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MDS (Oral Pathology & Microbiology), BDS
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Last updated:
01 Mar 2021 | 11:16 AM (IST)

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Uromitexan Infusion

Prescription Required
Manufacturer
SALT COMPOSITION
Storage
Store at room temperature (10-30°C)

Introduction

Uromitexan Infusion is used to prevent ifosfamide-induced hemorrhagic cystitis (bleeding in the bladder that may be caused as a side effect due to treatment with a cancer chemotherapy drug called ifosfamide). However, it is not used to reduce the risk of bladder bleeding due to other medical conditions.

Uromitexan Infusion is given under the supervision of a doctor. The dose and duration of the treatment vary on the basis of your need and response to treatment. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Some common side effects of this medicine include nausea, headache, lightheadedness, lethargy, and abdominal pain. It is advised to drink at least 1 liter of fluid daily when you are on treatment with this medicine. You should seek immediate medical attention if you experience severe allergic reactions like rash, itching, breathing difficulty, chest tightness, and swelling of the mouth, face, lips, or tongue while taking this medicine. Regular blood tests are required to check your blood cells along with the kidney, liver, and blood uric acid levels.

Before taking it, tell your doctor if you have an autoimmune disorder, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Uromitexan Infusion

Benefits of Uromitexan Infusion

In Treatment of Ifosfamide-induced hemorrhagic cystitis

Ifosfamide-induced hemorrhagic cystitis is an inflammatory condition due to the use of a medicine called Ifosfamide that causes bleeding in the bladder. Uromitexan Infusion helps to suppress the body’s immune system, thereby reducing the progression of the disease. It reduces the inflammation of the damaged area, prevents further damage and stabilises your condition

Side effects of Uromitexan Infusion

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Uromitexan

  • Nausea
  • Headache
  • Lightheadedness
  • Lethargy
  • Abdominal pain
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Diarrhea
  • Rash
  • Fever
  • Flu-like symptoms

How to use Uromitexan Infusion

Your doctor or nurse will give you this medicine. Kindly do not self-administer.

How Uromitexan Infusion works

Uromitexan Infusion helps to reduce the risk of inflammation and bleeding in the bladder, who receive ifosfamide (a medicine used to treat cancer).

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Uromitexan Infusion. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
Uromitexan Infusion is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
UNSAFE
Uromitexan Infusion is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Uromitexan Infusion may cause side effects which could affect your ability to drive.
As patients undergoing treatment with Uromitexan Infusion may experience undesirable effects such as lightheadedness, lethargy, dizziness, and blurred vision which could affect the ability to drive.
Kidney
CAUTION
Uromitexan Infusion should be used with caution in patients with kidney disease. Dose adjustment of Uromitexan Infusion may be needed. Please consult your doctor.
Liver
CAUTION
Uromitexan Infusion should be used with caution in patients with liver disease. Dose adjustment of Uromitexan Infusion may be needed. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Quick Tips

  • Uromitexan Infusion is given as in injection or infusion under the supervision of a doctor only.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • It is advisable to drink plenty of water to stay hydrated while taking this medicine.
  • Your doctor may get a regular urine and blood tests done to monitor your blood cell count (CBC).

Fact Box

Chemical Class
Sulfhydryl compound, {organosulfonic acid}
Habit Forming
No
Therapeutic Class
BLOOD RELATED

Patient Concerns

arrow
Cystitis, left renal calculi. .
Dr. Aanchal Maheshwari
Ayurveda
Take tablet neeri , tablet cystone, tablet chandraprabha vati all 3, 2 tablet twice daily water. Drink more of water
Cystitis, frequent urination , pain at urinary bladder site
Dr. Praveen Pushkar
Urology
Get urine routine examination n culture done
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Do you have any questions related to Uromitexan Infusion ?

FAQs

Q. Why it is given with ifosamide or cyclophosphamise (Cytoxan)?

It is given along with the chemotherapy drug ifosfamide or cyclophosphamide to reduce the side effects of these drugs

Q. Is mesna compatible with potassium chloride and doxorubicin?

Yes, Mesna is compatible with potassium chloride and doxorubicin

Q. Is Uromitexan Infusion a chemotherapy drug?

Uromitexan Infusion is not a chemotherapy drug

Q. Is Uromitexan Infusion cytotoxic?

No. Uromitexan Infusion is not cytotoxic drug. It is cytoprotective drug

Q. Is Uromitexan Infusion a vesicant?

No, Uromitexan Infusion is not a vesicant.

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Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 870-71.
  2. Mesna. Thetford, Norfolk: Baxter Healthcare Ltd.; 2003 [revised Oct. 2014]. [Accessed 28 Jan. 2019] (Online) Available from:External Link
  3. Mesna. Los Angeles, California: American pharmaceutical partners; 2001. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Medscape. Mesna. [Accessed 26 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Zydus Tower, Satellite Cross Roads,Ahmedabad – 380015 Gujarat, India.
Country of Origin: India

Expires on or after: June, 2021

A licensed vendor partner from your nearest location will deliver Uromitexan Infusion. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
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