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MRP: Rs. 64.88 for 1 vial(s) (5 ML injection each)
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Composition for MYO PYROLATE

Glycopyrrolate(0.5 mg),Neostigmine(2.5 mg)

food interaction for MYO PYROLATE

alcohol interaction for MYO PYROLATE

pregnancy interaction for MYO PYROLATE

lactation interaction for MYO PYROLATE

There is no data available. Please consult doctor before consuming the drug.
Myo pyrolate injection may cause excessive drowsiness and calmness with alcohol.
Myo pyrolate injection may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Unknown. Human and animal studies are not available. Please consult your doctor.


Glycopyrrolate(0.5 mg)


Glycopyrrolate is used before surgery to reduce secretions of saliva in mouth, throat and airways, acid in stomach; to reduce side effects of muscle-relaxing drugs and to prevent of slowing of heart beat during surgery. It is also used to reduce the drooling of saliva in patients (3-16 years of age) with cerebral palsy (a permanent movement disorder occurring in early childhood).

How it works

Glycopyrrolate belongs to a class of medications called anticholinergics. It decreases the secretions in the mouth, throat, airways and stomach acid.

Common side effects

Nervousness, Loss of sense of taste, Confusion, Constipation, Diarrhoea, Dizziness, Weakness, Drowsiness, Dry mouth, Difficulty in swalloing, Shortness of breath, Difficulty in urination, Abdominal bloating, Headache, Reduced sweating, Insomnia, Stomach upset, Vision disorder, Vomiting
Neostigmine(2.5 mg)


Neostigmine is used to treat symptoms of myasthenia gravis (neuromuscular disease characterized by very weak muscles and unusual tiredness). It is also used in paralytic Ileus (obstruction of the intestine due to paralysis of the intestinal muscles), post-operative urinary retention (difficulty urinating) and paroxysmal supraventricular tachycardia (episodes of rapid heart rate that start in a part of the heart above the ventricles).

How it works

Neostigmine belongs to a class of drugs called cholinesterase inhibitors. It works by improving the transmission of nerve impulses in muscles so that the muscles are able to work better.

Common side effects

Vomiting, Nausea, Frequent urge to urinate, Abnormal heart rhythm, Cough, Flatulence, Headache, Increased saliva production, Decreased blood pressure, Muscle weakness, Thickened respiratory tract secretions, Tingling sensation, Warm sensation, Worsening myasthenia gravis


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Expert advice for MYO PYROLATE

  • Inform your doctor if you have any heart disease, heart failure, irregular heartbeats or high blood pressure as glycopyrrolate is known to increase the heart rate (tachycardia).
  • Glycopyrrolate should be used with caution if you have medical conditions such as myasthenia gravis (progressive neuromuscular disease characterized by weak muscles and unusual tiredness), glaucoma (increased pressure in the eye that causes vision problem), overactive thyroid gland, enlarged prostate gland, obstruction of the stomach or bowel causing vomiting  abdominal pain, chronic constipation and swelling.
  • Glycopyrrolate should be used with special precautions in case of fever as it may worsen the condition.
  • Avoid alcohol or any medication that may cause drowsiness. 
  • Tell your doctor if you are or planning to become pregnant or are breastfeeding.
  • Do not take if allergic to glycopyrrolate or any of its ingredients.

Frequently asked questions for MYO PYROLATE


Q. Is glycopyrrolate used for excessive sweating?
Glycopyrrolate is the most commonly used medicine for managing excessive sweating due to its anti-secretory or anticholinergic effect. 
Q. Is glycopyrrolate the same as glycopyrronium bromide?
Yes, glycopyrrolate is same as glycopyrronium bromide.
Q. Does glycopyrrolate affect fertility & birth control?
No, glycopyrrolate is not known to impair fertility and has no known effects on birth control.
Q. Is glycopyrrolate over the counter?
No, glycopyrrolate is strictly prescribed by the doctors.


Q. Is neostigmine an anticholinesterase/ anticholinergic/agonist/ cholinesterase inhibitor/ neurotransmitter?
Neostigmine is an anticholinesterase. But, it is not an anticholinergic, agonist, cholinesterase inhibitor or a neurotransmitter.
Q. Does neostigmine cause nausea?
Yes, neostigmine causes mild nausea.
Q. Does neostigmine reverse rocuronium/ reverse succinylcholine / inhibit pseudocholinesterase / cause histamine release?
Yes, Neostigmine causes reversal of rocuronium/ succinyl choline and inhibits pseudocholinesterease. It also causes histamine release.


Content on this page was last updated on 13 September, 2016, by Dr. Varun Gupta (MD Pharmacology)