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Valep Chrono Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 18 Jan 2026 | 08:31 PM (IST)
Valep Chrono Tablet is a combination of two medicines used to treat epilepsy, a neurological disorder in which there are recurrent episodes of seizures or fits. It controls the abnormal activity of the brain, relaxes the nerves, and hence, prevents seizures or fits.
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General Information

Contains

Sodium Valproate (300mg)+ Valproic Acid (NA)

Marketer

Abbott

Storage

Store below 30°C
The content is shown in English
Valep Chrono Tablet image
Valep Chrono Tablet image

Product introduction

Valep Chrono Tablet should be taken with food. Your doctor will decide the correct dose for you. This may increase gradually until your condition is stable. This medicine may take several weeks to work, but it is important to take it regularly to get the benefit. Do not stop taking it, even if you feel fine, unless your doctor advises you to. You may have more seizures, or your bipolar disorder may get worse.

The most common side effects of this medicine are nausea and tremor. In some people, it may also cause other side effects like vomiting, headache, liver injury, and upper abdominal pain. Most side effects wear off, but if they bother you or do not go away, tell your doctor. There may be ways of preventing or reducing these effects.

Before taking this medicine, tell your doctor if you have kidney or liver problems, meningitis or depression, or suicidal thoughts. Also, let your doctor know about all other medications you are using, as some may affect, or be affected by, this medicine, including contraceptive pills. If you are pregnant or breastfeeding, Valep Chrono Tablet can be taken if it is clearly needed, but the dose may be adjusted. You should avoid driving or riding a bicycle if this medicine makes you drowsy or dizzy. You may need frequent blood tests to check how you are responding to this medicine.

You should avoid alcohol while taking Valep Chrono Tablet, as it may worsen certain side effects. This medicine can also lead to weight gain. Eat a healthy, balanced diet, avoid snacking with high-calorie food, and exercise regularly. Inform your doctor if you develop any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts or behavior.

Uses of Valep Chrono Tablet

Benefits of Valep Chrono Tablet

Treatment of Epilepsy
Valep Chrono Tablet is an effective anti-epileptic medicine used to control a wide range of seizure types, including absence seizures, myoclonic seizures, and generalized tonic-clonic (grand mal) seizures. It helps stabilize abnormal electrical activity in the brain, reducing the frequency and severity of seizures and supporting better long-term seizure control. When used regularly under medical supervision, they can improve daily functioning and quality of life for people living with epilepsy.

Side effects of Valep Chrono Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Valep Chrono
  • Nausea
  • Tremors

How to use Valep Chrono Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Valep Chrono Tablet should be taken with or after food.

How Valep Chrono Tablet works

Valep Chrono Tablet works by stabilizing electrical activity in the brain. They increase the levels of gamma-aminobutyric acid (GABA), a natural chemical that helps calm nerve activity, and reduce excessive firing of brain cells. This combined action helps prevent the abnormal electrical signals that lead to seizures and supports effective seizure control in epilepsy.

Quick tips

  • Take it at the same time every day to maintain consistent levels in your body.
  • Do not drive or do anything that requires mental focus until you know how Valep Chrono Tablet affects you.
  • Avoid consuming alcohol when taking Valep Chrono Tablet, as it may cause excessive sleepiness or drowsiness.
  • Monitor your weight during the treatment as Valep Chrono Tablet can cause weight gain.
  • Your doctor may monitor the level of medicine in your body, your blood counts, and liver function regularly throughout your treatment. Inform your doctor if you develop fever, stomach pain, nausea, or yellowing of your eyes or skin.
  • Do not take Valep Chrono Tablet if you are pregnant or planning to conceive or breastfeeding.
  • Do not stop taking the medication suddenly without talking to your doctor, as it may increase the seizure frequency.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Valep Chrono Tablet
Pregnancy

Pregnancy

UNSAFE
Valep Chrono Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Valep Chrono Tablet may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving

Driving

UNSAFE
Valep Chrono Tablet may cause side effects that could affect your ability to drive.
Kidney

Kidney

CAUTION
Valep Chrono Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Valep Chrono Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Yes, Valep Chrono Tablet may make you feel drowsy or sleepy. Avoid driving, operating machinery, working at heights, or participating in potentially dangerous activities. Inform your doctor if you experience such an episode while taking this medicine.
No, Valep Chrono Tablet should be continued as advised by the doctor. Stopping Valep Chrono Tablet suddenly may cause the symptoms to reappear, that too with increased frequency. If any problems are experienced due to Valep Chrono Tablet, consult the doctor for re-evaluation.
No, Valep Chrono Tablet should be continued as advised by the doctor. Stopping Valep Chrono Tablet suddenly may cause the symptoms to reappear that too with increased frequency. If any problems are experienced due to Valep Chrono Tablet, consult the doctor for re-evaluation.
No, taking a higher dose than the recommended dose may not be more effective; it may increase the chances of having serious side effects and toxicity. If the recommended doses do not relieve your symptoms or if there is an increased severity of your symptoms, please consult your doctor.
Keep this medicine in the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children, or other people.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS

References

  1. Linde M, Mulleners WM, Chronicle EP, et al. Valproate (valproic acid or sodium valproate or a combination of the two) for the prophylaxis of episodic migraine in adults. Cochrane Database Syst Rev. 2013;(6):CD010611. [Accessed 23 Apr. 2019] (online) Available from:
  2. Sodium Valproate and Valproic Acid [Package Information]. Gangtok, Sikkim: Torrent Pharmaceuticals Ltd.; 2022. [Accessed 17 Jan. 2026] (online) Available from:
  3. National Health Service: Valproate medicines for all patients (male or female) for all indications. 2026. [Accessed 17 Jan. 2026] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India

Lab tests offered by us

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