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Trizone Forte Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 22 Dec 2025 | 02:56 PM (IST)
Trizone Forte Tablet is a combination medicine used in the treatment of pain due to muscle spasm. It improves the movement of muscles and provides relief from pain and discomfort associated with muscle spasms.
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General Information

Contains

Nimesulide (100mg)+ Paracetamol (500mg)+ Tizanidine (2mg)

Marketer

Zee Laboratories

Storage

Store below 30°C
The content is shown in English
Trizone Forte Tablet image
Trizone Forte Tablet image

Product introduction

Trizone Forte Tablet may be prescribed alone or in combination with another medicine. It is best taken with food. This will prevent you from getting an upset stomach. You should take it regularly as advised by your doctor. Do not take more or use it for longer duration than recommended by your doctor.

Using this medicine may cause few common side effects such as nausea, vomiting, diarrhea, stomach upset, and sleepiness. If you experienced any such side effects that do not resolve with time or get worse, you should let your doctor know. Your doctor may help with ways to reduce or prevent them.

The medicine may not be suitable for everybody. Before taking it, let your doctor know if you have any medical conditions or disorders. Let your doctor also know all the other medicines you are taking to make sure it is safe. Pregnant and breastfeeding mothers should consult their doctors first before using the medicine.


Note: As per the Ministry of Health and Family Welfare, Trizone Forte Tablet is banned for children under 12 years of age.

Uses of Trizone Forte Tablet

  • Pain due to muscle spasm

Benefits of Trizone Forte Tablet

Pain due to muscle spasm
Trizone Forte Tablet is a combination medicine that contains painkiller as well as a muscle relaxant. It is used to relieve pain, inflammation, and swelling in conditions that affect muscles. Also, it effectively relieves muscle stiffness or spasm, thereby improving muscle movement. Trizone Forte Tablet also reduces fever associated with muscular pain. It works by blocking certain chemicals that cause pain and fever. By reducing pain, it improves the quality of your life.

Side effects of Trizone Forte Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trizone Forte
  • Nausea
  • Vomiting
  • Diarrhea
  • Sleepiness
  • Weakness
  • Increased liver enzymes
  • Dryness in mouth

How to use Trizone Forte Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trizone Forte Tablet should be taken with or after food.

How Trizone Forte Tablet works

Trizone Forte Tablet is a combination of three medicines: Nimesulide, Paracetamol and Tizanidine which relieve pain and relax the muscles.Nimesulide is a non-steroidal antiinflammatory drug (NSAID) and Paracetamol is an antipyretic (fever reducer). They work by blocking the release of certain chemical messengers in the brain that cause pain and fever. Tizanidine is a muscle relaxant. It works on brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

All substitutes for Trizone Forte Tablet

For information purposes only. Consult a doctor before taking any medicine.

Neegard Tablet

by Badrivas Biotech Pvt Ltd
₹5.91/tablet
36% costlier
<h3 class=bodySemiBold>Neegard Tablet</h3>

Ingesic MR Tablet

by Pacific Biotech
₹5.05/tablet
17% costlier
<h3 class=bodySemiBold>Ingesic MR Tablet</h3>

Quick tips

  • You have been prescribed Trizone Forte Tablet to get relief from pain and stiffness in the muscles.
  • Take it with food or milk to prevent an upset stomach.
  • You may see results within 1.5 to 2 hours after taking Trizone Forte Tablet. Take it exactly as advised by your doctor.
  • Avoid consuming alcohol while taking Trizone Forte Tablet as it can increase your risk of stomach problems.
  • Inform your doctor if you have a history of seizures.
  • Inform your doctor if you are taking any other medications with Paracetamol in them.
  • Along with taking Trizone Forte Tablet, your doctor might advise you to undergo physiotherapy to get relief from muscle pain.

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Trizone Forte Tablet
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Trizone Forte Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Trizone Forte Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

UNSAFE
Trizone Forte Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Trizone Forte Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

UNSAFE
Trizone Forte Tablet is unsafe to use in patients with liver disease and should be avoided.

Frequently asked questions

Trizone Forte Tablet is prescribed to relieve pain, inflammation, and muscle spasms. It is commonly used for muscle pain due to injuries or sprains, arthritis flare-ups, back pain, and spasms related to muscle or joint conditions.
Do not take Trizone Forte Tablet if you are allergic to any of its ingredients, have active liver disease, severe kidney disease, stomach ulcers, bleeding disorders, or a history of severe heart disease or allergic reactions to painkillers.
Before using Trizone Forte Tablet, tell your doctor if you have liver, kidney, or heart problems, a history of alcohol abuse, or if you are elderly. Avoid taking other painkillers or muscle relaxants at the same time unless prescribed. Use with caution if you have low blood pressure, as this medicine may further lower it.
Serious side effects of Trizone Forte Tablet include persistent nausea and vomiting, yellowing of the skin or eyes (possible liver problems), severe abdominal pain, black or bloody stools, difficulty breathing, chest pain, dizziness, or unusual muscle weakness. Seek immediate medical attention if you experience any of these symptoms.
Trizone Forte Tablet may affect liver function, especially with prolonged or excessive use. Avoid alcohol and do not exceed the prescribed dose to reduce this risk. Inform your doctor about any history of liver issues.

Fact Box

Habit Forming

No

Therapeutic Class

PAIN ANALGESICS

References

  1. Patil S, Nadaf N, Gupta S, et al. A Comparative Analysis of the Efficacy and Safety of Nimesulide/Paracetamol Fixed-Dose Combination With Other NSAIDs in Acute Pain Management: A Randomized, Prospective, Multicenter, Active-Controlled Study (the SAFE-2 Study). Cureus. 2024;16(4):e58859. [Accessed 22 Dec. 2025]. Available from:
  2. Malanga G, Reiter RD, Garay E. Update on tizanidine for muscle spasticity and emerging indications. Expert Opin Pharmacother. 2008 Aug;9(12):2209-15. [Accessed 22 Dec. 2025]. Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Zee Laboratories
Address: Uchani, G.T. Road, Karnal-132001 Haryana (INDIA)

Vendor Details

Country of origin: India

Lab tests offered by us

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