Tucanat Tablet

Tucatinib (150mg)

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Product Summary :

Tucanat Tablet is an anticancer medicine containing tucatinib that is used to treat HER2-positive breast cancer. It is used for adult patients where surgery can not be performed or in conditions where cancer has already spread to different body parts. It works by blocking the HER2 protein that is responsible for cancer cell growth. It is usually taken twice a day (every 12 hours), with or without food. Take it exactly as prescribed by the doctor. Common side effects include diarrhea, nausea, vomiting, and rash, among others. Do not take it if you are pregnant or breastfeeding. Inform your doctor if you have existing kidney or liver problems before taking this medicine.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 08 Oct 2026 | 01:03 AM (IST)

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General Information

Contains

Tucatinib (150mg)

Marketer

Natco Pharma Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Tucanat Tablet is an anticancer medicine that is used with other anticancer medicines to treat adults with HER2-positive, unresectable (cannot be removed surgically), or metastatic breast cancer (that has spread to other body parts). It works by blocking HER2 signals that help cancer cells grow and survive.

HER2-positive cells are the cells that have HER2 protein, which may cause cancer to grow quickly if they are present in high quantities. Tucanat Tablet acts on these cells by blocking their activities, which may slow or stop the cancer from growing and spreading.

Take Tucanat Tablet exactly as prescribed by your doctor. It is usually taken twice a day at about the same time each day (at a gap of 12 hours) with or without food. Take it regularly and do not change the dose or stop treatment unless advised by your doctor.

Common side effects of Tucanat Tablet may include diarrhea, nausea, vomiting, and rash. Drink enough fluids to prevent dehydration in case of diarrhea. Inform your doctor if diarrhea is severe or it continues.

Tucanat Tablet may require regular liver function tests during treatment. Inform your doctor if you have any liver disease, all medicines, supplements, and herbal products you take. Tucanat Tablet can harm an unborn baby; it should not be used during pregnancy unless specifically advised by your doctor. Men and women should use effective contraception during treatment and for at least 1 week after the last dose. Breastfeeding should be discontinued during treatment and for 1 week after the last dose.

Uses of Tucanat Tablet

Treatment of Breast cancer : Tucanat Tablet is used to slow the growth and spread of HER2-positive breast cancer. It is specifically used in cases where cancer has spread to other body parts such as the brain or it cannot be surgically removed.

Benefits of Tucanat Tablet

Treatment of Breast cancer
Breast cancer may develop when abnormal breast cells grow uncontrollably and may spread to other parts of the body. Tucanat Tablet helps slow cancer cell growth and makes it harder for them to survive. This may help control the disease and also slow down its progression, which can help improve overall outcomes of the treatment.

Side effects of Tucanat Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Tucanat

Diarrhea
Nausea
Vomiting
Increased liver enzymes
Rash
Decreased appetite

How to use Tucanat Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tucanat Tablet may be taken with or without food.

How Tucanat Tablet works

Certain breast cancers have higher-than-normal levels of a protein called HER2, which can send signals that help cancer cells grow and multiply. Tucanat Tablet blocks the activity of HER2, helping to reduce these growth signals and slow the growth and spread of cancer cells.

Dosage

Tucanat Tablet is usually taken twice daily, keeping a 12-hour gap between doses, or at the same times each day, as prescribed by your doctor depending on your condition and how well you tolerate the medicine.

Quick tips

Take Tucanat Tablet under the supervision of a doctor and do not stop taking it unless your doctor advises you to do so.
Tucanat Tablet may cause diarrhea in some people. Drink plenty of fluids if you are taking this medicine dehydration. If the diarrhea persists, consult your doctor.
Limited studies suggest that Tucanat Tablet may impair fertility in males and females. If you are planning to have a baby, consult your doctor before taking this medicine.
Use effective contraception methods during the treatment and at least 1 week after your last dose.

Safety advice

Alcohol

SAFE

Consuming alcohol with Tucanat Tablet does not usually cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Tucanat Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Tucanat Tablet during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Tucanat Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Tucanat Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Tucanat Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Frequently asked questions

What is Tucanat Tablet used for?

Tucanat Tablet is used in the treatment of breast cancer in combination with other anticancer medicines. It is used to treat HER2-positive breast cancer patients. It is prescribed to treat adults who have already received one or more prior anti-HER2-based treatment regimens.

Can Tucanat Tablet alone treat breast cancer?

No. It is commonly used along with a few other anticancer medicines. Always take it after consulting an oncologist.

Is Tucanat Tablet a medicine for chemotherapy?

Tucanat Tablet is an anticancer medicine that is used for targeted therapy. It does not generally affect rapidly dividing cells the way other anticancer drugs work. It is usually prescribed by an oncologist in combination with other anticancer medicines in adults who have received one or more prior anti-HER2-based treatment regimens.

Can Tucanat Tablet affect the liver?

Yes. Tucanat Tablet can increase certain liver enzymes and bilirubin. Always inform your doctor if you have pre-existing liver issues. Your doctor may do regular check-ups to monitor liver function during treatment. If you experience symptoms like persistent yellowing of the skin or eyes, dark urine, unusual tiredness, or abdominal discomfort, consult your doctor about them.

Can I take Tucanat Tablet if I am pregnant?

No. Tucanat Tablet may harm the developing baby and should be avoided during pregnancy. Inform your doctor if you are planning to become pregnant or are pregnant while taking the treatment. Your doctor will decide the risk and benefit of using it in case you are pregnant.

Can I breastfeed while taking Tucanat Tablet?

There is limited information available on whether Tucanat Tablet is safe during breastfeeding. Consult your doctor before consuming it during breastfeeding. However, as a precaution, it is also advised to stop breastfeeding for a week while taking Tucanat Tablet and resume after 1 week from the last dose.

Fact Box

Chemical Class

Quinazolinamines

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Tyrosine Kinase Inhibitors (TKIs)

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Natco Pharma Ltd
Address: Natco House, Road No.2, Banjara Hills, Hyderabad-500 034, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Tucanat Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

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Tucanat Tablet

Product Summary :

Payment, Returns & Expiry

Online payment only

7 day free return

Product expires after Jun, 2027

Price Info

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Tucanat Tablet

Benefits of Tucanat Tablet

Side effects of Tucanat Tablet

How to use Tucanat Tablet

How Tucanat Tablet works

Dosage

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

What is Tucanat Tablet used for?

Can Tucanat Tablet alone treat breast cancer?

Is Tucanat Tablet a medicine for chemotherapy?

Can Tucanat Tablet affect the liver?

Can I take Tucanat Tablet if I am pregnant?

Can I breastfeed while taking Tucanat Tablet?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests