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Trinicalm Plus Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS
Last updated on 09 Feb 2026 | 03:40 PM (IST)
Trinicalm Plus Tablet is a combination medicine used in the treatment of schizophrenia (a mental disorder in which a person develops unreal thoughts and behavior). It alters the thoughts and elevates the mood, improving the person’s ability to think, feel and behave.
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Trinicalm Plus Tablet image
Trinicalm Plus Tablet image
Trinicalm Plus Tablet image
Trinicalm Plus Tablet image
Trinicalm Plus Tablet image
Trinicalm Plus Tablet image

Product introduction

Trinicalm Plus Tablet also helps by improving muscle control and reducing the stiffness of the muscle. It may be taken with or without food, preferably at the same time each day. Take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor and if you have missed a dose, take it as soon as you remember it. Do not skip any doses and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may worsen your symptoms.

Some common side effects of this medicine include nausea, constipation, dryness in mouth, sedation, abnormal heart rhythm, urinary retention, blurred vision, and nervousness. Initially, this medicine may cause a sudden drop in blood pressure when you change positions, rise slowly if you have been sitting or lying down. It may also cause dizziness and sleepiness, do not drive or do anything that requires mental focus until you know how this medicine affects you.

Before taking it, inform your doctor if you are suffering from thyroid or kidney problems, epilepsy, Parkinson’s disease, glaucoma, or any heart problems. You should not take this medicine if you are under the influence of alcohol or any sleep-inducing, cough, and/ or allergy medication. This medicine can also lead to weight gain, eat a healthy balanced diet, avoid snacking with high-calorie food, and exercise regularly.

Uses of Trinicalm Plus Tablet

Benefits of Trinicalm Plus Tablet

Schizophrenia
Schizophrenia is a mental disorder in which a person’s thinking ability, feelings and behavior become abnormal. Trinicalm Plus Tablet helps restore the chemical imbalances in the brain that are responsible for such changes. It improves thoughts, behavior and enhances the quality of life.

Side effects of Trinicalm Plus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Trinicalm Plus
  • Nausea
  • Constipation
  • Dryness in mouth
  • Sedation
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • Increased prolactin level in blood
  • Dizziness
  • Blurred vision
  • Nervousness

How to use Trinicalm Plus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trinicalm Plus Tablet may be taken with or without food.

How Trinicalm Plus Tablet works

Trinicalm Plus Tablet is a combination of two medicines: Trifluoperazine and Trihexyphenidyl. Trifluoperazine is a typical antipsychotic. It works by blocking the action of a chemical messenger (dopamine) in the brain that affects thoughts and mood. However, it may cause side effects such as involuntary movements (shaking of hands, muscle spasms). Trihexyphenidyl is added to treat and prevent these side effects.

Quick tips

  • Trinicalm Plus Tablet is a combination medicine that helps treat schizophrenia.
  • Be cautious while driving or doing anything that requires concentration as Trinicalm Plus Tablet can cause dizziness and sleepiness.
  • It can cause dry mouth. Maintain good oral hygiene,drink water, chew sugarless gum, or suck on hard candy for the dry mouth.
  • It can make you more sensitive to changes in temperature. Drink plenty of liquids and dress appropriately.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • Inform your doctor if you have glaucoma or trouble passing urine.
  • Do not stop taking Trinicalm Plus Tablet without talking to your doctor first as it may cause worsening of symptoms.

Safety advice

Alcohol

Alcohol

CAUTION
Alcohol should be used with caution while taking Trinicalm Plus Tablet.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Trinicalm Plus Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Trinicalm Plus Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving

Driving

UNSAFE
Trinicalm Plus Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Trinicalm Plus Tablet can cause blurring of vision, dizziness, mild nausea, and mental confusion in some cases. This may affect your ability to drive.
Kidney

Kidney

CAUTION
Trinicalm Plus Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Patients with kidney disease should be closely monitored by a doctor while taking this medicine.
Liver

Liver

CAUTION
Trinicalm Plus Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Everybody responds to the treatment differently. In general, it can take several weeks to feel the full benefits of Trinicalm Plus Tablet, although some people may start to feel better sooner. It is important to give this drug the time to work.
No, you should continue taking Trinicalm Plus Tablet even if you feel well. If you stop Trinicalm Plus Tablet suddenly, serious withdrawal problems may occur. Your doctor will probably decrease your dose gradually before asking you to stop Trinicalm Plus Tablet.
Yes, Trinicalm Plus Tablet can make you feel sleepy. Avoid driving, operating machinery, working at heights or participating in potentially dangerous activities till you know how this medicine affects you.
Yes, the use of Trinicalm Plus Tablet can cause dry mouth. If you experience dry mouth, drink plenty of water. Take regular sips during the day and keep some water by your bed at night. You may use lip balm if your lips are also dry. Try to avoid foods that are acidic (like lemons), spicy and salty.
Keep this medicine in the packet or the container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

No

Therapeutic Class

NEURO CNS
Related ayurvedic ingredients
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Once A Day
60%
Twice A Day
40%
Schizophrenia
79%
Others
16%
Drug induced abnormal movements
4%
Parkinson's disease
2%
Average
54%
Excellent
25%
Poor
22%
No Side Effect
38%
Dryness in mouth
12%
Sleepiness
6%
Weight gain
6%
Blurred vision
6%
With food
71%
With or without food
21%
Empty stomach
7%
Expensive
45%
Not Expensive
30%
Average
24%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Torrent Pharmaceuticals Ltd
Address: Off. Ashram Road, Ahmedabad - 380 009., Gujarat, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Trinicalm Plus Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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