throat irritants. Xosal Cold Syrup suppresses dry, hacking coughs. It will help you carry out your daily activities more easily.

This medicine is safe and effective. Xosal Cold Syrup usually starts to work within a few minutes and the effects can last up to several hours. Take it as prescribed by the doctor. Do not stop using it unless you are advised to by your doctor.

Benefits of Paracetamol

In Pain relief

Xosal Cold Syrup is a common painkiller used to treat aches and pains. It works by blocking chemical messengers in the brain that tell us we have pain. It is effective in relieving pain caused by headache, migraine, nerve pain, toothache, sore throat, period (menstrual) pains, arthritis, and muscle aches. This medicine is very widely used and very rarely causes side effects if taken at the right dosage. Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. It is also the first choice of painkiller during pregnancy or breastfeeding.

In Treatment of Fever

Xosal Cold Syrup is also used to reduce a high temperature (fever). It works by blocking the release of certain chemical messengers that cause fever. It may be prescribed alone or in combination with another medicine. You should take it regularly as advised by your doctor.

Side effects of Chlorpheniramine Maleate

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xosal Cold

  • Dryness in mouth
  • Sleepiness
  • Drowsiness
  • Loss of appetite
  • Nausea

Side effects of Dextromethorphan Hydrobromide

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xosal Cold

  • Sleepiness
  • Dizziness
  • Excitement
  • Confusion
  • Convulsion
  • Respiratory depression
  • Nausea
  • Vomiting
  • Diarrhea
  • Rash

Side effects of Paracetamol

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Xosal Cold

  • Nausea
  • Vomiting
  • Insomnia (difficulty in sleeping)
  • Headache
  • Constipation
  • Itching

Side effects of Phenylephrine

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Serve side effects of Xosal Cold

  • Nausea
  • Vomiting
  • Headache
  • High blood pressure
  • Arrhythmia (irregular heartbeats)
  • Blurred vision
  • Breathlessness
  • Itching
  • Restlessness
  • Reflex bradycardia
  • Excitation
  • Epigastric pain
  • Neck pain
  • Tremors
  • Hypertensive crisis
  • Eye pain
  • Stinging in the eyes
  • Photophobia
  • Conjunctival sensitivity
  • Preterm and low birth weight infants
  • Fainting
  • Myocardial infarction
  • Subarachnoid hemorrhage

How Chlorpheniramine Maleate works

Xosal Cold Syrup is an antiallergic medication. When your body is exposed to an allergen (pollen, animal dander, house dust etc.), it produces a chemical called histamine. This causes watery eyes, runny or blocked nose, sneezing, skin rashes, itching etc. Xosal Cold Syrup works by blocking the action of histamine, thereby relieving these symptoms.

How Dextromethorphan Hydrobromide works

Xosal Cold Syrup is an antitussive (cough suppressants). It suppresses cough by reducing the activity of cough centre in the brain.

How Paracetamol works

Xosal Cold Syrup is an analgesic (pain reliever) and anti-pyretic (fever reducer). It works by blocking the release of certain chemical messengers that cause pain and fever.

How Phenylephrine works

Xosal Cold Syrup is a decongestant. It works by narrowing the small blood vessels which provides temporary relief from inflammation (redness and swelling) and discomfort.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Xosal Cold Syrup.
Pregnancy
CONSULT YOUR DOCTOR
Xosal Cold Syrup may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Xosal Cold Syrup is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
UNSAFE
Xosal Cold Syrup may cause side effects which could affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Xosal Cold Syrup is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Xosal Cold Syrup may not be needed in these patients. Please consult your doctor.
Liver
UNSAFE
Xosal Cold Syrup is probably unsafe to use in patients with liver disease and should be avoided. Please consult your doctor.

What if you forget to take Xosal Cold Syrup?

If you miss a dose of Xosal Cold Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
Xosal Cold Syrup
₹49.95/Syrup
Trixil Syrup
Divine Lifecare Pvt Ltd
₹42/syrup
16% cheaper
Zycold Syrup
Zodak Healthcare
₹46/syrup
8% cheaper
Tacof P Syrup
Biostrass Health Sciences Pvt Ltd
₹55/syrup
10% costlier
Coldsin P Syrup
Assure Pharma
₹55/syrup
10% costlier
Goodex P Syrup
Vervetic Healthcare Pvt Ltd
₹68.95/syrup
38% costlier

Quick tips

Chlorpheniramine Maleate

  • Avoid driving or operating dangerous machinery as it may decrease alertness.
  • Avoid consuming alcohol when taking the Chlorpheniramine Maleate, as it may cause excessive sleepiness or drowsiness.

Dextromethorphan Hydrobromide

  • You have been prescribed Dextromethorphan Hydrobromide for the symptomatic relief of dry cough.
  • It is usually taken for a short time, until the symptoms clear up.
  • Allow the lozenge or disintegrating strip to dissolve in your mouth. Do not chew or swallow.
  • Measure the syrup with a special dose-measuring spoon or cup, not a regular table spoon. 
  • Drink extra fluids to help loosen the congestion and lubricate your throat while you are taking this medication.
  • It should not be administered to patients with chronic cough or where cough is accompanied by excessive secretions.
  • Inform your doctor if your cough lasts more than 7 days, comes back, or occurs with fever, rash or headache. These could be signs of a serious condition.

Paracetamol

  • Paracetamol should be taken with food or milk to prevent upset stomach.
  • Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious complications such as stomach bleeding and kidney problems.
  • Do not take indigestion remedies (antacids) within 2 hours of taking Paracetamol.
  • Avoid consuming alcohol while taking this medicine as it can increase your risk of stomach problems.
  • Inform your doctor if you have liver disease as your dose may need to be adjusted.
  • Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long-term treatment.

Phenylephrine

  • Oral phenylephrine should be taken with food
  • Phenylephrine can make you restless, so don't take it too close to bedtime
  • Do not use this medicine without doctor's advice if you are pregnant or breast feeding
  • Smoking may worsen the effect; therefore use of tobacco should be avoided.

Fact Box

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Therapeutic Class
RESPIRATORY

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FAQs

Chlorpheniramine Maleate

Q. Does chlorpheniramine or chlorpheniramine maleate cause increase in blood pressure/ drowsy/non drowsy/sedating/get you high/keep you awake/sleepiness/make you tired/weight gain?

Chlorpheniramine causing these side effects is common or rare. Always consult your doctor, if you experience any of these side effects

Q. Is chlorpheniramine like Benadryl?

No, chlorpheniramine is different from Benadryl

Q. Is chlorpheniramine prescription?

Yes, it is available with doctor’s prescription only

Q. Can I take chlorpheniramine or chlorpheniramine maleate with Panadol/ cetirizine /Zyrtec/ Allegra/ warfarin/ diphenhydramine/ ibuprofen/Claritin/guaifenesin/Benadryl?

Yes, but taking other medicines may alter the effects of chlorpheniramine. Always consult your doctor for the change of dose regimen or an alternative drug of choice that may strictly be required

Q. Does chlorpheniramine contain aspirin?

No, it does not contain aspirin in it. Chlorpheniramine is a different drug than aspirin.
Dextromethorphan Hydrobromide

Q. Is dextromethorphan a steroid/an opiate/an antihistamine/ a narcotic/an NSAID/a controlled substance/contain alcohol/have codeine?

Dextromethorphan is a decongestant and not a steroid, antihistamine, opiate, NSAID or narcotic, but can have addictive effects if taken at large doses than recommended. It does not contain codeine or alcohol. It is not a controlled substance

Q. Does dextromethorphan work/ how much dextromethorphan can I take for cough?

Dextromethorphan works for most of the patient. It should be taken in amounts exactly as directed on the label, or as prescribed by your doctor. Cough medicine is usually taken only for a short time until your symptoms clear up. Do not use the medication in larger amounts, or use it for longer than recommended

Q. Is dextromethorphan safe/ does dextromethorphan makes you sleepy/make you tired/ raise blood sugar?

Dextromethorphan causes mild sedation effect thus can make you feel sleepy. It does not raise blood sugar or make you tired. Dextromethorphan is generally safe if taken at recommended doses and duration

Q. Can i take dextromethorphan with high blood pressure/ safe for high blood pressure/ raise blood pressure/ thin blood?

Though it isn't reported, but it should be used carefully in people with high blood pressure, as dextromethorphan may cause high blood pressure and the effectiveness of dextromethorphan is decreased by high blood pressure medications

Q. Can I take dextromethorphan with benzonatate/acetaminophen/codeine/ibuprofen/ diphenhydramine/pseudoephedrine/guaifenesin/Tamiflu/Benadryl?

Drug interaction with any of the above mentioned drugs is not documented, but it can occur. Always follow your doctor's advice before taking any medicine with dextromethorphan.
Paracetamol

Q. What if I vomit after taking Paracetamol?

If you vomit in less than 30 minutes after having a dose of Paracetamol tablets or syrup, retake the same dose again. If you vomit after 30 minutes of a dose, you do not need to take another one until the next standard dose.

Q. When will I feel better after taking the Paracetamol?

Usually, you will start feeling better after about half an hour of taking a Paracetamol.

Q. How often can I take the Paracetamol?

You should only take four doses of Paracetamol in 24 hours. There should be a gap of at least 4 hours between two doses. Do not take Paracetamol for more than 3 days without consulting a doctor first.

Q. Does Paracetamol make babies sleepy?

No, Paracetamol does not make babies sleepy. It is a pain-relieving medicine that is also used to control high fever.

Q. Is Paracetamol safe for children?

Paracetamol is considered safe for children only when used as directed by the doctor.

Q. Is Paracetamol an antibiotic?

No, Paracetamol is not an antibiotic. It works as a painkiller and fever-reducing medicine.

Q. Can I take Paracetamol and ibuprofen together?

Ibuprofen and Paracetamol are safe medicines, but both should not be used together. Consult your doctor if you are not sure.

Q. How long does a Paracetamol take to work?

Paracetamol takes around 30-45 min to start working and show its effects. It is advised to take this medicine for the duration suggested by the doctor. Consult your doctor if you experience any bothersome side effects.

Q. What are the serious side effects of taking an excess of the Paracetamol?

Overdose of Paracetamole may cause severe life-threatening liver injury. Taking more than the prescribed dose may also cause kidney injury, decreased platelet count, and even coma. Early symptoms of an overdose include nausea, vomiting, and general tiredness. Immediately consult a doctor or reach an emergency in case of a suspected overdose.
Phenylephrine

Q. Is it safe to use Phenylephrine?

Yes, Phenylephrine is safe for most of the patients. However, in some patients, it may cause side effects like nausea, vomiting, headache, fatigue, dizziness, dryness in the mouth, sleepiness and allergic reaction. If you experience any persistent problem while taking this medication, inform your doctor as soon as possible.

Q. Can the use of Phenylephrine cause dizziness?

Yes, the use of Phenylephrine can cause dizziness (feeling faint, weak, unsteady or lightheaded) in some patients. If you feel dizzy or lightheaded, it is better to rest for sometime and resume once you feel better. Do not drive or use any machines. Consult your doctor if the side effect persist or worsen.

Q. Can the use of Phenylephrine cause nausea and vomiting?

Yes, the use of Phenylephrine can cause nausea and vomiting. To avoid nausea one can take Phenylephrine with milk, food or with antacids. If vomiting occurs, drink plenty of water or other fluids. Talk to your doctor if vomiting persists. You should let your doctor know if you are unable to drink water and there are signs of dehydration, like dark colored and strong-smelling urine and a low frequency of urination. Avoid taking fatty or fried foods along with this medication. Do not take any other medicine without consulting your doctor.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan HBr, Phenylephrine HCl. Lumberton, New Jersey: AAA Pharmaceutical, Inc. [Accessed 18 Apr. 2019] (online) Available from:External Link

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