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Varcolate-Neo Injection 1
Varcolate-Neo Injection 2
Genuine
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required
Varcolate-Neo Injection is a combination medicine that is used during anesthesia while performing various medical procedures.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 17 Sep 2026 | 01:06 AM (IST)
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5 ml Injection
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Product expires after Dec, 2026

Expiry date may vary by batch. All batches have a 3-month shelf life from the date of dispatch.

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General Information

Contains

Glycopyrrolate (0.5mg)+ Neostigmine (2.5mg)

Marketer

Varenyam Healthcare Pvt Ltd

Storage

Store below 30°C
The content is shown in English
Varcolate-Neo Injection 1
Varcolate-Neo Injection 2

Product introduction

Varcolate-Neo Injection is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. Let your healthcare team know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effect is allergic reaction. This is temporary and usually resolves with time. Contact your doctor straight away if you are at all concerned about these side effects. It may also cause dizziness and sleepiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your dizziness.

Before taking this medicine, you should tell your doctor if you are pregnant, planning pregnancy or breastfeeding. You should also tell your doctor if you have any kidney, stomach or liver diseases so that your doctor can prescribe a suitable dose for you.

Uses of Varcolate-Neo Injection

  • Reversing the effects of certain drugs used during surgery

Benefits of Varcolate-Neo Injection

Reversing the effects of certain drugs used during surgery
Varcolate-Neo Injection is given to reverse the effects of some of the drugs that were used during surgery such as anesthetics and skeletal muscle relaxants. It is given in a hospital setting by a doctor or nurse and should never be self-administered.

Side effects of Varcolate-Neo Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Varcolate-Neo
  • Allergic reaction

How to use Varcolate-Neo Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Varcolate-Neo Injection works

Varcolate-Neo Injection is a combination of two medicines: Glycopyrrolate and Neostigmine.

All substitutes for Varcolate-Neo Injection

For information purposes only. Consult a doctor before taking any medicine.

Myo Pyrolate Injection

by Neon Laboratories Ltd
₹115.97/injection
33% costlier
<h3 class=bodySemiBold>Myo Pyrolate Injection</h3>

Neotagmin P Injection

by Themis Medicare Ltd
₹79.5/injection
9% cheaper
<h3 class=bodySemiBold>Neotagmin P Injection</h3>

Pyrodroid-Neo Injection

by Meddroid Pharmaceuticals Pvt Ltd
₹105/injection
20% costlier
<h3 class=bodySemiBold>Pyrodroid-Neo Injection</h3>

Quick tips

  • Talk to your doctor or nurse before you are given Varcolate-Neo Injection:
    1. If you suffer from asthma attacks, wheezing, or difficulty in breathing
    2. If you have low or high blood pressure
    3. If you suffer from cardiac arrhythmia (irregular heartbeats) or slow heart rate
    4. If you have a history of coronary artery disease or a heart attack.
    5. If you are suffering from epilepsy or Parkinsonism (a disorder in the brain causing muscle stiffness and shaking)
    6. If you suffer from myasthenia gravis (a disease resulting in severe muscle weakness and fatigue)
    7. If you suffer from stomach ulcers
    8. If you suffer from obstruction of the stomach (pyloric stenosis) or bowel causing vomiting, abdominal pain, and swelling (paralytic ileus)
    9. If you are pregnant or breastfeeding.
  • Varcolate-Neo Injection should be used with caution in elderly people.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Varcolate-Neo Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Varcolate-Neo Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Varcolate-Neo Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Long-term use of Varcolate-Neo Injection might reduce milk production.
Driving

Driving

UNSAFE
Varcolate-Neo Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Varcolate-Neo Injection may affect vision and coordination. This may affect your driving ability.
Kidney

Kidney

CAUTION
Varcolate-Neo Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function test and some blood tests may advised while you are taking this medicine.
Liver

Liver

CONSULT YOUR DOCTOR
There is limited data available on the use of Varcolate-Neo Injection in patients with liver disease.
All

Frequently asked questions

Varcolate-Neo Injection is usually given at the end of certain surgical procedures to reverse the effects of medicines that temporarily relax the muscles during anesthesia. This helps restore normal muscle movement, improves breathing strength, and allows the body to recover more smoothly after surgery.
Varcolate-Neo Injection contains two medicines that work together. Neostigmine helps restore muscle function by reversing the effects of muscle-relaxing medicines used during surgery. Glycopyrrolate helps reduce unwanted effects of Neostigmine, such as excessive saliva production and a slow heart rate. Together, they help support a safer recovery from the effcets of anesthesia.
During many operations, muscle-relaxing medicines are used to make surgery easier and safer. However, these medicines can continue affecting the muscles even after the procedure is over. Varcolate-Neo Injection helps reverse these effects so that you can breathe, swallow, and move your muscles normally again.
Varcolate-Neo Injection usually starts working within a few minutes after administration. Many individuals begin to regain muscle strength soon after receiving it. Your anesthesiologist will carefully monitor your recovery to ensure the effects of the muscle relaxant have been adequately reversed.
Your medical team will monitor your breathing, oxygen levels, muscle strength, and ability to move certain muscles. They may ask you to perform simple movements or assess your breathing pattern to confirm that normal muscle function is returning.
It is common to feel tired or weak for some time after surgery. While Varcolate-Neo Injection helps reverse muscle relaxation caused by anesthesia, other factors such as the surgery itself, anesthesia medicines, pain medicines, and lack of sleep can also contribute to temporary weakness.
Dry mouth is a common effect of Glycopyrrolate. This medicine reduces saliva production to counter some of the effects of Neostigmine. The dryness is usually temporary and improves as the medicine wears off. Once permitted by your doctor, drinking fluids may help relieve the discomfort.
Yes. Both the anesthesia process and the medicines used during recovery can influence heart rate. Glycopyrrolate is included to help prevent the slowing of the heart rate that may occur with Neostigmine. Your heart rate will be closely monitored while you recover.
Some individuals may experience nausea, vomiting, stomach cramps, or mild digestive discomfort after receiving Varcolate-Neo Injection. However, these symptoms can also occur as part of the normal recovery process after surgery and anesthesia. Inform your doctor if the symptoms become severe or persistent.
Some individuals may notice sweating, warmth, or flushing after receiving medicines used during anesthesia recovery. These effects are usually temporary and often improve as your body recovers from both the surgery and the anesthesia.
Glycopyrrolate in Varcolate-Neo Injection may occasionally cause temporary vision changes such as blurred vision or increased sensitivity to bright light. These effects are usually short-lived. If vision problems are severe or do not improve, inform your doctor promptly.
No. Varcolate-Neo Injection is used in controlled medical settings such as operating rooms and recovery areas. It requires monitoring by trained healthcare professionals to ensure that muscle function, breathing, and heart rate return to normal safely.
Tell your doctor immediately if you experience severe breathing difficulties, persistent muscle weakness, chest pain, a very fast or irregular heartbeat, severe dizziness, or signs of an allergic reaction such as swelling of the face, lips, or throat. These symptoms require prompt medical attention.
Most individuals gradually regain normal muscle strength and breathing ability as the effects of anesthesia wear off. You may continue to feel sleepy, tired, or slightly weak for several hours after surgery. Your healthcare team will monitor you closely and ensure that recovery is progressing safely before discharge from the recovery area.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Glycopyrronium bromide/neostigmine metilsulfate. London, UK: ADVANZ Pharma; 1998 [revised 16 Mar. 2018]. [Accessed 15 Apr. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Varenyam Healthcare Pvt Ltd
Address: 2, Vitrag Appartment, Karelibaug, Vadodara-390018, Gujarat, INDIA

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Varcolate-Neo Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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