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Tyro 4% Cream

Hydroquinone (4% w/w)

Genuine

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Prescription

required

Tyro 4% Cream is used in the treatment of melasma. It is a skin-lightening medicine that lightens the darkened skin patches and spots(hyperpigmentation). It reduces the amount of skin-darkening pigment called melanin in the skin. It helps in reversible depigmentation of the skin.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 17 Jan 2026 | 08:33 PM (IST)

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General Information

Contains

Hydroquinone (4% w/w)

Marketer

ICI Pharmaceuticals

Storage

Store below 30°C

The content is shown in English

Product introduction

Tyro 4% Cream is for external use only. You should use it in the dose and duration as advised by your doctor. You must wash your hands thoroughly before and after applying this medicine. This medicine should be used regularly to get the most benefit from it. Do not use more than you need, as some side effects may be increased.

Tyro 4% Cream has a few potential side effects, but not everyone will get them. These may include dry skin, itching, skin burn, skin peeling, and skin redness. Serious allergic reactions to this drug are rare, but let your doctor know if you’re bothered by side effects or if they do not go away. Make sure you read the instructions that come with your medicine. Avoid contact with the eyes. In case of accidental contact, you should rinse your eyes thoroughly with water.

You can start applying Tyro 4% Cream to a small portion of unbroken skin or near the pigmented area for a period of several days for checking an allergic reaction. You should discontinue it if itching, excessive inflammation, or swelling occurs. Pregnant women should consult their doctor before taking this medicine. If no improvement is seen after two months of treatment, the use of this product should be discontinued.

Uses of Tyro Cream

Treatment of Melasma

Benefits of Tyro Cream

Treatment of Melasma
Melasma is a common skin problem that causes dark, discolored patches on your skin. It is more commonly seen in females than in males. Tyro 4% Cream helps to lighten these dark patches of the skin, usually caused by pregnancy, birth control pills, hormone medicine, or injury to the skin. It effectively blocks that process in the skin that leads to discoloration. Tyro 4% Cream also reduces any redness, rash, pain, or itchiness that may be caused by this condition.

Side effects of Tyro Cream

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tyro

Stinging sensation
Erythema (skin redness)
Dryness and fissuring of paranasal and infraorbital areas

How to use Tyro Cream

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the cream. Wash your hands after applying, unless hands are the affected area.

How Tyro Cream works

Tyro 4% Cream blocks steps in melanin production by inhibiting the enzyme tyrosinase and other melanocyte processes. This reduces the amount of pigment (melanin) in the treated skin, leading to reversible lightening of dark patches.

All substitutes for Tyro 4% Cream

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Tyro 4% Cream should always be used along with sun-avoidance measures, like using sunscreens (UV-A and UV-B protective) and wearing protective clothing.
Avoid getting it in your eyes or mouth. If this happens, rinse with water immediately.
Apply it as per the dose and duration advised by your doctor with regular follow-up.
Apply a very small amount of cream to check for an allergic reaction. Continue with the treatment if no allergic reaction occurs in 24 hours.
Do not apply to broken or infected areas of skin. Discontinue use if you experience irritation or an allergy and consult your doctor.

Safety advice

Alcohol

No interaction found/established

Pregnancy

CONSULT YOUR DOCTOR

The safety of Tyro 4% Cream during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Tyro 4% Cream during breastfeeding is not available. Please consult your doctor.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

Frequently asked questions

Is Tyro 4% Cream safe to use on the face?

Tyro 4% Cream should be used exactly as directed by your doctor. You should apply it away from the eyes, nose, corners of the mouth, or open wounds because these areas are more prone to irritation. If local irritation persists or becomes severe, discontinue Tyro 4% Cream and consult your doctor. Excessive use of the medication may cause redness, peeling, or discomfort.

Does Tyro 4% Cream permanently lighten skin?

No, it does not lighten the skin permanently. If melasma occurs on discontinuing Tyro 4% Cream, talk to your doctor regarding the maintenance treatment of melasma.

What should I avoid when using Tyro 4% Cream?

You should avoid exposure to sunlight, use sunscreen, and wear protective clothing after treatment with Tyro 4% Cream cream. Even a small amount of sunlight can worsen melasma. Females should avoid the use of birth control methods that contain hormones, such as oral birth control pills, as these methods can worsen their melasma. Talk to your doctor about other birth control options. Be careful, as hot and cold weather may irritate the skin treated with Tyro 4% Cream.

How should Tyro 4% Cream be applied?

Tyro 4% Cream should be applied once a day, before bedtime. The area to be treated should be thoroughly washed with water. Apply a thin layer of Tyro 4% Cream to the affected skin areas. Include about half an inch of normal skin surrounding the affected area. Gently rub Tyro 4% Cream evenly into your skin. Do not apply it near the corners of your mouth, nose, eyes, or open wounds.

Can I apply moisturizer over Tyro 4% Cream?

Tyro 4% Cream is applied generally at bedtime. You may use moisturizers and cosmetics during the day when you are not using Tyro 4% Cream.

Is Tyro 4% Cream bad for the skin?

Tyro 4% Cream may cause blue-black darkening of the skin. If this occurs, you should immediately stop Tyro 4% Cream and consult your doctor. In some cases, it may also cause mild to moderate irritation, such as skin reddening, peeling, mild burning sensation, dryness, and itching at the site of application. But this is usually tolerable and may disappear with time.

Fact Box

Chemical Class

Hydroquinones

Habit Forming

Therapeutic Class

DERMA

Action Class

Anti Pigmentation & Skin Lightening Agents

References

Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1055.
Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1830.
Ghosh S. Acne Variants and Scenarios. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 155.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 668-69.
Hydroquinone [Product Monograph]. Montréal, Canada: ERFA Canada Inc.; 2019.

User feedback

What are you using Tyro Cream for?

Melasma

54%

Others

46%

How much was the improvement?

Poor

40%

Excellent

33%

Average

27%

What were the side-effects while using Tyro 4% Cream?

No Side Effect

100%

How do you take Tyro Cream?

With or without food

50%

With food

50%

Please rate Tyro 4% Cream on price

Not Expensive

50%

Expensive

50%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: ICI Pharmaceuticals
Address: Hubli, Karnataka, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Tyro 4% Cream. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Tyro 4% Cream

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Tyro Cream

Benefits of Tyro Cream

Side effects of Tyro Cream

How to use Tyro Cream

How Tyro Cream works

All substitutes for Tyro 4% Cream

Eukroma Cream

Melalite Forte Cream

Melapik -HQ Cream

Melanorm Cream

BRite Cream

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Is Tyro 4% Cream safe to use on the face?

Does Tyro 4% Cream permanently lighten skin?

What should I avoid when using Tyro 4% Cream?

How should Tyro 4% Cream be applied?

Can I apply moisturizer over Tyro 4% Cream?

Is Tyro 4% Cream bad for the skin?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

What are you using Tyro Cream for?

How much was the improvement?

What were the side-effects while using Tyro 4% Cream?

How do you take Tyro Cream?

Please rate Tyro 4% Cream on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

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